Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038454 (stroke)
 147,016 document(s) hit in 31,850,051 MEDLINE articles (0.07 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 8976
MRI 3098
Mol 2442
tissue plasminogen activator 1705
insulin 1491
penumbra 1128
PLA 1085
renin 992
ATP 983
hemoglobin 975
cytokine 861
She 848
thrombin 831
fibrinogen 737
caspase-3 727
C-reactive protein 698
collagen 604
axonal 579
TNF 570
tumor necrosis factor 561
Pol 549
angiotensin II 546
calcium channel 544
albumin 498
HDL 497
brain-derived neurotrophic factor 478
vascular endothelial growth factor 471
CA1 454
IL-6 445
glial fibrillary acidic protein 427
myosin 412
superoxide dismutase 401
factor Xa 398
ADP 395
Bcl-2 387
prothrombin 385
CO2 382
nitric oxide synthase 358
ACE 346
thrombin inhibitor 334
amyloid precursor protein 328
matrix metalloproteinase 328
CSF 322
NMDA receptor 318
endothelin-1 316
inducible nitric oxide synthase 307
tPA 304
OGD 303
natriuretic peptide 278
ATPase 277
interleukin-6 274
MMP-9 272
lipopolysaccharide 270
glycoprotein 270
plasminogen 267
angiotensin receptor 261
ANOVA 259
CHA 249
von Willebrand factor 245
erythropoietin 242
phosphodiesterase 233
lactate dehydrogenase 233
gut 229
PI3K 229
endoplasmic reticulum 227
Ang II 226
protein C 225
MELAS 221
p38 218
urokinase-type plasminogen activator 216
IL-10 214
NMR 204
Mal 204
CBF 203
GABA 199
VEGF 199
vasopressin 198
MAPK 197
vascular endothelium 193
ERK1 189
thromboplastin 185
chemokine 184
ICD 184
SBP 182
catalase 182
endothelial nitric oxide synthase 181
plasminogen activator inhibitor-1 179
apolipoprotein E 178
CRP 177
heme oxygenase-1 177
chronic renal failure 175
TLR4 175
cyclooxygenase 174
ACS 173
p53 170
tRNA 167
serum albumin 167
CHD 167
protein S 166
collagenase 165
ASA 164
MAP 162
cytochrome c 162
HAS 161
occludin 161
GSH 160
DCX 160
reserved 159
ERK 159
glutamate receptor 159
ROS 157
Men 157
AKT 156
mTOR 155
myeloperoxidase 155
COX-2 155
ADL 155
reductase 155
angiotensin II receptor 154
methylenetetrahydrofolate reductase 152
creatine kinase 152
cyclooxygenase-2 152
B12 151
Gen 148
glucagon 148
bradykinin 145
Lp(a) 145
olfactory 142
factor V Leiden 138
DBP 134
glutathione peroxidase 133
P-selectin 132
SARS 131
p65 131
antithrombin III 130
AMP 129
JNK 127
asymmetrical 127
histone 126
Nrf2 124
neurotrophic factor 123
antithrombin 123
AT1 122
Rho 122
calpain 121
CD4 120
P2Y12 120
nerve growth factor 120
beta 1 120
estrogen receptor 120
adhesion molecule 119
MMP-2 119
LPS 119
erythroid 119
GPIIb 116
NAD 116
atrial natriuretic peptide 115
cytochrome P450 114
HMG-CoA reductase 112
TNF-alpha 111
more...
