Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0039730 (thalassemia)
10,305 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein hemoglobin 2392 beta-globin 1022 ferritin 721 Sep 615 erythroid 549 Mol 408 HBB 303 gamma-globin 197 transferrin 187 HLA 180 melanin-concentrating hormone 164 beta globin 164 erythropoietin 157 alpha globin 141 endonuclease 134 methemoglobin 124 HBA2 118 X-linked 115 I-1 111 alpha-chain 101 ATRX 99 BCL11A 93 MRI 87 hemochromatosis 79 glucose-6-phosphate dehydrogenase 78 transferrin receptor 77 She 76 insulin 72 HBA1 71 delta-globin 70 CD34 65 ATR 60 MED 59 hereditary hemochromatosis 56 gamma globin 52 cryptic 49 AAG 49 gamma chain 46 ARMS 46 cystatin C 44 Hepcidin 43 histone 43 alkaline phosphatase 42 HBG2 40 HBD 39 polypeptide 39 MYB 38 thrombin 38 growth hormone 37 HFE 36 HBS1L 34 human leukocyte antigen 34 GTG 33 lactate dehydrogenase 33 cytokine 33 Ferritin 32 B12 32 prothrombin 31 collagen 31 aspartate aminotransferase 30 catalase 30 GSH 30 UTR 30 ATP 29 protein C 28 alanine aminotransferase 28 B19 27 DAXX 26 interferon 26 superoxide dismutase 25 G6PD 25 Rad 25 KLF1 25 telomeric 25 ATRX protein 24 glutathione peroxidase 24 ABO 24 osteocalcin 23 p53 23 beta globin chain 23 more...

Disease thalassemia 10305 sickle cell disease 1474 anemia 1365 iron overload 1012 hemoglobinopathies 948 thalassemia major 913 beta thalassemia 435 HBB 303 HBB 303 HBB 303 hemolytic anemia 302 iron deficiency 297 malaria 291 thalassemia trait 256 cancer 223 diabetes 191 mental retardation 166 mental retardation 164 alpha thalassemia 160 iron deficiency anemia 154 graft-versus-host disease 152 microcytic anemia 145 osteoporosis 130 hemochromatosis 128 hereditary persistence of fetal hemoglobin 127 myelodysplastic syndrome 124 G6PD deficiency 122 hepatitis C 119 heart failure 117 genetic disorder 112 thalassemia minor 111 hereditary spherocytosis 111 pulmonary hypertension 108 stroke 108 leukemia 104 West 100 ATRX 99 hepatitis B 95 hemosiderosis 89 HIV 85 cirrhosis 85 tumor 83 cystic fibrosis 82 aplastic anemia 82 hypothyroidism 81 blood disorder 75 hypogonadism 74 sepsis 74 hypochromic anemia 71 HPFH 70 hepatitis 69 abortion 68 cardiomyopathy 67 haemophilia 67 hereditary hemochromatosis 64 infectious diseases 64 gallstones 64 siderosis 64 thrombocytopenia 60 acute chest syndrome 58 spinal cord compression 57 immunodeficiency 55 hypertension 55 leg ulcers 54 sepsis 54 hypersplenism 49 chronic hepatitis 49 heart disease 48 hepatocellular carcinoma 46 Down syndrome 45 chronic myeloid leukemia 43 AIDS 42 bone disease 40 hypoparathyroidism 40 HBD 39 erythrocytosis 39 syndrome X 38 CAA 38 CAA 38 liver disease 38 more...

Symptom splenomegaly 227 pain 101 hepatosplenomegaly 51 hepatomegaly 45 pallor 34 headache 26 seizures 24 paraparesis 22 diarrhea 21 fatigue 19 dyspnea 19 anesthesia 18 abdominal pain 17 nausea 17 back pain 16 arthralgia 16 weakness 15 vomiting 13 thinning 12 bone pain 11 discomfort 9 discomfort 9 acute pain 8 chest pain 8 anorexia 7 dizziness 7 stigma 7 exhaustion 7 respiratory distress 7 shortness of breath 7 asthenia 6 cyanosis 6 lethargy 5 Ill 5 numbness 5 analgesia 5 chills 5 myalgia 5 angina 4 low back pain 4 epigastric pain 4 overweight 4 regurgitation 4 collapse 4 leg pain 3 cough 3 left upper quadrant pain 3 syncope 3 paresthesia 3 hypothermia 3 muscle rigidity 3 ataxia 3 erythema 3 Reticulocytosis 3 wheezing 3 acute abdomen 3 exertional dyspnea 3 No adverse effect 2 non-productive cough 2 abdominal discomfort 2 acute stress 2 hypoproteinemia 2 tremor 2 masculinization 2 fever of unknown origin 2 hypotonia 2 cardiovascular impairment 2 tingling 2 memory loss 2 stomach pain 2 snoring 2 physical appearance 1 tense 1 generalized pain 1 constipation 1 Decreased activity 1 starvation 1 chronic cough 1 sleepiness 1 dysarthria 1 more...

