Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0039730 (thalassemia)
 10,305 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
beta-globin 0.022
HBB 0.012
hemoglobin 0.009
HBA2 0.007
alpha globin 0.005
gamma-globin 0.005
beta globin 0.004
HBA1 0.003
delta-globin 0.003
ferritin 0.003
BCL11A 0.003
I-1 0.003
HBG2 0.002
ATRX 0.001
HBS1L 0.001
erythroid 0.001
gamma globin 0.001
ATRX protein 0.001
beta globin chain 0.001
melanin-concentrating hormone 0.001
mutant beta-globin 0.001
delta globin 0.001
HBG1 0.001
HBD 0.001
methemoglobin 0.001
gamma-globin chain 0.000
delta-globin chain 0.000
MED 0.000
KLF1 0.000
hereditary hemochromatosis 0.000
ARMS 0.000
Alpha-hemoglobin-stabilizing protein 0.000
alpha 1 globin 0.000
OR51V1 0.000
DAXX 0.000
alpha-chain 0.000
XNP 0.000
hemochromatosis 0.000
truncated beta-globin 0.000
Beta-globin 0.000
OR52A1 0.000
HBD/HBB 0.000
OR51A1P 0.000
OR52A5 0.000
OR52Z1 0.000
ARHGDIG 0.000
theta-1 0.000
Hepcidin 0.000
transferrin 0.000
X-linked) 0.000
mitochondrial intermediate peptidase 0.000
zeta 2 0.000
erythropoietin 0.000
G-gamma 0.000
X-linked protein 0.000
beta globin variant 0.000
LARP2 0.000
G-gamma globin 0.000
OR52A4 0.000
gamma chain 0.000
AAG 0.000
alpha-2 globin 0.000
DAXX protein 0.000
alpha 2 globin 0.000
TMPRSS6 0.000
hemoglobin alpha 2 0.000
EKLF 0.000
hemoglobin beta 0.000
pseudoxanthoma elasticum 0.000
H3 histone, family 3A 0.000
Zeta-globin 0.000
HOR5 0.000
Gamma globin 0.000
Beta globin 0.000
glucose-6-phosphate dehydrogenase 0.000
endonuclease 0.000
HS2 0.000
transferrin receptor 0.000
HFE 0.000
heme-regulated inhibitor 0.000
more...
Disease
thalassemia 1.000
thalassemia major 0.037
hemoglobinopathies 0.032
beta thalassemia 0.021
sickle cell disease 0.018
iron overload 0.016
thalassemia trait 0.015
HBB 0.012
HBB 0.012
HBB 0.012
alpha thalassemia 0.008
hereditary persistence of fetal hemoglobin 0.006
thalassemia minor 0.006
HPFH 0.004
anemia 0.003
Thalassemia intermedia 0.003
microcytic anemia 0.003
ATRX 0.001
hypochromic anemia 0.001
iron deficiency 0.001
hemolytic anemia 0.001
G6PD deficiency 0.001
hereditary spherocytosis 0.001
hereditary anemia 0.001
blood disorder 0.001
ATMDS 0.001
hemosiderosis 0.001
iron deficiency anemia 0.001
acute chest syndrome 0.001
HBD 0.001
siderosis 0.001
hemochromatosis 0.000
Beta thalassaemia trait 0.000
Hb SC disease 0.000
hereditary hemochromatosis 0.000
sickle thalassemia 0.000
congenital hemolytic anemia 0.000
Hemoglobin E trait 0.000
Hb-C disease 0.000
hypersplenism 0.000
pyruvate kinase deficiency 0.000
XLTT 0.000
X-linked alpha-thalassemia/mental retardation syndrome 0.000
syndrome X 0.000
dyserythropoietic anemia 0.000
malaria 0.000
hereditary elliptocytosis 0.000
congenital anemia 0.000
Cardiac siderosis 0.000
Alpha thalassemia major 0.000
mental retardation 0.000
mental retardation 0.000
CAA 0.000
myelodysplastic anemia 0.000
genetic disorder 0.000
anemia of chronic disease 0.000
Acquired hemoglobinopathy 0.000
Alpha thalassemia intermedia 0.000
F thalassaemia 0.000
Other hemoglobinopathies 0.000
Homozygous alpha thalassaemia 0.000
HPFH deletion type 0.000
Pigment cirrhosis 0.000
Hb-SD 0.000
Other mental retardation 0.000
Tonsillar actinomycosis 0.000
G6PD deficiency anemia 0.000
graft-versus-host disease 0.000
erythrocytosis 0.000
Sickle cell thalassemia 0.000
pseudoxanthoma elasticum 0.000
aplastic anemia 0.000
CAA 0.000
Splenic sequestration 0.000
spinal cord compression 0.000
hypogonadism 0.000
leg ulcers 0.000
myelodysplastic syndrome 0.000
Chronic anemia 0.000
Hydrops fetalis 0.000
more...
