Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0039483 (giant cell arteritis)
3,204 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A patient with biopsy proven temporal arteritis/polymyalgia rheumatica and erosive rheumatoid arthritis is presented. Only 15 such patients have previously been documented in the literature. The coexistence has been thought to be extremely infrequent, but could merely by chance appear in far more patients than previously reported.
Clin Rheumatol 1984 Dec
PMID:Coexistence of temporal arteritis/polymyalgia rheumatica and rheumatoid arthritis. 652 88

An 83 year old female presenting with a symmetrical peripheral polyarthritis resembling rheumatoid arthritis, subsequently developed biopsy-proven temporal arteritis. This case report draws attention to this uncommon presentation of temporal arteritis and briefly reviews common presenting features of this condition.
Aust N Z J Med 1983 Dec
PMID:Temporal arteritis presenting as a symmetrical peripheral polyarthritis. 658 55

Peripheral T cell populations were investigated in 35 patients suffering from polymyalgia rheumatica. The total number of T cells was low compared with those of a control group of similar age (P less than 10(-3). This decrease was demonstrated by using both classic E-rosette and monoclonal antibody techniques (OKT3, and OKT4 + OKT8) and was shown to be secondary to a selective T8 defect (P less than 10(-9). There was no correlation between the decrease in T8 (a cytotoxic suppressor T cell subset) and steroid therapy, disease activity, and temporal arteritis, nor between this decrease and the T gamma percentage and the presence of circulating immune complexes (CIC). The T gamma cell percentage was low in the patient group (P less than 10(-5) and correlated with the presence of detectable CIC (P less than 0.05). In contrast to the T8 and T gamma defects, concanavalin A-stimulated cells from 5 selected patients were found capable of suppressing in vitro anti-trinitrophenyl response. This suppression was found in both autologous and allogeneic experiments. From these data one can assume that an immune anomaly (T8 defect) could be the origin of CIC and the disease occurrence.
Arthritis Rheum 1983 Dec
PMID:Decrease of the OKT8 positive T cell subset in polymyalgia rheumatica. Lack of correlation with disease activity. 660 32

On the basis of some cases of presumable giant cell arteritis, which were diagnosed and treated in a nursing home, the polymorphous character of this affection is emphasized. The author poses that biopsies of the temporal artery--certainly with elderly people--shouldn't be regarded as an absolute necessity and he refers in this context to the discussion held about it in the Dutch Magazine of Medicine (Nederlands Tijdschrift voor Geneeskunde, 126, 1982, 14, p. 636-637). It is remarkable in this discussion that advocates of the possibly even double-sided temporal biopsies (!) refer to the criteria of the Mayo Clinics (1978), which on further consideration, don't seem to be quite sound and, to say the least of it, don't very much take into account the localization of the arterial lesions outside the well-known ones. Several other authors appear to take full account of the variant and masked forms and have their doubts about the efficiency of the temporal artery biopsy. Where giant cell arteritis concerns mostly elderly people and the geriatric approach and solution of this and other medical problems in general sometimes are contrary to the current 'formal-clinical' attitude, the author thought it right to propose an alternative for the elderly advances in years: the trial of steroid therapy, keeping a conscientious control on the clinical picture and the biochemical symptoms.
Tijdschr Gerontol Geriatr 1983 Dec
PMID:[Diagnosis ex juvantibus-- an observation on giant cell arteritis]. 665 29

Three cases of giant cell arteritis that developed in patients with known seropositive rheumatoid arthritis are described. The coexistence of these 2 conditions has been felt to be unusual. The diagnostic difficulties encountered when 2 such inflammatory conditions coexist are discussed.
J Rheumatol 1983 Dec
PMID:The coexistence of rheumatoid arthritis and giant cell arteritis. 666 4

Isolated aneurysm of the iliac artery is considered to be a rare disorder, although iliac aneurysm associated with abdominal aortic aneurysm is more common. Its clinical diagnosis is difficult, because symptoms are absent if an aneurysm is small, and because symptoms often mimic urogenital, neurological or gastrointestinal diseases if an aneurysm grows large without rupture. We reported a 40-year-old woman with isolated aneurysm of the left external iliac artery caused by giant cell arteritis, and surgically treated with success.
Nihon Geka Gakkai Zasshi 1983 Dec
PMID:[Isolated aneurysm of the external iliac artery caused by non-specific angiitis]. 667 84

The polyalgia rheumatica, which appears in one part of the patients together with a giant cell arteritis of the region of shoulder girdle and pelvic girdle. Also intensive temporal artery, is manifest with severe pains of their headache may be dominant in the disease. Observations on 14 own patients who belong to this picture of the disease confirm the initially existing and under glucocorticoids rapidly reversible severe general humoral reactions. Up to now the incompletely tested immunological phenomena are not specific for the polyalgia rheumatica and must be supplemented by further examinations.
Z Gesamte Inn Med 1980 Dec 15
PMID:[Observations on polymyalgia rheumatica]. 701 90

An acute loss of vision accompanied by signs of optic nerve head ischemia in an elderly patient should alert the examiner to suspect the presence of temporal arteritis until it can be proven otherwise. The patient presented here had ischemic optic neuropathy that was initially thought to be due to temporal arteritis, but eventually was proven to be associated with pronounced atherosclerotic aortic arch disease. The diagnosis was complicated by the severe loss of vision and by an elevated erythrocyte sedimentation rate (ESR). A temporal artery biopsy was normal, and other findings implicated the pronounced diffuse atherosclerosis as the cause of the ischemia of the optic nerve head. Therapy was directed toward the vascular occlusive disease, and involved an aortoinnominate bypass graft.
Am J Optom Physiol Opt 1981 Dec
PMID:Complicated aortic arch syndrome and ischemic optic neuropathy presenting as giant cell (temporal) arteritis. 703 43

A 58-year-old woman had a clinical history compatible with polymyalgia rheumatica but with an unexplained interstitial lung disease. Evaluation, including biopsy specimens of temporal artery, lung, and gastrocnemius muscle, was consistent with giant cell arteritis. This case identifies giant cell arteritis as a cause of interstitial lung disease.
Chest 1982 Dec
PMID:Giant cell arteritis presenting as interstitial lung disease. 714 Apr 7

Microangiopathic hemolytic anemia was found in a 67 year old woman with biopsy-proven giant cell arteritis. The patient's symptoms, as well as the hemolytic process, were suppressed by high-dose steroid therapy on several occasions. The presence of microangiopathic hemolytic anemia is consistent with the concept that erythrocyte fragmentation resulted from contract with intravascular fibrin. This is the first, reported case of microangiopathic hemolytic anemia with temporal arteritis.
Am J Med 1982 Dec
PMID:Giant cell arteritis and microangiopathic hemolytic anemia. 714 83


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