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Query: UMLS:C0039483 (
giant cell arteritis
)
3,204
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Interstitial lung disease (ILD) has rarely been reported as a manifestation of
giant cell arteritis
(
GCA
). We herein report a unique case of
GCA
in a 76-year-old woman who presented with ILD as an initial manifestation of
GCA
. Ten years before admission, she had been diagnosed with granulomatous ILD of unknown etiology. Corticosteroid therapy induced remission. One year after the cessation of corticosteroid therapy, she was admitted with a persistent fever. After admission, she developed left oculomotor paralysis. Positron emission tomography with 2-deoxy-2-[
fluorine
-18]fluoro-D-glucose integrated with computed tomography (
18
F-FDG PET/CT) proved extremely useful in establishing the diagnosis. Our case promotes awareness of
GCA
as a possible diagnosis for granulomatous ILD with unknown etiology.
...
PMID:Interstitial Lung Disease as an Initial Manifestation of Giant Cell Arteritis. 2888 53
Giant cell arteritis
(
GCA
) is the most common vasculitis in individuals older than 50 years in Western countries. In addition to the typical pattern of cranial ischemic manifestations, large vessel vasculitis (LVV) involvement has emerged as a common feature of
GCA
. Patients with predominant LVV manifestations differ from those with the cranial pattern. They are usually affected at a younger age and often have nonspecific manifestations such as constitutional syndrome, fever of unknown origin, or refractory/atypical polymyalgia rheumatica (PMR). In these patients, cranial manifestations are often absent. Furthermore, patients with isolated PMR should be followed up because of the potential risk of severe vascular complications in the setting of an underlying
GCA
. Whereas temporal artery biopsy and/or color duplex ultrasound of the temporal arteries is useful for the diagnosis of cranial
GCA
, Doppler sonography of the subclavian and axillary arteries,
fluorine
-18-fluorodeoxyglucose-positron emission tomography/computed tomography, magnetic resonance, and computed tomography-angiography are very useful to identify the presence of LVV, and they may play a potential role in the follow-up of these patients.
...
PMID:Early large vessel systemic vasculitis in adults. 3181 May 48
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