Disease
stroke 147016
hypertension 12305
myocardial infarction 9419
ischemia 8226
diabetes 7424
cerebral ischemia 5386
cardiovascular disease 4945
heart failure 4603
atherosclerosis 4424
transient ischemic attack 3311
depression 3192
Alzheimer's disease 3153
dementia 3074
cancer 3047
coronary artery disease 2879
coronary heart disease 2863
cerebral infarction 2478
heart disease 2167
obesity 2064
myocardial ischemia 2043
epilepsy 1864
congestive heart failure 1805
subarachnoid hemorrhage 1773
cognitive impairment 1758
hemiparesis 1737
Parkinson's disease 1716
plaque 1705
vascular disease 1666
acute myocardial infarction 1613
aphasia 1508
multiple sclerosis 1471
tumor 1313
migraine 1232
type 2 diabetes 1229
encephalopathy 1212
Ischemic stroke 1205
renal disease 1023
renal failure 929
neurological disease 826
lactic acidosis 788
pulmonary embolism 787
sickle cell disease 778
brain edema 765
hyperlipidemia 764
ventricular hypertrophy 745
dyslipidemia 739
coma 730
pneumonia 717
carotid artery stenosis 712
deep vein thrombosis 710
sepsis 701
dysphagia 693
hypercholesterolemia 679
metabolic syndrome 665
sepsis 656
hyperglycemia 645
essential hypertension 645
cardiomyopathy 612
chronic obstructive pulmonary disease 581
cold 573
peripheral vascular disease 570
amyotrophic lateral sclerosis 554
anemia 538
vasculitis 535
pulmonary hypertension 512
aortic stenosis 500
systemic lupus erythematosus 497
unstable angina 485
obstructive sleep apnea 459
moyamoya 435
osteoporosis 427
endocarditis 425
breast cancer 420
Huntington's disease 410
mitral regurgitation 394
Acute Stroke 392
cerebral palsy 383
infectious diseases 376
confusion 359
asthma 358
schizophrenia 358
HIV 356
mitochondrial myopathy 344
thrombocytopenia 344
Fibrillation 342
sleep apnea 339
hydrocephalus 334
arthritis 333
systolic hypertension 332
arteriopathy 331
blindness 331
chronic disease 327
proteinuria 327
SEM 326
status epilepticus 315
neuropathy 315
chronic renal failure 313
hyperhomocysteinemia 311
MELAS 311
meningitis 310
aortic regurgitation 307
antiphospholipid syndrome 307
retinopathy 304
carotid disease 299
lupus 296
encephalitis 295
fits 294
rheumatoid arthritis 293
dilated cardiomyopathy 289
cerebral embolism 289
arteriosclerosis 283
mitochondrial encephalomyopathy 283
hypoglycemia 281
idiopathic thrombocytopenic purpura 277
malnutrition 275
coagulopathy 268
brain atrophy 267
apraxia 266
Evans 260
preeclampsia 251
lung cancer 248
West 247
pituitary adenoma 242
dehydration 241
leukoencephalopathy 237
renal insufficiency 232
lupus 228
MELAS 227
valvular heart disease 226
psychosis 225
hypertrophic cardiomyopathy 224
major depressive disorder 223
pulmonary edema 211
incontinence 208
respiratory failure 207
mental illness 204
amaurosis 203
glucose intolerance 201
mitral stenosis 200
myopathy 199
cerebral vasospasm 199
CNS diseases 196
AIDS 195
delirium 193
brain tumor 191
cirrhosis 190
acute renal failure 187
dysplasia 186
DWI 186
ICD 184
parkinsonism 183
renal impairment 182
Thrombus 182
paraplegia 179
osteoarthritis 179
chronic pain 175
arteriovenous malformation 170
Fabry 170
aggression 168
atherosclerotic cardiovascular disease 167
more...
