Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0040425 (
tonsillitis
)
1,594
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The content of medium-weight molecules (MWM) in the plasma was evaluated by the screening method in 280 patients with prevalent infectious diseases (viral hepatitides A, B, and C, influenza, acute
dysentery
, alimentary toxicoinfections, and
tonsillitis
). Control group consisted of 70 donors. The maximum levels of MWM were observed at the peak of disease. In viral infections the increase in the level of MWM was longer. The values of MWM depended on the disease severity and presence of the intoxication syndrome. Plasma concentration of MWM correlated with the presence of the leading clinical syndromes in infectious diseases. Measurement of MWM level in the plasma of infectious patients can be used as a criterion of recovery and a prognostic and additional diagnostic test.
...
PMID:[The significance of detecting medium-weight molecules in the plasma of patients with viral and bacterial infectious]. 1087 91
The fruits of Paulownia catalpifolia Gong Tong are used as a Chinese folk herbal medicine for the treatment of enteritis,
tonsillitis
, bronchitis, and
dysentery
, etc. Our previous study has identified new C-geranylated flavanones with obvious anti-proliferative effects in lung cancer A549 cells. In the present study, a new C-geranylated flavone, paucatalinone C (1) and five known C-geranylated flavanones (2-6) were isolated. In addition, a total of 34 C-geranylated flavonoids were detected by HPLC-DAD-ESI-MS/MS coupling techniques from the CH
2
Cl
2
extract of P. catalpifolia. Futhermore, anti-aging effects of isolated compounds were evaluated in vitro with premature senescent 2BS cells induced by H
2
O
2
. Phytochemical results indicated that P. catalpifolia was a natural resource of abundant C-geranylated flavonoids. Diplacone (3) and paucatalinone A (5) were the potent anti-aging agents in the premature senescent 2BS cells induced by H
2
O
2
and the C-geranyl substituent may be an important factor because of its lipophilic character.
...
PMID:Identification of C-geranylated flavonoids from Paulownia catalpifolia Gong Tong fruits by HPLC-DAD-ESI-MS/MS and their anti-aging effects on 2BS cells induced by H
2
O
2
. 2855 74
