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Query: UMLS:C0039483 (giant cell arteritis)
 3,204 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

26 HLA antigens of the loci A and B were studied in 50 patients with pseudo-polyarthritis and in 300 control subjects without any joint disease. The arthritis was isolated and not associated with temporal arteritis. An increase in frequency of both HLA antigens was noted in the patients studied: HLA-B5 = 24% as against 13% in controls (P = 0.05 and Pc NS). HLA-Bw38 = 18% as against 5.33% in controls (p = 0.002 - Pc = o.05). The rise in frequency of HLA-B5 and HLA-Bw38 was also found in 19 subjects with polyarthritis and temporal arteritis but not in 31 patients with temporal arteritis alone. In this disease, a link with the HLA-B14 antigen was noted in 50 cases (22.9% as against 8.6% in control). These results suggest that arthritis and temporal arteritis although sometimes associated are probably distinct diseases.
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PMID:[HLA system and rhizomelic pseudopolyarthritis]. 19 97

The GCA RDM 101-1 has been evaluated using aerosols of coal, Arizona road dust, silica, potash, and rock (copper ore) particles. The effects of the dust mass concentration, particle size distribution, and dust material on the instrument response were investigated. The instrument was found to measure the mass concentrations of respirable dust aerosols up to about 16 mg/m3 for coal and rock dust and about 20 mg/m3 for silica, potash, and Arizona road dust, providing there is not appreciable mass in the size range below approximateley 0.7 micrometer aerodynamic diameter.
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PMID:An evaluation of the GCA respirable dust monitor 101-1. 20 80

The authors report 40 cases of temporal arteritis, of which 16 were associated with pseudo-polyarthritis, and 8 cases of polyarthritis alone. The clinical picture of temporal arteritis in the elderly, includes headaches in 95% of cases, clinical changes in the superficial head arteries in 75% of cases, joint and muscle signs dominated by pseudo-polyarthritis in 40% of cases; general signs were practically constant. A major inflammatory syndrome was also constant. From the histological point of view, there was pan-arteritis with giant cells, and their wide diffusion is shown by the presence of eye signs in 27.5% of cases, brain signs in 10% of cases, and extra-cephalic vascular signs in 10%. The relationship in classification between temporal arteritis and polyarthritis of the roots of the limbs is recalled. The course is long, the duration of corticosteroid therapy should never be less than two years; relapses are common but the mortality appears low.
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PMID:[Temporal arteritis and rhizomelic pseudo-polyarthritis. Clinical aspects and nosologic problems. Apropos of 48 cases]. 20 69

The authors report 7 cases of temporal arteritis, proved by biopsy, with unusual early symptoms. They emphasize dental extraction as a possible incitant of the disease. Diagnosis is very often overlooked when local symptoms of involvment of temporal arteries are lacking. Various head and neck pain, fever of unexplained origin, weight loss, when associated with erythrocyte sedimentation rate greater than 50 mm, should convince the physician to biopsy the temporal artery of people over the age of 60. Steroid therapy must begin as soon as diagnosis is made.
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PMID:[Early and unusual presentation of temporal arteritis. A report of 7 cases (author's transl)]. 21 91

The authors report a case of temporal arteritis accompanied with appearance of "cold areas" on the liver scan, regressing after steroid therapy. This observation confirms the existence of hepatic manifestation in giant cell arteritis and evokes a discussion of their mechanism. A hypothesis of hepatic ischemia is proposed.
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PMID:[A case of temporal arteritis accompanied with appearance of "cold areas" on the liver scan (author's transl)]. 22 79

Highly selective angiography was used to study eleven cases of Horton's arteritis. The results showed the presence of segmental vascular abnormalities which, though mainly affecting the temporal artery region, were also present in that of the internal maxillary artery. This examination procedure can be of great value by assisting the surgeon in his choice of biopsy sample, which is essential for diagnostic purposes.
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PMID:[External carotid arteriography in Horton's disease. A report on 11 observations (author's transl)]. 22 96

Determining the cause of systemic vasculitis can be facilitated by a clinicopathologic classification of the syndrome. The considerations in differential diagnosis include periarteritis nodosa, leukocytoclastic angiitis (hypersensitivity angiitis, Schonlein-Henoch purpura, other disease-associated vasculitis), Wegener's granulomatosis, allergic granulomatosis (granulomatous angiitis), and giant cell arteritis.
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PMID:The spectrum of systemic vasculitis: a classification to aid diagnosis. 24 Jan 57

Two young adults (aged 21 and 22 years) and two children (aged 7 and 8 years) complained of an unsightly, soft, painless unilateral nodule in the temporal region, ranging from 0.5 to 1.5 cm in diameter, clinically diagnosed as lipoma, sebaceous cyst, or dermoid cyst. In each instance, the patient had no evidence of systemic disease or history of trauma, and the nodule was excised for cosmetic reasons. Histologic examination of the lesions showed non-giant-cell granulomatous inflammation of the temporal arteries with intimal proliferation and microaneurysmal disruption of the media. Whether the lesions represent a juvenile form of temporal arteritis, an unusual form of localized polyarteritis nodosa, or Kimura disease (subcutaneous angiolymphoid hyperplasia with eosinophilia) remains conjectural.
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PMID:Juvenile temporal arteritis. Biopsy study of four cases. 24 Sep 51

This is a report of a 64 years old patient who experienced a transverse lesion of the spinal cord with quadriplegia caused by giant cell arteritis. It is stressed that giant cell arteritis not only affects the temporal arteries but on principle any other artery of the body. The giant cell arteritis generally is accompanied with similar humoral findigns as a malignant neoplasm. Therefor in a few cases with high spinal cord lesion suspected to be caused by a malignant tumour the giant cell arteritis may be the real cause, if a spinal mass is excluded. In order to prevent irreversible paralytic defects a cortisone therapy has to be started with as early as possible. It must be carried on for a long period to prevent a restarting of the inflammatory process.
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PMID:[Highly located transverse lesion of the cord with quadriplegia caused by giant cell arteritis (author's transl)]. 25 69

This article describes the infra-red fluorescent angiographic technique to study the choroidal circulation in normal and pathological conditions. The standard Zeiss fundus camera was modified to hold suitable excitation and barrier filters. The dye used was indocyanine green, which has been proved to be free from any untoward reaction and has less tendency to leak from the fenestrated choriocapillaris, unlike fluorescein. Results obtained in pathological conditions like temporal arteritis, choroidal naevus, malignant melanoma, and choroidal angiomas were better shown by this technique than by fluorescein angiography.
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PMID:Fluorescent infra-red angiography of the fundus oculi using indocyanine green dye. 28 95


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