Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0039483 (giant cell arteritis)
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Human Gene/Protein
GCA 13.3
KLEIP 11.3
GCA1 11.3
C8orf13 11.3
HLA-DR beta 1 chain 11.0
CCDC14 11.0
ARHGAP27 10.7
cysteine-tRNA synthetase 10.7
MRPL23 10.5
DUSG 10.3
lymphoid-restricted membrane protein 10.3
grancalcin 10.2
hBUB3 10.1
polyadenylate binding protein 10.0
leukocyte antigen class II 10.0
ZFP161 10.0
PION 10.0
ZC3H11A 10.0
GTF2H2 9.8
GPR135 9.8
GCG 9.7
GTA 9.7
RASSF3 9.6
HKR1 9.5
PAB2 9.5
SR14 9.5
TRIT1 9.4
STARD5 9.4
GP330 9.3
rps13 9.3
TGC 9.2
voltage-gated sodium channel alpha subunit 9.2
KLHL20 9.1
CGT 9.1
cysteinyl-tRNA synthetase 9.1
Jaw1 9.0
STARD4 9.0
RASSF4 8.9
PABP2 8.8
C20orf54 8.6
COL27A1 8.6
P4HA2 8.5
GAA 8.5
hBUB1 8.5
DQw 8.4
AgX 8.3
PURA 8.3
RASSF6 8.3
GCT 8.3
SRm160 8.2
Lipoyl synthase 8.2
HSA3 8.2
TCC 8.2
ribosomal protein S11 8.1
PABPN1 8.1
CGA 8.1
HLA-DRB1*04 8.1
GTT 8.0
SRP14 8.0
DEFB1 8.0
IPAF 8.0
RAB11A 8.0
HLA-B*5801 8.0
RAB5A 7.9
GCP2 7.9
MED15 7.9
CBS protein 7.9
FOXE3 7.8
CAT-3 7.8
HLA-B39 7.8
CAC 7.7
DORA 7.6
nuclear autoantigen 7.6
HLA-DR molecule 7.6
forkhead protein 7.6
GNN 7.6
CCA 7.5
CYB 7.5
AGT 7.5
GUA 7.4
more...
Disease
giant cell arteritis 13.3
Arteritic ischemic optic neuropathy 13.3
TBG-A 12.3
polymyalgia rheumatica 12.1
Pulmonary arteritis 11.7
Primary systemic vasculitis 11.2
Oculomotor nerve paresis 11.0
Brain stem infarction 11.0
Nonarteritic ischemic optic neuropathy 11.0
Superficial phlebitis 10.7
Choroidal ischemia 10.7
Anterior ischemic optic neuropathy 10.5
Giant cell reaction 10.5
Ocular ischemic syndrome 10.3
Mesenteric vasculitis 10.3
Classic polyarteritis nodosa 10.3
Aortic aneurysm and dissection 10.3
ischemic optic neuropathy 10.2
Takayasu 10.1
ASMD 10.1
Pulmonary artery thrombosis 10.1
Mononeuritis multiplex 10.1
Listeria sepsis 10.0
Corneal decompensation 10.0
Cerebral vasculitis 9.9
Granulomatous angiitis 9.9
Elastolysis 9.9
aortitis 9.9
shoulder capsulitis 9.8
Syphilitic aortitis 9.7
Foster-Kennedy syndrome 9.7
ACCCA 9.7
Posterior ischemic optic neuropathy 9.6
Preleukemia 9.6
Pulmonary vasculitis 9.5
Hollenhorst 9.5
Phlyctenular keratoconjunctivitis 9.5
Painful ophthalmoplegia 9.4
polyarteritis nodosa 9.3
Central retinal artery occlusion 9.2
Oculopharyngeal muscular dystrophy 9.2
Branch retinal artery occlusion 9.2
Bilateral blindness 9.1
Herpes simplex 1 9.1
Inflammation of the central nervous system 9.0
Hypertrophic pachymeningitis 9.0
claudication 9.0
Coronary arteritis 9.0
Horton 8.9
Carotidynia 8.9
migratory arthritis 8.8
Sinus thrombosis 8.8
Necrotizing arteritis 8.8
Churg-Strauss syndrome 8.8
amaurosis 8.8
autoimmune vasculitis 8.7
Stauffer's syndrome 8.7
perineuritis 8.7
Cogan's syndrome 8.6
cervical arthritis 8.6
Primary Sjogren's syndrome 8.5
RS3PE syndrome 8.5
Wegener's granulomatosis 8.4
vasculitis 8.4
Cryoglobulinemic vasculitis 8.4
Primary antiphospholipid syndrome 8.3
unilateral blindness 8.3
Cutaneous vasculitis 8.2
GCT 8.2
TCC 8.2
Tracheal rupture 8.2
Rheumatoid vasculitis 8.1
Occipital neuralgia 8.1
ALS4 8.1
BRCAX 8.0
CRV 8.0
optic disc atrophy 7.9
Cervical radiculopathy 7.9
Charles Bonnet syndrome 7.8
low tension glaucoma 7.7
more...
