Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0039730 (
thalassemia
)
10,305
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
G-gamma globin
11.6
OR52Z1
11.6
OR51V1
11.6
Alpha-hemoglobin-stabilizing protein
11.6
OR52A4
11.6
OR52A5
11.6
OR51A1P
11.6
ARHGDIG
11.6
OR52A1
11.6
HBD/HBB
11.6
LARP2
11.6
beta globin variant
11.6
delta-globin chain
11.1
HBA2
10.9
mutant beta-globin
10.7
HOR5
10.6
Zeta-globin
10.6
delta globin
10.6
H3 histone, family 3A
10.6
Gamma globin
10.6
truncated beta-globin
10.6
HBA1
10.5
HBG2
10.5
beta globin chain
10.4
ATRX protein
10.4
delta-globin
10.3
HBB
10.3
HBS1L
10.3
alpha-2 globin
10.3
alpha 1 globin
10.2
gamma-globin chain
10.2
HBG1
10.2
alpha globin
10.2
G-gamma
10.0
ITFG3
10.0
PDA2
10.0
ZNF471
10.0
twisted gastrulation protein
10.0
hemoglobin alpha 2
10.0
ADP-ribosylation factor guanine nucleotide-exchange factor 2
10.0
BCL11A
9.9
Beta globin
9.8
Beta-globin
9.8
beta globin
9.7
DEP domain containing 5
9.6
gamma globin
9.5
gamma-globin
9.5
I-1
9.5
beta-globin
9.4
LUC7L
9.4
alpha 2 globin
9.4
X-linked protein
9.4
OTT3
9.3
FREM3
9.3
alpha-1 globin
9.3
SLC35D3
9.3
DAXX protein
9.2
XNP
9.1
ARIP4
9.0
MIER1
9.0
RAB11 family interacting protein 3
9.0
theta-1
8.9
mitochondrial intermediate peptidase
8.9
ATRX
8.9
KLF1
8.8
HBD
8.8
FAM122A
8.8
toll interacting protein
8.8
PLAC4
8.8
zeta 2
8.7
X-linked)
8.7
USP38
8.6
TINO
8.4
BAIAP3
8.4
Hemoglobin beta
8.4
2'5' oligoadenylate synthetase
8.3
CTIP1
8.3
COMMD7
8.3
DAXX
8.2
hemoglobin beta
8.2
more...
Disease
Homozygous alpha thalassaemia
11.6
XLTT
11.6
Tonsillar actinomycosis
11.6
ATMDS
11.6
Acquired hemoglobinopathy
11.6
F thalassaemia
11.6
Pigment cirrhosis
11.6
Alpha thalassemia intermedia
11.6
thalassemia
11.6
HPFH deletion type
11.6
Other mental retardation
11.6
Other hemoglobinopathies
11.6
G6PD deficiency anemia
11.6
Hb-SD
11.6
Thalassemia intermedia
11.4
Hb-C disease
11.2
Hemoglobin E trait
11.2
Beta thalassaemia trait
11.1
Cardiac siderosis
11.0
thalassemia trait
10.9
sickle thalassemia
10.7
HPFH
10.7
thalassemia minor
10.6
alpha thalassemia
10.6
Homozygous hemoglobin E
10.6
Rietti-Greppi-Micheli
10.6
myelodysplastic anemia
10.6
HbS-HbD disease
10.6
Beta thalassemia minor
10.6
congenital blood disorder
10.6
beta thalassemia
10.6
hereditary anemia
10.5
hereditary persistence of fetal hemoglobin
10.4
Alpha thalassemia major
10.4
thalassemia major
10.3
HBB
10.3
HBB
10.3
HBB
10.3
Sickle cell thalassemia
10.3
X-linked alpha-thalassemia/mental retardation syndrome
10.1
hemoglobinopathies
10.1
Progression of rheumatoid arthritis
10.0
oligocythemia
10.0
Gurrieri syndrome
10.0
Beta thalassemia intermedia
10.0
Hepatic siderosis
9.8
Hb SC disease
9.8
acquired hemochromatosis
9.6
Splenic sequestration
9.6
Hemoglobin C trait
9.6
Chronic hemolytic anemia
9.3
Hepatic hemosiderosis
9.3
microcytic anemia
9.3
Microcytic hypochromic anemia
9.2
hypochromic anemia
9.1
splenoptosis
9.0
Smith-Fineman-Myers syndrome
9.0
iron overload
9.0
congenital anemia
8.9
ATRX
8.9
HBD
8.8
Neonatal anemia
8.8
CIID
8.8
Chronic iron overload
8.7
Chronic anemia
8.7
blood disorder
8.7
sickle cell disease
8.6
Renal hemosiderosis
8.6
Compensated hypothyroidism
8.6
congenital hemolytic anemia
8.4
pyruvate kinase deficiency
8.4
acute chest syndrome
8.3
dyserythropoietic anemia
8.3
hereditary spherocytosis
8.2
G6PD deficiency
8.1
hemosiderosis
8.0
Myeloid Leukemia
8.0
Southeast Asian ovalocytosis
8.0
Hydrops fetalis
7.9
Pythiosis
7.9
more...
