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Query: UMLS:C0039483 (giant cell arteritis)
 3,204 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Although cerebral angiography should be approached with caution in the diagnosis of inflammatory cerebro-vascular disease there are some characteristic angiographic findings which may be helpful for classification and differential diagnosis. The proximal cerebral arteries are favourably affected by basal meningitis and thrombangiitis obliterans with resulting stenoses and occlusions. Whereas those inflammations originating from neighbouring skull structures mostly involve the intracavernous parts of the carotid artery, the tuberculous and mycotic arteritis prefer the supraclinoid carotid siphon. Peripheral vascular changes are found in luetic endangiitis, necrotizing and toxic angiitis and in collagenoses. Simultaneous involvement of the temporal arteries is of great diagnostic importance demonstrating the systemic character of the inflammatory process; in Horton's arteritis it can be a pathognomonic finding. Infectious endocarditis, some mycoses and malaria may lead to embolic occlusion of cerebral vessels. Mycotic aneurysms mostly have a broad base or a fusiform shape and do not prefer the localizations of congenital aneurysms. Angiographically, abscesses, tuberculomas and viral encephalitis may result in circumscribed hypervascularized areas. The characteristic angiographic findings are exemplified and discussed on the basis of 8 cases of inflammatory cerebro-vascular disease (tuberculosis, pneumococcal and unspecific bacterial meningitis, syphilis, mycosis, Takayasu-syndrome, panarteritis nodosa, temporal arteritis).
Fortschr Neurol Psychiatr Grenzgeb 1975 Dec
PMID:[Inflammatory cerebro-vascular disease: angiographic findings and distribution patterns (author's transl)]. 0 27

Angiograms of 10 patients with giant cell arteritis who had large-artery and aortic abnormalities were reviewed. The affected arteries had multiple stenotic areas, and occlusions were relatively common, usually located at the end of tapered stenotic segments. Bridging collateral arteries usually refilled the distal portion of the occluded artery. The laterations were seen most frequently in the subclavian, axillary, and brachial arters, and the arteriographic lesions reflected the clinical findings. Such arteriographic abnormalities are suggestive of giant cell arteritis in a patient over the age of 50. The differential diagnosis includes Takayasu's disease, arteriosclerosis, thoracic outlet syndrome, and ergotism.
AJR Am J Roentgenol 1976 Dec
PMID:Extracranial angiographic findings in giant cell (temporal) arteritis. 1 99

Wegener's granulomatosis and forms of giant cell arteritis result from vasculitis and masquerade with symptoms of common head and neck disease entities. Recognition of the manifestations of vasculitis can be made early in the disease course and confirmed pathologically, allowing effective therapy. Current therapy of Wegener's granulomatosis with Cytoxin and Imuran and steroids for giant cell arteritis frequently results in reversal of head and neck involvement, prevention of systemic disease, and prolonged survival.
Laryngoscope 1978 Dec
PMID:The masquerade of vasculitis: head and neck diagnosis and management. 3 45

The authors report 40 cases of temporal arteritis, of which 16 were associated with pseudo-polyarthritis, and 8 cases of polyarthritis alone. The clinical picture of temporal arteritis in the elderly, includes headaches in 95% of cases, clinical changes in the superficial head arteries in 75% of cases, joint and muscle signs dominated by pseudo-polyarthritis in 40% of cases; general signs were practically constant. A major inflammatory syndrome was also constant. From the histological point of view, there was pan-arteritis with giant cells, and their wide diffusion is shown by the presence of eye signs in 27.5% of cases, brain signs in 10% of cases, and extra-cephalic vascular signs in 10%. The relationship in classification between temporal arteritis and polyarthritis of the roots of the limbs is recalled. The course is long, the duration of corticosteroid therapy should never be less than two years; relapses are common but the mortality appears low.
Sem Hop 1977 Dec 23
PMID:[Temporal arteritis and rhizomelic pseudo-polyarthritis. Clinical aspects and nosologic problems. Apropos of 48 cases]. 20 69