Symptom
splenomegaly 0.001
hepatosplenomegaly 0.000
pallor 0.000
hepatomegaly 0.000
Reticulocytosis 0.000
paraparesis 0.000
Cutaneous anergy 0.000
left upper quadrant pain 0.000
cardiovascular impairment 0.000
Organ failure 0.000
bone pain 0.000
lumbar back pain 0.000
arthralgia 0.000
pain 0.000
non-productive cough 0.000
No adverse effect 0.000
back pain 0.000
acute pain 0.000
generalized pain 0.000
Opposition 0.000
labored breathing 0.000
asthenia 0.000
stomach pain 0.000
disturbed balance 0.000
thinning 0.000
muscle rigidity 0.000
dyspnea 0.000
nausea 0.000
cyanosis 0.000
headache 0.000
shortness of breath 0.000
abdominal pain 0.000
Scratch 0.000
chills 0.000
diarrhea 0.000
hypoproteinemia 0.000
leg pain 0.000
seizures 0.000
fatigue 0.000
Decreased activity 0.000
ankle pain 0.000
epigastric pain 0.000
breath holding 0.000
tingling 0.000
numbness 0.000
Gastrointestinal symptoms 0.000
weakness 0.000
dizziness 0.000
Fluctuation 0.000
lethargy 0.000
atypical chest pain 0.000
vomiting 0.000
myalgia 0.000
abdominal discomfort 0.000
chest tightness 0.000
acute abdomen 0.000
stigma 0.000
exertional dyspnea 0.000
chest pain 0.000
exhaustion 0.000
anorexia 0.000
discomfort 0.000
fever of unknown origin 0.000
discomfort 0.000
dry skin 0.000
emaciation 0.000
eds 0.000
masculinization 0.000
decreased appetite 0.000
wheezing 0.000
anesthesia 0.000
respiratory distress 0.000
paresthesia 0.000
Ill 0.000
snoring 0.000
regurgitation 0.000
tonic-clonic seizure 0.000
bitter taste 0.000
physical appearance 0.000
low back pain 0.000
more...
Drug
Deferasirox 0.002
Desferal 0.000
VCR 0.000
Methylhydrazine 0.000
AGG 0.000
Deferoxamine mesylate 0.000
Desferal 0.000
Hakka 0.000
Sodium phenylbutyrate 0.000
TRM 0.000
Cellulose acetate 0.000
Atarax 0.000
Glucose-6-Phosphate 0.000
Phosphatidylserine 0.000
Epoetin alfa 0.000
TAT 0.000
Benserazide 0.000
vitamin E 0.000
Lariam 0.000
Asn 0.000
Heme 0.000
CET 0.000
Sonata 0.000
Zoledronic acid 0.000
Ferrous sulfate 0.000
Zoledronic acid 0.000
Sodium thiosulfate 0.000
Fludarabine 0.000
ascorbate 0.000
Ipriflavone 0.000
Denosumab 0.000
Colombo 0.000
DNase I 0.000
DFP 0.000
Tenofovir disoproxil fumarate 0.000
G-CSF 0.000
G418 0.000
Daclizumab 0.000
Growth hormone 0.000
Epoetin alfa 0.000
Antithrombin III 0.000
Growth hormone 0.000
lysine 0.000
CTM 0.000
Fansidar 0.000
Fansidar 0.000
TES 0.000
Compound 9 0.000
Clodronate 0.000
TAC 0.000
Luteinizing 0.000
Pyridoxal 0.000
Zmax 0.000
Cobalamin 0.000
Epoetin 0.000
CTM 0.000
Campath 0.000
Campath 0.000
Dakar 0.000
NAG 0.000
FAD 0.000
Piracetam 0.000
MDS 0.000
Vorinostat 0.000
Vitamin E 0.000
Kenyan 0.000
SBT 0.000
CTT 0.000
Fluorescein 0.000
Activin 0.000
Fluorescein 0.000
Finasteride 0.000
PFA 0.000
CTC 0.000
Emodin 0.000
Orphan 0.000
ACT 0.000
Vitamin B12 0.000
CTC 0.000
Emodin 0.000
more...
