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Query: UMLS:C0038454 (stroke)
 147,016 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Dilatol (Nylidrin), a betamimetic used for tocolysis, was applied to ten hypertensive women in advanced pregnancy and produced in them characteristic effects with favourable impact upon oxygen supply to the foetuses, such as significant lowering of diastolic pressure, decrease in total peripheral resistance which reflected increase in uteroplacental blood flow, as well as rises in heart rate, stroke volume, and cardiac output. Nylidrin, therefore, may be recommended as a hypotensive drug in the treatment of arterial hypertension in pregnancy.
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PMID:[Dilatol for hypertension therapy in pregnancy (author's transl)]. 53 32

8 normotensive late pregnant women were examined before, during and after the intravenous administration of nylidrin (Dilatol) with the method of quantitative sphygmometry, the bloodless graphic registration of the arterial blood pressure and the direct electronic timing of pulse wave velocity. Systolic blood pressure remains unchanged; mean and diastolic blood pressure and total peripheral resistance decrease. Simultaneously heart rate, stroke volume and above all cardiac output increase. The hemodynamic mode of action of nylidrin is a favourable one in regard to the perfusion of tissues in pregnancy, because the fall of total peripheral resistance is much more pronunciated than the decrease of blood pressure. Therefore there are no objections to a tocolytic treatment with nylidrin in normotensive pregnant women on the part of cardiovascular system.
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PMID:[Cardiovascular effects of nylidrin (Dilatol) in pregnancy]. 98 83