Symptom
Reticulocytosis
7.6
Cutaneous anergy
7.3
splenomegaly
6.2
left upper quadrant pain
6.1
cardiovascular impairment
5.8
Organ failure
5.6
pallor
5.4
lumbar back pain
5.2
hepatosplenomegaly
5.2
paraparesis
4.6
hepatomegaly
4.6
non-productive cough
4.5
No adverse effect
4.3
generalized pain
4.0
Opposition
3.9
labored breathing
3.9
disturbed balance
3.8
stomach pain
3.6
bone pain
3.4
muscle rigidity
3.1
Scratch
3.0
asthenia
2.8
arthralgia
2.8
acute pain
2.6
Decreased activity
2.5
ankle pain
2.5
breath holding
2.5
hypoproteinemia
2.4
Gastrointestinal symptoms
2.4
Fluctuation
2.4
cyanosis
2.3
tingling
2.3
atypical chest pain
2.3
leg pain
2.2
shortness of breath
2.1
back pain
2.0
chest tightness
2.0
chills
1.9
epigastric pain
1.8
abdominal discomfort
1.8
thinning
1.7
dry skin
1.6
acute abdomen
1.6
numbness
1.6
fever of unknown origin
1.6
emaciation
1.5
eds
1.5
exertional dyspnea
1.4
lethargy
1.4
decreased appetite
1.4
masculinization
1.3
myalgia
1.2
tonic-clonic seizure
1.2
nausea
1.2
dizziness
1.2
bitter taste
1.1
snoring
1.1
dyspnea
1.1
physical appearance
1.0
wheezing
1.0
despair
0.9
enuresis
0.9
paresthesia
0.9
memory loss
0.8
abdominal pain
0.8
stigma
0.7
exhaustion
0.7
anorexia
0.6
chronic cough
0.6
regurgitation
0.6
chest pain
0.5
headache
0.5
tense
0.5
flank pain
0.5
Ill
0.5
acute stress
0.4
vomiting
0.3
dysuria
0.3
low back pain
0.3
discomfort
0.3
more...
Drug
Deferasirox
9.9
Methylhydrazine
8.6
Deferoxamine mesylate
8.1
Sodium phenylbutyrate
7.8
Hakka
7.3
Desferal
6.8
Atarax
6.8
Desferal
6.6
Glucose-6-Phosphate
6.3
AGG
6.0
TRM
5.9
Cellulose acetate
5.9
Benserazide
5.8
Lariam
5.8
VCR
5.6
Sonata
5.4
Epoetin alfa
5.3
CET
5.3
Ferrous sulfate
5.3
Phosphatidylserine
5.0
Sodium thiosulfate
5.0
Zoledronic acid
4.6
Ipriflavone
4.6
Fludarabine
4.3
Zoledronic acid
4.3
Colombo
4.2
Tenofovir disoproxil fumarate
4.2
Denosumab
4.1
TAT
4.1
Daclizumab
4.1
Epoetin alfa
3.9
DFP
3.7
Heme
3.7
CTM
3.7
Fansidar
3.7
Fansidar
3.6
Compound 9
3.6
Clodronate
3.6
Pyridoxal
3.6
Zmax
3.6
Antithrombin III
3.6
Cobalamin
3.5
Epoetin
3.5
TES
3.5
CTM
3.2
Luteinizing
3.1
Piracetam
3.1
Vorinostat
3.1
G418
3.1
Campath
3.0
Campath
3.0
SBT
3.0
TAC
2.9
CTT
2.9
Asn
2.8
Growth hormone
2.8
Finasteride
2.8
Emodin
2.7
Growth hormone
2.6
PFA
2.6
vitamin E
2.6
G-CSF
2.6
CTC
2.6
Dakar
2.5
Orphan
2.5
NAG
2.5
MDS
2.5
Activin
2.4
Emodin
2.4
BTC
2.4
CFT
2.4
DNase I
2.4
Vitamin B12
2.3
CTC
2.3
Vitamin E
2.2
Fluorescein
2.2
Trib
2.2
Kenyan
2.1
ACT
2.1
Camp
2.1
more...
