Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0039730 (thalassemia)
 10,305 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
LARP2 11.6
OR52A4 11.6
HBD/HBB 11.6
ARHGDIG 11.6
G-gamma globin 11.6
OR52A1 11.6
OR51A1P 11.6
OR52A5 11.6
OR52Z1 11.6
OR51V1 11.6
beta globin variant 11.6
Alpha-hemoglobin-stabilizing protein 11.6
delta-globin chain 11.1
HBA2 10.9
mutant beta-globin 10.7
Gamma globin 10.6
Zeta-globin 10.6
delta globin 10.6
truncated beta-globin 10.6
HOR5 10.6
H3 histone, family 3A 10.6
HBA1 10.5
HBG2 10.5
beta globin chain 10.4
ATRX protein 10.4
delta-globin 10.3
HBB 10.3
HBS1L 10.3
alpha-2 globin 10.3
alpha 1 globin 10.2
gamma-globin chain 10.2
HBG1 10.2
alpha globin 10.2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 10.0
twisted gastrulation protein 10.0
G-gamma 10.0
ZNF471 10.0
ITFG3 10.0
hemoglobin alpha 2 10.0
PDA2 10.0
more...
Disease
Other mental retardation 11.6
thalassemia 11.6
G6PD deficiency anemia 11.6
HPFH deletion type 11.6
Hb-SD 11.6
Tonsillar actinomycosis 11.6
XLTT 11.6
Acquired hemoglobinopathy 11.6
ATMDS 11.6
Pigment cirrhosis 11.6
Homozygous alpha thalassaemia 11.6
Other hemoglobinopathies 11.6
F thalassaemia 11.6
Alpha thalassemia intermedia 11.6
Thalassemia intermedia 11.4
Hemoglobin E trait 11.2
Hb-C disease 11.2
Beta thalassaemia trait 11.1
Cardiac siderosis 11.0
thalassemia trait 10.9
sickle thalassemia 10.7
HPFH 10.7
thalassemia minor 10.6
alpha thalassemia 10.6
myelodysplastic anemia 10.6
Homozygous hemoglobin E 10.6
Rietti-Greppi-Micheli 10.6
congenital blood disorder 10.6
Beta thalassemia minor 10.6
HbS-HbD disease 10.6
beta thalassemia 10.6
hereditary anemia 10.5
hereditary persistence of fetal hemoglobin 10.4
Alpha thalassemia major 10.4
thalassemia major 10.3
HBB 10.3
HBB 10.3
HBB 10.3
Sickle cell thalassemia 10.3
X-linked alpha-thalassemia/mental retardation syndrome 10.1
more...
Symptom
Reticulocytosis 7.6
Cutaneous anergy 7.3
splenomegaly 6.2
left upper quadrant pain 6.1
cardiovascular impairment 5.8
Organ failure 5.6
pallor 5.4
lumbar back pain 5.2
hepatosplenomegaly 5.2
paraparesis 4.6
hepatomegaly 4.6
non-productive cough 4.5
No adverse effect 4.3
generalized pain 4.0
Opposition 3.9
labored breathing 3.9
disturbed balance 3.8
stomach pain 3.6
bone pain 3.4
muscle rigidity 3.1
Scratch 3.0
asthenia 2.8
arthralgia 2.8
acute pain 2.6
Decreased activity 2.5
ankle pain 2.5
breath holding 2.5
hypoproteinemia 2.4
Gastrointestinal symptoms 2.4
Fluctuation 2.4
cyanosis 2.3
tingling 2.3
atypical chest pain 2.3
leg pain 2.2
shortness of breath 2.1
back pain 2.0
chest tightness 2.0
chills 1.9
epigastric pain 1.8
abdominal discomfort 1.8
more...
Drug
Deferasirox 9.9
Methylhydrazine 8.6
Deferoxamine mesylate 8.1
Sodium phenylbutyrate 7.8
Hakka 7.3
Desferal 6.8
Atarax 6.8
Desferal 6.6
Glucose-6-Phosphate 6.3
AGG 6.0
TRM 5.9
Cellulose acetate 5.9
Benserazide 5.8
Lariam 5.8
VCR 5.6
Sonata 5.4
Epoetin alfa 5.3
CET 5.3
Ferrous sulfate 5.3
Phosphatidylserine 5.0
Sodium thiosulfate 5.0
Zoledronic acid 4.6
Ipriflavone 4.6
Fludarabine 4.3
Zoledronic acid 4.3
Colombo 4.2
Tenofovir disoproxil fumarate 4.2
Denosumab 4.1
TAT 4.1
Daclizumab 4.1
Epoetin alfa 3.9
DFP 3.7
Heme 3.7
CTM 3.7
Fansidar 3.7
Fansidar 3.6
Compound 9 3.6
Clodronate 3.6
Pyridoxal 3.6
Zmax 3.6
more...
Enzyme
chymotrypsin C 5.9
BMT 5.2
glucose-6-phosphate dehydrogenase 5.1
TDH 4.8
PRPP synthetase 4.7
matriptase 4.6
sulfiredoxin 4.6
endonuclease 4.5
CGT 4.4
MCS 4.3
matriptase 4.2
TGT 4.2
sepiapterin reductase 4.1
TAT 4.1
Lod 4.0
GLO 3.9
aspartase 3.9
pyruvate kinase 3.8
AMP-activated kinase 3.7
GCA 3.7
pantothenate kinase 3.6
isocitrate dehydrogenase 3.6
isocitrate dehydrogenase 3.4
dihydroorotase 3.4
methylenetetrahydrofolate reductase 3.4
methylenetetrahydrofolate reductase 3.3
orotidine-5'-phosphate decarboxylase 3.2
ALA synthase 3.2
S1 nuclease 3.1
glucocerebrosidase 3.1
UDP-glucuronosyltransferase 3.1
arginase 3.1
AGT 3.0
biotinidase 3.0
PMT 3.0
HCS 2.9
alanine aminotransferase 2.9
peroxiredoxin 2.8
DNA ligase 2.8
DNA ligase 2.8
more...
Compound
S 41 10.6
HBB 10.3
Hemoglobin 9.2
beta-Aminoisobutyric acid 8.8
MCH 8.5
Isopimpinellin 8.3
BTT 8.1
Indicaxanthin 7.9
Hydroxyurea 7.5
DFO 7.1
2-pyridinecarbaldehyde 7.1
Bantu 7.0
CAA 6.8
Benin 6.8
Desferal 6.6
LCR 6.6
Tartar 6.6
Complamin 6.5
3-pyridinol 6.4
Cap 6.3
Novex 6.3
Diamant 6.2
Methylxanthine 6.2
Triptan 6.2
DCIP 6.2
Angelicin 6.1
Cilag 6.1
VPM 6.1
HBA 6.0
Tetrahydrouridine 5.9
HC-toxin 5.9
2-butoxyethanol 5.9
Busulfan 5.8
Ferrous sulfate 5.6
cyclopropanecarboxylic acid 5.5
cyclopropanecarboxylic acid 5.5
5-Azacytidine 5.4
TAA 5.4
DCI 5.4
DPG 5.3
more...