Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0039483 (
giant cell arteritis
)
3,204
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Renal involvement is unusual in giant cell (temporal) arteritis (
GCA
). Microscopic hematuria and minimal proteinuria responsive to steroid therapy have been described as the most frequent renal alterations. The nephrotic syndrome in
GCA
has been rarely reported. We describe 2 cases of
GCA
with nephrotic syndrome, one at the time of diagnosis, the other 2 years after treatment. Percutaneous renal biopsy in both cases disclosed secondary
renal amyloidosis
confirmed by permanganate sensitivity and immunohistochemical analysis. To our knowledge, cases of
GCA
and secondary amyloidosis have not been reported.
...
PMID:Giant cell (temporal) arteritis and secondary renal amyloidosis: report of 2 cases. 955 98