Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0039730 (
thalassemia
)
10,305
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
hemoglobin
2392
beta-globin
1022
ferritin
721
Sep
615
erythroid
549
Mol
408
HBB
303
gamma-globin
197
transferrin
187
HLA
180
beta globin
164
melanin-concentrating hormone
164
erythropoietin
157
alpha globin
141
endonuclease
134
methemoglobin
124
HBA2
118
X-linked
115
I-1
111
alpha-chain
101
more...
Disease
thalassemia
10305
sickle cell disease
1474
anemia
1365
iron overload
1012
hemoglobinopathies
948
thalassemia major
913
beta thalassemia
435
HBB
303
HBB
303
HBB
303
hemolytic anemia
302
iron deficiency
297
malaria
291
thalassemia trait
256
cancer
223
diabetes
191
mental retardation
166
mental retardation
164
alpha thalassemia
160
iron deficiency anemia
154
more...
Symptom
splenomegaly
227
pain
101
hepatosplenomegaly
51
hepatomegaly
45
pallor
34
headache
26
seizures
24
paraparesis
22
diarrhea
21
dyspnea
19
fatigue
19
anesthesia
18
abdominal pain
17
nausea
17
arthralgia
16
back pain
16
weakness
15
vomiting
13
thinning
12
bone pain
11
more...
Drug
Deferasirox
60
vitamin E
34
lysine
30
Asn
27
ascorbate
27
VCR
25
Cardiovasc
19
Dermatol
18
AGG
16
DNase I
14
TAT
13
Heme
13
G-CSF
10
Desferal
10
Gel
9
Desferal
8
ROS
8
FAD
7
Growth hormone
7
Phosphatidylserine
7
more...
Enzyme
ERK
203
endonuclease
134
glucose-6-phosphate dehydrogenase
86
alanine aminotransferase
65
aspartate aminotransferase
45
alkaline phosphatase
42
thrombin
36
catalase
35
lactate dehydrogenase
34
APC
33
BMT
32
superoxide dismutase
30
glutathione peroxidase
24
pyruvate kinase
23
gamma-glutamyl transpeptidase
19
focal adhesion kinase
19
DNA polymerase
18
ATPase
17
peroxidase
17
glutathione reductase
16
more...
Compound
iron
1659
DNA
1447
Hemoglobin
1366
Clin
810
Dec
630
HBB
303
oxygen
255
MCH
164
calcium
100
zinc
96
glucose
91
acetate
88
lysine
87
leucine
80
His
79
Hydroxyurea
68
arginine
66
creatinine
66
alanine
65
sodium
62
more...