In cloning human fetal globin cDNA in bacterial plasmids, we obtained a recombinant which contained a fragment of gammg-globin cDNA corresponding to the region from amino acid 99 to the poly A. We determined a sequence of 169 nucleotides which included the complete 3' non-coding region of the gamma-globin mRNA. The codon for amino acid 136 was GCA, indicating that this cloned fragment was derived from the Agamma-globin gene. In conjunction with the surrounding sequences, the GCA codon provides the Agamma-species with a unique CTGCAG hexanucleotide that is recognized by the restriction enzyme Pst I. The 3'-untranslated region of the gamma-globin mRNA consists of 90 nucleotides, and shares little homology with that of the human beta-globin mRNA. As in other mammalian mRNAs, a symmetrical sequence and the hexanucleotide AAUAAA are present.
Nucleic Acids Res 1978 Dec
PMID:Sequence of the 3'-noncoding and adjacent coding regions of human gamma-globin mRNA. 31 63

The purpose of this paper, was to discuss central retinal artery occlusion and its role in the patient's overall health. Several different causes of occlusion such as cardiovascular diseases, carotid artery disease, aortic arch disease and giant cell arteritis are discussed along with their symptomatology and clinical manifestations. Because of the importance of a proper diagnosis, the more common ophthalmoscopic pictures that are confused with the central retinal artery occlusions are also included. A case report of a central retinal artery occlusion secondary to a carotid artery stenosis is presented to acquaint the optometrist to the need of further testing after a vascular accident to the eye.
J Am Optom Assoc 1979 Dec
PMID:Implications of central retinal artery occlusion. 52 84

Anterior segment ischemia is perhaps the most rare ocular manifestation of temporal arteritis. We described a 73-year-old woman with anterior segment ischemia in the course of temporal arteritis. Early recognition of the syndrome and treatment with high doses of steroids led to visual recovery in the involved eye.
South Med J 1977 Dec
PMID:Anterior segment ischemia in temporal arteritis. 59 6

With Doppler ultrasonography of the orbit the blood flow in the supratrochlear and supraorbital arteries can be determined transcutaneously. The technique yields reliable informations about the state of the carotid system. It is especially suitable for assessing carotid obstruction. Besides it has proved to be of particular diagnostic value in temporal arteritis. The authors describe and discuss the technique of orbital Doppler ultrasonography and present typical findings in carotid lesions and in temporal arteritis.
Klin Monbl Augenheilkd 1978 Dec
PMID:[Experiences with Doppler-ultrasonography of the orbital vessels for ophthalmological vascular diagnosis (author's transl)]. 73

Arterial emboli, fragmentation of both the arterial and venous blood columns, and bilateral cherry red spot were seen in the fundus of a patient with progressive onset of visual loss. Initially, the patient, a 56-year-old housewife, was thought to have temporal arteritis. Her clinical condition worsened on steroids which was subsequently discontinued when 5 out of 6 blood cultures were reported positive. Showers of microemboli were responsible for her unusual fundus findings.
Ann Ophthalmol 1978 Dec
PMID:Retinal embolization from endocarditis. 73 91

A laboratory evaluation was conducted of an impaction-beta detection recording respirable mass monitor (RRMM), a prototype of the commercial RDM-301 manufactured by GCA Corporation. Areas investigated were the effect of dust concentration, size distribution, and sampling time on the accuracy and precision of the RRMM instrument when compared with personal gravimetric samplers. Results showed a good linear correlation between 1 and 20 mg/m3. However, the RRMM underestimated the gravimetric concentration when a significant mass of submicrometer particles was present. A commercial RDM-301 was also tested, and a decrease in precision was observed with decreasing concentration for a set sample time.
Am Ind Hyg Assoc J 1978 Dec
PMID:Laboratory evaluation of a recording respirable mass monitor. 74 96


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