Drug Deferasirox 60 vitamin E 34 lysine 30 Asn 27 ascorbate 27 VCR 25 Cardiovasc 19 Dermatol 18 AGG 16 DNase I 14 Heme 13 TAT 13 Desferal 10 G-CSF 10 Gel 9 ROS 8 Desferal 8 FAD 7 Growth hormone 7 Phosphatidylserine 7 TRM 7 Leaf 6 G418 6 Growth hormone 6 ROC 6 PTH 5 Cellulose acetate 5 CSF 5 Vitamin E 5 IFN-gamma 5 Kenyan 5 Fluorescein 5 Zoledronic acid 5 Mutagen 5 NADH 4 Epoetin alfa 4 Fluorescein 4 MDS 4 Zoledronic acid 4 Hakka 4 CTX 4 THF 4 Dakar 4 NAG 4 TAC 4 DFP 4 Fludarabine 3 Luteinizing 3 Activin 3 ACT 3 Glutathione 3 Denosumab 3 Nitric Oxide 3 Nephron 3 Asthma 3 Biopolymers 3 Nephron 3 pyridoxal phosphate 3 AZT 2 Colombo 2 PTC 2 niacin 2 Alanine 2 CTC 2 Bayer 2 Sodium phenylbutyrate 2 Antithrombin III 2 HCG 2 Vitamin B12 2 PFA 2 Campath 2 Deferoxamine mesylate 2 CET 2 Portal 2 AZT 2 Monit 2 ampicillin 2 Campath 2 CTC 2 TES 2 more...

Enzyme ERK 203 endonuclease 134 glucose-6-phosphate dehydrogenase 86 alanine aminotransferase 65 aspartate aminotransferase 45 alkaline phosphatase 42 thrombin 36 catalase 35 lactate dehydrogenase 34 APC 33 BMT 32 superoxide dismutase 30 glutathione peroxidase 24 pyruvate kinase 23 focal adhesion kinase 19 gamma-glutamyl transpeptidase 19 DNA polymerase 18 ATPase 17 peroxidase 17 glutathione reductase 16 RNA polymerase 16 protein kinase 14 TAT 13 isocitrate dehydrogenase 12 mitogen-activated protein kinase 12 AST 12 reverse transcriptase 12 isocitrate dehydrogenase 12 luciferase 11 trypsin 10 thromboplastin 10 arginase 10 S1 nuclease 10 UDP-glucuronosyltransferase 9 DNA methyltransferase 8 methylenetetrahydrofolate reductase 7 NO synthase 7 methylenetetrahydrofolate reductase 7 transcriptase 6 thymidine kinase 6 DNA ligase 6 DNA ligase 6 peroxiredoxin 6 carbonic anhydrase 6 acid phosphatase 6 heme oxygenase 5 caspase-3 5 RNase 5 RNase 5 MCS 5 PKG 5 glutathione S-transferase 4 protein kinase C 4 TdT 4 AMP-activated protein kinase 4 adenosine deaminase 4 glucocerebrosidase 4 renin 4 adenosine deaminase 4 calcineurin 4 hexokinase 4 ACE 4 xanthine oxidase 4 tissue plasminogen activator 4 ceruloplasmin 4 proteasome 4 CGT 3 ribonuclease 3 5'-nucleotidase 3 TGT 3 paraoxonase 3 AMPK 3 GCA 3 ribonuclease 3 ACS 3 matriptase 3 creatine kinase 3 beta-galactosidase 3 phosphoglycerate kinase 3 ALA synthase 3 more...

Compound iron 1659 DNA 1447 Hemoglobin 1366 Clin 810 Dec 630 HBB 303 oxygen 255 MCH 164 calcium 100 zinc 96 glucose 91 acetate 88 lysine 87 leucine 80 His 79 Hydroxyurea 68 creatinine 66 arginine 66 alanine 65 sodium 62 Asp 61 phosphate 59 DFO 59 PMA 53 Benin 53 nitric oxide 43 Gly 40 water 39 CAA 38 Cap 37 urea 37 copper 36 vitamin D 34 GTP 34 hydrogen 34 GSH 32 GSH 32 threonine 32 ATP 29 tyrosine 27 LCR 25 TSH 24 Bantu 24 TAA 23 potassium 22 methionine 22 SDS 21 proline 20 cysteine 20 EDTA 20 Cardiol 20 EDTA 20 sulfate 19 phosphorus 18 CO2 18 H2O2 18 Ile 17 DPG 16 DPG 16 Phe 15 TEM 15 ADP 15 HBA 14 Pac 14 isopropanol 14 nitrogen 14 DEAE 14 glutamic acid 13 2,3-diphosphoglycerate 13 BMD 13 Tris 13 serine 13 glucose-6-phosphate 13 Heme 13 TRH 12 Thyroid 12 glutamine 12 Tris 12 valine 12 silver 12 more...

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