Enzyme
chymotrypsin C
5.9
BMT
5.2
glucose-6-phosphate dehydrogenase
5.1
TDH
4.8
PRPP synthetase
4.7
matriptase
4.6
sulfiredoxin
4.6
endonuclease
4.5
CGT
4.4
MCS
4.3
matriptase
4.2
TGT
4.2
sepiapterin reductase
4.1
TAT
4.1
Lod
4.0
GLO
3.9
aspartase
3.9
pyruvate kinase
3.8
AMP-activated kinase
3.7
GCA
3.7
pantothenate kinase
3.6
isocitrate dehydrogenase
3.6
isocitrate dehydrogenase
3.4
dihydroorotase
3.4
methylenetetrahydrofolate reductase
3.4
methylenetetrahydrofolate reductase
3.3
orotidine-5'-phosphate decarboxylase
3.2
ALA synthase
3.2
S1 nuclease
3.1
glucocerebrosidase
3.1
UDP-glucuronosyltransferase
3.1
arginase
3.1
AGT
3.0
biotinidase
3.0
PMT
3.0
HCS
2.9
alanine aminotransferase
2.9
peroxiredoxin
2.8
DNA ligase
2.8
DNA ligase
2.8
phenylalanine hydroxylase
2.7
ERK
2.7
TdT
2.7
gamma-glutamyl transpeptidase
2.7
aspartate aminotransferase
2.7
cytidine deaminase
2.7
APC
2.6
cathepsin S
2.6
PKG
2.6
AST
2.6
thiopurine methyltransferase
2.5
isopeptidase
2.5
paraoxonase
2.4
glutathione reductase
2.4
carboxypeptidase B
2.3
DNA methyltransferase
2.3
endothelin-converting enzyme
2.3
NAT
2.2
3-hydroxyacyl-CoA dehydrogenase
2.2
PDH
2.2
type III procollagen
2.2
paraoxonase
2.1
gamma-glutamylcysteine synthetase
2.1
6-phosphogluconate dehydrogenase
2.1
6-phosphogluconate dehydrogenase
2.1
phosphoglycerate kinase
2.1
DAT
2.1
CEP
2.0
MDH
2.0
heme oxygenase
1.9
phosphoglucose isomerase
1.9
aspartate transcarbamylase
1.9
lactate dehydrogenase
1.8
MDH
1.8
PHD
1.8
sucrase-isomaltase
1.8
phosphorylase kinase
1.8
LasR
1.8
glutathione peroxidase
1.8
ferrochelatase
1.7
more...
Compound
S 41
10.6
HBB
10.3
Hemoglobin
9.2
beta-Aminoisobutyric acid
8.8
MCH
8.5
Isopimpinellin
8.3
BTT
8.1
Indicaxanthin
7.9
Hydroxyurea
7.5
DFO
7.1
2-pyridinecarbaldehyde
7.1
Bantu
7.0
CAA
6.8
Benin
6.8
Desferal
6.6
LCR
6.6
Tartar
6.6
Complamin
6.5
3-pyridinol
6.4
Cap
6.3
Novex
6.3
Diamant
6.2
Methylxanthine
6.2
Triptan
6.2
DCIP
6.2
Cilag
6.1
Angelicin
6.1
VPM
6.1
HBA
6.0
Tetrahydrouridine
5.9
HC-toxin
5.9
2-butoxyethanol
5.9
Busulfan
5.8
Ferrous sulfate
5.6
cyclopropanecarboxylic acid
5.5
cyclopropanecarboxylic acid
5.5
5-Azacytidine
5.4
TAA
5.4
DCI
5.4
DPG
5.3
G11
5.3
TDT
5.2
iron
5.2
Fast Blue B
5.1
Phosphatidylserine
5.0
Trp-P-2
5.0
2,3-diphosphoglycerate
4.9
uroporphyrin I
4.9
Hemin
4.9
Hemin
4.9
Hemin
4.9
Hemin
4.9
Ferric chloride
4.9
DPG
4.8
Hemin
4.7
Zinc protoporphyrin
4.7
G17
4.7
5-Aza-2'-deoxycytidine
4.7
DHB
4.7
HMBA
4.7
AAT
4.6
TGT
4.5
DHBA
4.4
Benzidine
4.4
COA
4.3
HMBA
4.3
Fructosamine
4.1
Thiotepa
4.1
Piceatannol
4.1
Isopaque
4.1
11-dehydro-thromboxane
4.0
PhIP
4.0
CDP-ethanolamine
3.9
Mithramycin
3.9
Pyruvate kinase
3.8
TIF
3.8
TCC
3.8
PMA
3.7
1,1,2-trichloroethane
3.7
GAP
3.7
more...