Symptom
seizures 2225
headache 1948
functional recovery 1910
pain 1757
anesthesia 1621
weakness 1048
angina 1029
hemiplegia 1017
spasticity 807
hypothermia 740
fatigue 641
overweight 421
paresis 415
ataxia 412
dysarthria 398
dizziness 358
syncope 345
vomiting 343
vertigo 312
dyspnea 294
regurgitation 288
collapse 267
chest pain 264
exhaustion 263
tremor 239
nausea 238
hypercapnia 220
sleepiness 200
cough 176
ophthalmoplegia 175
dystonia 172
spasm 169
respiratory distress 145
discomfort 143
numbness 141
discomfort 136
insomnia 123
analgesia 119
shoulder pain 119
diarrhea 118
hyperoxia 115
apathy 112
neurological disability 110
neck pain 109
abdominal pain 103
hypertonia 99
snoring 96
myoclonus 96
memory loss 94
tinnitus 91
agitation 89
back pain 84
cerebellar ataxia 79
chorea 78
paresthesia 77
thinning 76
lethargy 74
hypocapnia 71
consciousness disturbance 68
livedo 64
constipation 63
shortness of breath 61
low back pain 58
blurred vision 54
menopausal symptoms 54
presyncope 53
flushing 52
abnormal gait 49
nausea and vomiting 47
anorexia 45
Depressive symptoms 43
Ill 43
hypotonia 42
facial droop 40
hemoptysis 39
paraparesis 39
muscle stiffness 36
myalgia 36
starvation 35
cyanosis 34
exertional dyspnea 34
arthralgia 33
asthenia 33
CSR 33
acute pain 32
arm weakness 31
dysesthesia 31
anosmia 31
facial pain 30
splenomegaly 30
tingling 29
breath holding 29
incoordination 29
acute stress 28
bradykinesia 28
tonic-clonic seizure 28
tachypnea 26
asynergy 25
partial seizure 25
stigma 24
Central post-stroke pain 23
exertional angina 23
lightheadedness 22
clonus 21
pallor 21
hypersomnia 21
Stiffness 21
erythema 20
hot flushes 20
photophobia 20
Aphasic 20
neuralgia 20
Spastic 20
joint stiffness 20
hoarseness 19
limb pain 19
Neuropathic pain 19
Neurologic symptoms 19
cachexia 18
despair 18
leg pain 18
Amaurosis fugax 18
distraction 17
loss of balance 17
oliguria 17
polyuria 17
meningism 17
hot flashes 16
hepatomegaly 16
asterixis 16
tense 16
neck stiffness 16
catatonia 15
muscle cramps 15
intestinal bleeding 15
sinus pressure 15
athetosis 14
blepharospasm 14
muscle rigidity 14
rhinorrhea 14
clumsiness 14
eds 14
loss of taste 14
chills 13
epigastric pain 13
ataxic gait 13
acidity 13
fever of unknown origin 12
Visuospatial neglect 12
orthopnea 12
drooling 12
clubbing 11
Todd's paralysis 11
Hemiballism 11
rigors 11
torticollis 11
mental fatigue 11
Sedation 11
polydipsia 11
knee pain 11
more...
Drug
Cardiovasc 3244
CVA 472
CSF 331
Monit 320
Clopidogrel 245
MAP 228
nitroglycerin 221
ROS 157
Vitamin K 157
Posture 145
vitamin E 142
Spectrum 140
Apixaban 119
caffeine 118
TTC 118
ROC 117
ascorbate 109
lysine 107
Alteplase 104
Angiotensin II 103
Nephron 97
Dial 95
Alteplase 89
Dermatol 87
Alteplase 86
NADH 68
CTA 66
Captopril 63
niacin 56
TAT 53
Cilostazol 51
Perindopril 50
TMS 50
Leaf 49
Simvastatin 48
Ximelagatran 48
Frontal 47
Ramipril 44
ABC 43
ETA 39
Estrogens 39
Ethanol 39
Portal 39
Heme 38
Streptokinase 38
Glucagon 38
EPI 35
Nitric Oxide 35
EE2 34
MRC 33
Ringer's solution 33
Albumin 33
Pravastatin 33
Propofol 32
AMC 32
Valsartan 32
Indomethacin 32
G-CSF 32
ICI 31
Coumadin 31
Atenolol 28
Amrinone 28
EPA 28
IL-2 28
ampicillin 27
Atropine 27
CaCl2 26
p75 26
Nephron 26
THF 26
Vitamin E 26
CPR 26
Abciximab 25
Spectrum 25
Rosuvastatin 25
Tenecteplase 25
Glutathione 25
Clonidine 24
Alliance 24
uPA 24
Fraction 24
Argatroban 24
IFN-gamma 24
Ezetimibe 23
ACT 23
Rosiglitazone 23
Isradipine 23
Diamox 22
CaCl2 22
CaCl2 22
Liraglutide 22
Asthma 22
ENT 21
Levosimendan 21
Serum albumin 21
Plavix 21
Histamine 20
MgSO4 20
Sodium nitroprusside 20
Enoximone 20
Felodipine 20
Fentanyl 19
IL-1ra 19
Vitamin B12 18
