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Query: UMLS:C0039483 (giant cell arteritis)
 3,204 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Elevated Factor VIII-von Willebrand factor antigen levels are associated with vascular endothelial injury in several disorders, including scleroderma, Raynaud's phenomenon, polymyalgia rheumatica, and temporal arteritis. Eight patients with serpiginous choroidopathy were evaluated with the use of quantitative immunoelectrophoresis for Factor VIII-von Willebrand factor antigen. The serpiginous choroidopathy patients had a mean Factor VIII-von Willebrand factor activity of 226 +/- 47.3%, whereas a disease-free, age- and sex-matched control group had a mean activity of 107 +/- 28%. These findings are statistically significant (P greater than 0.005) and suggest that in some patients, serpiginous choroidopathy represents an occlusive vascular phenomenon that involves the choroidal circulation.
Retina 1990
PMID:Serpiginous choroidopathy associated with elevated factor VIII-von Willebrand factor antigen. 240 59

A series of 24 consecutive patients presenting with a fundus picture characterized by a predominance of cotton-wool spots, or a single cotton-wool spot, is reported. Excluded were patients with known diabetes mellitus. Etiologic conditions found included previously undiagnosed diabetes mellitus in five patients, systemic hypertension in five patients, cardiac valvular disease in two patients, radiation retinopathy in two patients, and severe carotid artery obstruction in two patients. Dermatomyositis, systemic lupus erythematosus, polyarteritis nodosa, leukemia, AIDS, Purtscher's retinopathy, metastatic carcinoma, intravenous drug abuse, partial central retinal artery obstruction, and giant cell arteritis were each found in one patient. In only one patient did a systemic workup fail to reveal an underlying cause. The presence of even one cotton-wool spot in an otherwise normal fundus necessitates an investigation to ascertain systemic etiologic factors.
Retina
PMID:Cotton-wool spots. 386 24

Vision loss in giant cell arteritis (GCA) often presents as anterior ischemic optic neuropathy and central retinal artery occlusion. Previous studies have established an acute delay in choroidal perfusion on fluorescein angiography (FA) as a classic sign of GCA. The authors present a unique imaging case report of GCA where ultra wide-field (UWF) indocyanine green angiography (ICGA) offers improved characterization of delayed choroidal perfusion compared to FA. Routine use of ICGA, particularly UWF imaging, in patients with suspected GCA should be studied in a larger cohort to determine whether it may improve detection of choroidal perfusion delay. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:471-473.].
Ophthalmic Surg Lasers Imaging Retina 2016 05 01
PMID:Ultra Wide-Field Indocyanine Green Angiogram Highlights Choroidal Perfusion Delay Secondary to Giant Cell Arteritis. 2718 52

Giant cell arteritis (GCA) can present with cotton-wool spots in the retina and usually affects medium and large vessels. The authors present herein a 75-year-old man with GCA manifesting with cotton-wool spots and widespread retinal vasculitis affecting small-size retinal arterioles. The retinal vasculitis and the cotton-wool spots resolved after initiation of systemic corticosteroids and his vision returned to normal. GCA can uncommonly present with retinal vasculitis affecting small-size arterioles. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:1054-1056.].
Ophthalmic Surg Lasers Imaging Retina 2016 11 01
PMID:Small-Caliber Retinal Vasculitis Associated With Giant Cell Arteritis: A New Finding. 2784 1

An 85-year-old man presented with temporal headache and bilateral paracentral scotomas. Clinical examination, laboratory testing, and temporal artery biopsy confirmed the diagnosis of giant cell arteritis. Fluorescein angiography illustrated Amalric triangular choroidal infarction of the left eye. Spectral-domain optical coherence tomography of the left eye demonstrated outer nuclear layer abnormalities adjacent to the choroidal infarct. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:668-670.].
Ophthalmic Surg Lasers Imaging Retina 2017 08 01
PMID:Amalric Triangular Syndrome Associated With Outer Nuclear Layer Infarction. 2881 43

The authors present an unusual case of bilateral macular choroidal infarction as a manifestation of giant cell arteritis (GCA). Due to sequential bilateral presentation, multimodal imaging with spectral-domain optical coherence tomography allows for simultaneous evaluation of progressive stages of outer retinal damage caused by choroidal hypoperfusion seen on fluorescein and indocyanine green angiography. This case report demonstrates that GCA should be considered in the differential diagnosis of placoid maculopathies. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:540-543.].
Ophthalmic Surg Lasers Imaging Retina 2018 07 01
PMID:Bilateral Macular Choroidal Infarction as a Manifestation of Giant Cell Arteritis. 3002 Oct 43

A 73-year-old woman with 2 weeks of progressive painless vision loss was found to have bilateral corneal edema, jaw claudication, and temporal headache. Multimodal imaging revealed an Amalric choroidal infarct in the left eye visualized by widefield indocyanine green angiography and swept-source optical coherence tomography angiography (SS-OCTA). Prompt intravenous corticosteroid treatment resulted in 20/20 vision, and giant cell arteritis (GCA) was confirmed by a temporal artery biopsy. The case underscores the use of widefield SS-OCTA as a non-invasive test to aid in the diagnosis of GCA, as well as bilateral cornea edema as a rare presentation of GCA. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:e157-e160.].
Ophthalmic Surg Lasers Imaging Retina 2018 10 01
PMID:Swept-Source Optical Coherence Tomography Angiography of an Amalric Choroidal Infarction in a Rare Presentation of Giant Cell Arteritis With Bilateral Corneal Edema. 3039 79