Symptom
Arm claudication 13.3
Temporal headache 13.3
polymyalgia 12.0
Referred otalgia 11.7
feeling of malaise 10.5
Morning headache 10.0
Amaurosis fugax 10.0
Roth spots 9.1
glossodynia 9.1
jaw pain 8.9
Multiple symptoms 8.5
fever of unknown origin 8.2
Ortner's syndrome 7.8
sialectasis 7.8
Visual symptoms 7.5
General symptoms 7.4
Flare 6.8
non-productive cough 6.7
eye pain 6.7
astasia 6.3
facial droop 6.3
headache 6.2
orofacial pain 6.2
otalgia 6.1
ophthalmoplegia 6.0
limb pain 5.9
night sweats 5.9
myalgia 5.8
peri-menopausal 5.8
facial pain 5.8
generalized pain 5.7
blurred vision 5.6
Cushingoid 5.5
Cushingoid 5.5
ACHE 5.4
metamorphopsia 5.3
neuralgia 5.3
Ill 5.3
visual hallucination 5.1
hyperemesis 5.0
persistent cough 5.0
asthenia 4.9
Physical findings 4.9
meningism 4.9
neck pain 4.8
hoarseness 4.8
Tenderness 4.7
decreased appetite 4.7
muscle stiffness 4.6
dysarthria 4.6
pallor 4.6
anorexia 4.4
Halo 4.4
arm pain 4.3
hyperesthesia 4.2
eds 4.2
sore throat 4.2
productive cough 4.1
pleuritic chest pain 4.1
arthralgia 4.1
dental pain 4.0
neck stiffness 4.0
atypical chest pain 4.0
drooling 3.9
forgetfulness 3.9
chronic cough 3.9
shoulder pain 3.8
photophobia 3.7
hemiplegia 3.6
intestinal bleeding 3.6
wrist pain 3.5
livedo 3.5
cough 3.5
vertigo 3.5
muscle cramps 3.5
paraparesis 3.4
dysesthesia 3.4
fatigue 3.4
paresis 3.4
Stiffness 3.3
more...
Drug
Tocilizumab 8.9
CTT 8.4
AGG 7.7
Sulla 7.3
Prednisone 7.3
TAC 7.2
Japanese encephalitis vaccine 7.2
Naprosyn 7.0
CTC 6.9
Deflazacort 6.9
TTC 6.9
CTA 6.7
Abatacept 6.7
Imuran 6.6
CTC 6.6
ACT 6.6
Poudre 6.4
Etodolac 6.3
GNA 6.2
Avonex 6.1
Ipilimumab 5.6
Anakinra 5.3
Mezlocillin 5.2
Prednisolone 5.1
TAT 4.9
Filgrastim 4.8
Filgrastim 4.6
Methylprednisolone 4.4
CVA 4.4
EHDP 4.3
MTC 4.3
Iloprost 4.2
Tuberculin 4.1
Rituximab 3.8
Camp 3.8
CIA 3.7
Alanine 3.4
Fluorescein 3.4
TAK 3.3
Doxycycline 3.2
Capsicum 3.1
Vitamin B12 3.0
Nitric Oxide 2.9
Fluorescein 2.9
IL-1ra 2.9
Gleevec 2.8
Ranitidine 2.6
Acacia 2.6
Ginseng 2.6
Bevacizumab 2.5
NaI 2.4
NaI 2.4
NaI 2.4
NaI 2.4
p75 2.4
Asn 2.3
-deoxyadenosine 2.3
ENT 2.2
Paraffin 2.2
Imatinib 2.0
pyridoxal phosphate 2.0
Spectrum 1.9
ETS 1.9
G-CSF 1.9
AZT 1.9
Bifidobacterium 1.8
AZT 1.7
ADM 1.7
IFN-gamma 1.6
IL-2 1.4
Glucagon 1.4
MAP 1.3
Spectrum 1.3
Leaf 1.2
CSF 1.2
nitroglycerin 1.2
Albumin 1.0
Glutathione 0.9
FAD 0.8
Cardiovasc 0.8
more...