TAK 18
PFA 18
Raloxifene 18
PCP 18
Urokinase 17
Phentolamine 17
Ibopamine 17
Bayer 17
Vinpocetine 17
Ginseng 16
Gel 16
Norplant 15
ADM 15
Trandolapril 15
Dopexamine 15
PTH 15
Fluorescein 15
PPA 14
CTX 14
Bevacizumab 14
Ouabain 14
Dakar 14
Check 13
Donepezil 13
citric acid 13
Piracetam 13
Aggrenox 13
Growth hormone 13
Ancrod 12
Growth hormone 12
Dronedarone 12
Adenosine triphosphate 12
Diphenhydramine 12
Lubeluzole 12
Glycerol 12
Phenytoin 11
Android 11
Triad 11
Molsidomine 11
Lacidipine 11
LMWH 11
Nebivolol 11
Fondaparinux 10
Lovastatin 10
pyridoxal phosphate 10
Olmesartan 10
CoCl2 10
Parkin 10
CoCl2 10
Parkin 10
Triclosan 10
Aliskiren 10
Methylene blue 10
Bivalirudin 10
DPA 10
Asn 10
more...
Enzyme
tissue plasminogen activator 2228
renin 992
thrombin 810
mitogen-activated protein kinase 618
caspase-3 594
thromboplastin 590
ACE 581
superoxide dismutase 479
protein kinase 360
ERK 333
APC 312
ATPase 295
lactate dehydrogenase 248
catalase 233
phosphodiesterase 233
creatine kinase 214
urokinase-type plasminogen activator 212
peroxidase 208
NO synthase 207
collagenase 207
NADPH oxidase 200
protein kinase C 182
luciferase 178
NADPH oxidase 176
ACS 173
methylenetetrahydrofolate reductase 163
MAP 163
methylenetetrahydrofolate reductase 163
plasmin 162
focal adhesion kinase 161
PARP 141
glutathione peroxidase 136
AMP-activated protein kinase 121
complex I 108
NOS 106
phospholipase A2 100
GSK 94
acetylcholinesterase 93
CAD 90
CAD 90
CAD 90
alanine aminotransferase 87
proteasome 84
caspase-1 80
heme oxygenase 75
aspartate aminotransferase 69
AMPK 68
MEK 65
P-glycoprotein 64
matrix metalloproteinase 9 64
AMPK 63
guanylate cyclase 62
alkaline phosphatase 61
succinate dehydrogenase 60
kallikrein 59
cytochrome oxidase 58
phosphatidylinositol 3-kinase 55
calcineurin 55
phosphoinositide 3-kinase 54
TAT 53
monoamine oxidase 52
xanthine oxidase 51
tyrosine hydroxylase 48
cholinesterase 47
botulinum neurotoxin 45
reverse transcriptase 45
alpha-galactosidase 44
kinesin 43
adenylate cyclase 42
CD10 40
trypsin 38
3-hydroxy-3-methylglutaryl coenzyme A reductase 38
MMP 38
FAST 37
lipoxygenase 36
soluble epoxide hydrolase 36
caspase-9 36
prolyl hydroxylase 34
phospholipase C 34
matrix metalloproteinase 2 34
glutathione reductase 33
CPR 33
caspase-8 33
MIP 30
MMP-3 30
arginase 29
choline acetyltransferase 28
enolase 28
pyruvate dehydrogenase 27
CYP3A4 27
15-lipoxygenase 27
RNase 26
elastase 26
glutathione S-transferase 26
RNase 25
NQO1 25
cystathionine beta-synthase 24
paraoxonase 24
PTA 24
ancrod 24
cathepsin B 23
aldehyde dehydrogenase 23
PDE 23
peroxiredoxin 23
CaMKII 23
RNA polymerase 23
lipase 23
lipoprotein lipase 23
glucose-6-phosphate dehydrogenase 22
pyruvate dehydrogenase 22
pyruvate dehydrogenase 22
paraoxonase 22
ceruloplasmin 22
citrate synthase 22
angiotensin-converting enzyme 2 22
PKG 21
furin 21
ATP synthase 21
gamma-glutamyl transpeptidase 20
alcohol dehydrogenase 20
PDK1 19
glyceraldehyde-3-phosphate dehydrogenase 19
IKK 19
PCP 19
PRA 19
beta-lactamase 19
glutamine synthetase 19
tissue kallikrein 18
CPT 18
hyaluronidase 17
TdT 17
myosin ATPase 17
proprotein convertase 17
endonuclease 17
ornithine decarboxylase 16
CCS 16
diamine oxidase 16
cholesterol acyltransferase 16
protein phosphatase 2A 16
subtilisin 16
adenosine deaminase 15
Thy1 15
ADH 15
cdc2 14
AST 14
AOR 14
apyrase 14
TMT 14
neutrophil elastase 14
adenosine deaminase 14
glyceraldehyde-3-phosphate dehydrogenase 14
MCS 13
endothelin-converting enzyme 13
diaphorase 13
phosphofructokinase 13
carbonic anhydrase 13
DNA polymerase 12
glyceraldehyde-3-phosphate dehydrogenase 12
aldehyde dehydrogenase 12
chymase 12
more...