Enzyme
endonuclease 0.000
glucose-6-phosphate dehydrogenase 0.000
ERK 0.000
BMT 0.000
alanine aminotransferase 0.000
pyruvate kinase 0.000
aspartate aminotransferase 0.000
TAT 0.000
chymotrypsin C 0.000
APC 0.000
isocitrate dehydrogenase 0.000
isocitrate dehydrogenase 0.000
MCS 0.000
gamma-glutamyl transpeptidase 0.000
matriptase 0.000
lactate dehydrogenase 0.000
thrombin 0.000
TDH 0.000
alkaline phosphatase 0.000
PRPP synthetase 0.000
CGT 0.000
S1 nuclease 0.000
arginase 0.000
matriptase 0.000
sulfiredoxin 0.000
TGT 0.000
glutathione reductase 0.000
methylenetetrahydrofolate reductase 0.000
UDP-glucuronosyltransferase 0.000
methylenetetrahydrofolate reductase 0.000
glutathione peroxidase 0.000
AST 0.000
catalase 0.000
GCA 0.000
GLO 0.000
sepiapterin reductase 0.000
DNA polymerase 0.000
Lod 0.000
AMP-activated kinase 0.000
aspartase 0.000
peroxiredoxin 0.000
DNA ligase 0.000
DNA ligase 0.000
glucocerebrosidase 0.000
superoxide dismutase 0.000
DNA methyltransferase 0.000
pantothenate kinase 0.000
ALA synthase 0.000
PKG 0.000
dihydroorotase 0.000
TdT 0.000
orotidine-5'-phosphate decarboxylase 0.000
AGT 0.000
phenylalanine hydroxylase 0.000
biotinidase 0.000
PMT 0.000
HCS 0.000
paraoxonase 0.000
cytidine deaminase 0.000
thromboplastin 0.000
focal adhesion kinase 0.000
heme oxygenase 0.000
RNA polymerase 0.000
cathepsin S 0.000
paraoxonase 0.000
phosphoglycerate kinase 0.000
thiopurine methyltransferase 0.000
isopeptidase 0.000
carbonic anhydrase 0.000
carboxypeptidase B 0.000
thymidine kinase 0.000
gamma-glutamylcysteine synthetase 0.000
endothelin-converting enzyme 0.000
6-phosphogluconate dehydrogenase 0.000
6-phosphogluconate dehydrogenase 0.000
DAT 0.000
NAT 0.000
3-hydroxyacyl-CoA dehydrogenase 0.000
PDH 0.000
type III procollagen 0.000
more...
Compound
Hemoglobin 0.025
HBB 0.012
iron 0.002
MCH 0.002
Hydroxyurea 0.000
DFO 0.000
DNA 0.000
Benin 0.000
CAA 0.000
Bantu 0.000
Cap 0.000
S 41 0.000
BTT 0.000
LCR 0.000
beta-Aminoisobutyric acid 0.000
Clin 0.000
TAA 0.000
HBA 0.000
Isopimpinellin 0.000
Desferal 0.000
Indicaxanthin 0.000
PMA 0.000
DPG 0.000
VPM 0.000
Busulfan 0.000
Dec 0.000
oxygen 0.000
DPG 0.000
2-pyridinecarbaldehyde 0.000
2,3-diphosphoglycerate 0.000
Tartar 0.000
DCIP 0.000
2-butoxyethanol 0.000
Complamin 0.000
5-Azacytidine 0.000
Asp 0.000
leucine 0.000
zinc 0.000
3-pyridinol 0.000
G11 0.000
Cilag 0.000
Novex 0.000
lysine 0.000
Phosphatidylserine 0.000
Diamant 0.000
Methylxanthine 0.000
Triptan 0.000
Angelicin 0.000
His 0.000
Hemin 0.000
Hemin 0.000
Hemin 0.000
Hemin 0.000
creatinine 0.000
Tetrahydrouridine 0.000
HC-toxin 0.000
TDT 0.000
AAT 0.000
DCI 0.000
Hemin 0.000
Ferrous sulfate 0.000
acetate 0.000
alanine 0.000
5-Aza-2'-deoxycytidine 0.000
cyclopropanecarboxylic acid 0.000
BMD 0.000
cyclopropanecarboxylic acid 0.000
glucose-6-phosphate 0.000
Heme 0.000
Trp-P-2 0.000
Gly 0.000
GAP 0.000
arginine 0.000
DHB 0.000
vitamin D 0.000
DHBA 0.000
Fast Blue B 0.000
GTP 0.000
TSH 0.000
TGT 0.000
more...