Enzyme
GCA 13.1
cysteinyl-tRNA synthetase 9.2
CGT 8.9
proteinase-3 7.4
AGT 7.3
TGT 7.1
isopentenyltransferase 6.8
GAR 6.3
neutrophil collagenase 5.7
RNase PH 5.6
ancrod 5.5
bile salt hydrolase 5.3
penicillin acylase 5.0
TAT 4.9
ACAT 4.8
PMT 4.6
acylase 4.5
lactic acid dehydrogenase 4.4
STK11 4.4
lactic acid dehydrogenase 4.4
CYP7A1 4.3
O-GlcNAc transferase 4.3
cystathionine gamma-lyase 4.2
CYP27A1 4.2
gamma-glutamyl transpeptidase 4.1
serine hydroxymethyltransferase 4.1
prenyltransferase 4.1
polynucleotide kinase 3.9
urease 3.9
CEP 3.7
lactic acid dehydrogenase 3.7
methionine synthase 3.6
methionine synthase 3.4
3beta-hydroxysteroid dehydrogenase 3.4
CEP 3.2
guanylate cyclase 3.0
tissue kallikrein 3.0
elastase 2.9
RNase P 2.9
purine nucleoside phosphorylase 2.8
Alternating 2.7
aspartate aminotransferase 2.6
PTA 2.6
glycerol-3-phosphate dehydrogenase 2.5
cathepsin G 2.5
glycerol-3-phosphate dehydrogenase 2.5
cholinesterase 2.5
thermolysin 2.4
glutaminase 2.4
PRE 2.4
cholesterol acyltransferase 2.3
matrix metalloproteinase 2 2.1
pectinase 2.0
DNA methyltransferase 2.0
PKG 2.0
hypoxanthine-guanine phosphoribosyltransferase 2.0
deaminase 2.0
alkaline phosphatase 1.9
MDP 1.9
DNA ligase 1.9
DNA ligase 1.9
thyroid peroxidase 1.7
AMPK 1.7
STR 1.6
peroxidase 1.6
granzyme B 1.6
aldose reductase 1.6
MMP-3 1.5
aldolase 1.5
S1 nuclease 1.4
catalase 1.4
endonuclease 1.4
DNase 1.4
neutrophil elastase 1.3
APC 1.3
DNA polymerase 1.2
glyceraldehyde-3-phosphate dehydrogenase 1.2
glyceraldehyde-3-phosphate dehydrogenase 1.2
MDR 1.2
topoisomerase 1.1
more...
Compound
6,7-Dimethyllumazine 11.7
3-Methylxanthine 10.1
Gallocyanin 10.0
Alloxazine 9.8
Alloxazine 9.8
Zopolrestat 9.0
5-Bromouracil 9.0
Nogalamycin 8.4
TCC 8.1
TCN 8.0
D-glucuronate 7.8
ANCA 7.6
Glycocholic acid 7.5
TTA 7.4
TGT 7.4
CAA 7.4
Gum arabic 7.3
Ergotamine 7.2
AAT 7.2
ATC 7.1
ATC 7.0
GGG 7.0
Deoxyuridine 6.7
Prednisone 6.6
TTC 6.6
Tauroursodeoxycholic acid 6.6
GAR 6.5
Tuftsin 6.4
ATA 6.4
AG-3 6.4
CCC 6.2
CCC 6.2
Lithocholic acid 6.2
Sorbinil 6.1
Azathioprine 6.1
AAA 6.1
DCA 5.7
DCA 5.7
PAN 5.6
Relaxant 5.5
Isoflavone 5.4
Methotrexate 5.4
Prednisolone 5.3
A 71 5.3
Ergot 5.3
MoSe2 5.3
UGA 5.2
Cyanine 5.2
SSH 5.2
MnO4 5.1
OCTA 5.1
methylguanosine 5.1
TEP 5.0
TCA 5.0
Thiabendazole 5.0
MSL 5.0
Leflunomide 4.9
TAA 4.9
MPA 4.9
MPA 4.9
MPA 4.8
HBB 4.8
PMT 4.6
CsI 4.6
Methylprednisolone 4.6
SVC 4.4
Nodular 4.4
Hydroxychloroquine 4.4
DOCA 4.3
Eosin 4.3
MTC 4.3
Valine 4.2
Cysteamine 4.2
acrylonitrile 4.2
AF-2 4.2
fMet 4.1
MEGA 4.1
Eosin 4.0
Etanercept 4.0
CAT 3.8
more...