Compound
Dec 9681
Clin 7683
oxygen 6437
Cardiol 4649
glucose 3524
water 2488
calcium 2484
sodium 1583
DNA 1517
Cereb 1380
glutamate 1341
nitric oxide 1258
ATP 986
salt 775
CO2 773
ASA 772
creatinine 731
potassium 729
homocysteine 661
acetate 591
TNF 570
ADP 545
iron 539
arginine 482
aldosterone 465
His 455
phosphate 453
ADP 397
ADP 396
Warfarin 383
hydrogen 383
ethanol 381
NMDA 344
nitrogen 336
MCA 325
MCA 324
noradrenaline 322
Neuronal 263
prostacyclin 224
Angiotensin II 218
cysteine 214
Optimal 211
leucine 211
sulfate 207
urea 207
GABA 202
GABA 199
vitamin D 192
zinc 188
serine 181
Glutamate 181
MAP 180
GSH 177
GSH 177
ACS 174
ACS 173
cAMP 171
tyrosine 170
Insulin 162
methionine 157
Vitamin K 157
galactose 154
lysine 154
Cholesterol 153
Estrogen 153
iodine 151
DSM 149
nitrate 148
AMP 145
TTC 142
NAD 141
dUTP 138
Estrogen 137
cGMP 135
DBP 135
DBP 134
nicotinamide 133
MTT 130
AMPA 124
Heparin 119
caffeine 119
Salt 117
NAD 116
Thrombin 116
Pac 111
5-HT 111
PEG 110
alanine 105
Mg2+ 103
PMA 103
Ang II 102
Homocysteine 101
Homocysteine 101
Dobutamine 100
fluorine 99
tryptophan 99
H2O2 97
Dial 96
PCI 96
Statin 95
glycerol 95
Losartan 94
copper 94
phosphocreatine 92
AHA 91
Sodium 91
bromide 88
ACTH 87
NADPH 87
NADPH 87
ADP-ribose 85
Melatonin 85
PEP 85
tryptophan 84
SEE 82
Adrenal 81
threonine 81
tryptophan 80
tryptophan 80
Edaravone 79
Adenosine 79
N2O 78
Fibrinogen 78
Dopamine 75
S-adenosylhomocysteine 75
gamma-aminobutyric acid 75
Nifedipine 74
Cocaine 74
phosphorus 73
Ticlopidine 73
Hearts 72
Lactate 72
6-12 72
Isoproterenol 72
DDD 72
Phe 72
Off 72
Asp 71
Retinal 70
TEM 70
selenium 70
Norepinephrine 70
Hemoglobin 70
Propranolol 69
NADH 68
Progesterone 68
PGE2 67
silver 67
coenzyme Q10 67
mercury 67
Verapamil 67
manganese 66
Evans Blue 65
PEG 65
Propranolol 65
N-acetylaspartate 65
Hearts 64
Nimodipine 64
SAH 63
sodium chloride 62
more...