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Query: UMLS:C0038454 (stroke)
 147,016 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Atrial Fibrillation (AF), either permanent or intermittent (paroxysnal AF), increases the risk of cardioembolic stroke. Accurate diagnosis of AF is obligatory for initiation of effective treatment to prevent stroke. Long term cardiac monitoring improves the likelihood of diagnosing paroxysmal AF. We used a deep learning system to detect AF beats in Heart Rate (HR) signals. The data was partitioned with a sliding window of 100 beats. The resulting signal blocks were directly fed into a deep Recurrent Neural Network (RNN) with Long Short-Term Memory (LSTM). The system was validated and tested with data from the MIT-BIH Atrial Fibrillation Database. It achieved 98.51% accuracy with 10-fold cross-validation (20 subjects) and 99.77% with blindfold validation (3 subjects). The proposed system structure is straight forward, because there is no need for information reduction through feature extraction. All the complexity resides in the deep learning system, which gets the entire information from a signal block. This setup leads to the robust performance for unknown data, as measured with the blind fold validation. The proposed Computer-Aided Diagnosis (CAD) system can be used for long-term monitoring of the human heart. To the best of our knowledge, the proposed system is the first to incorporate deep learning for AF beat detection.
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PMID:Automated detection of atrial fibrillation using long short-term memory network with RR interval signals. 3003 35

The interpretation of various cardiovascular blood flow abnormalities can be identified using Electrocardiogram (ECG). The predominant anomaly due to the blood flow dynamics leads to the occurrence of cardiac arrhythmias in the cardiac system. In this work, estimation of cardiac output (CO) parameter using blood flow rate analysis is carried out, which is a vital parameter to identify the subjects with left- ventricular arrhythmias (LVA). In particular, LVA is a resultant component of characteristic changes in blood rheology (blood flow rate). The CO is an intrinsic parameter derived from the stroke volume (SV) characterized by end-diastolic/systolic volumes (EDV/ESV) and heart rate. The pumping of blood from left ventricle (LV) reconciles in to R-R intervals depicted on ECG, which are used for heart rate estimation. The deviation from the nominal values of CO implies that, the subject is more prone to LVA. Further, the identification of subjects with LVA is accomplished by computing the features from the ECG signals. The proposed Feature Ranking Score (FRS) algorithm employs different statistical parameters to label the score of the extracted features. The feature score enables the selection optimal features for classification. The optimal features are further given to the Least Square- Support Vector Machine (LS-SVM) classifier for training and testing phases. The signals are acquired from public domain MIT-BIH arrhythmia database, used for validating the proposed technique for identifying the LVA using blood flow.
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PMID:An Efficient Cardiac Arrhythmia Onset Detection Technique Using a Novel Feature Rank Score Algorithm. 3105 39

Atrial fibrillation (AF) is a serious heart arrhythmia leading to a significant increase of the risk for occurrence of ischemic stroke. Clinically, the AF episode is recognized in an electrocardiogram. However, detection of asymptomatic AF, which requires a long-term monitoring, is more efficient when based on irregularity of beat-to-beat intervals estimated by the heart rate (HR) features. Automated classification of heartbeats into AF and non-AF by means of the Lagrangian Support Vector Machine has been proposed. The classifier input vector consisted of sixteen features, including four coefficients very sensitive to beat-to-beat heart changes, taken from the fetal heart rate analysis in perinatal medicine. Effectiveness of the proposed classifier has been verified on the MIT-BIH Atrial Fibrillation Database. Designing of the LSVM classifier using very large number of feature vectors requires extreme computational efforts. Therefore, an original approach has been proposed to determine a training set of the smallest possible size that still would guarantee a high quality of AF detection. It enables to obtain satisfactory results using only 1.39% of all heartbeats as the training data. Post-processing stage based on aggregation of classified heartbeats into AF episodes has been applied to provide more reliable information on patient risk. Results obtained during the testing phase showed the sensitivity of 98.94%, positive predictive value of 98.39%, and classification accuracy of 98.86%.
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PMID:Detection of Atrial Fibrillation Episodes in Long-Term Heart Rhythm Signals Using a Support Vector Machine. 3201 20

Neurofeedback-guided motor-imagery training (NF-MIT) has been proposed as a promising intervention following upper limb motor impairment. In this intervention, paretic stroke patients receive online feedback about their brain activity while conducting a motor-imagery (MI) task with the paretic limb. Typically, the feedback provided in NF-MIT protocols is an abstract visual signal based on a fixed trial. Here we developed a self-paced NF-MIT paradigm with an embodiable feedback signal (EFS), which was designed to resemble the content of the mental act as closely as possible. To this end, the feedback was delivered via an embodiable, anthropomorphic robotic hand (RH), which was integrated into a closed-looped EEG-based brain-computer interface (BCI). Whenever the BCI identified a new instance of a hand-flexion or hand-extension imagination by the participant, the RH carried out the corresponding movement with minimum delay. Nine stroke patients and nine healthy participants were instructed to control RH movements as accurately as possible, using mental activity alone. We evaluated the general feasibility of our paradigm on electrophysiological, subjective and performance levels. Regarding electrophysiological measures, individuals showed the predicted event-related desynchronization (ERD) patterns over sensorimotor brain areas. On the subjective level, we found that most individuals integrated the RH into their body scheme. With respect to RH control, none of our participants achieved a high level of control, but most managed to control the RH actions to some degree. Importantly, patients and controls achieved similar performance levels. The results support the view that self-paced embodiable NF-MIT is feasible for stroke patients and can complement classical NF-MIT.
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PMID:Exploring Self-Paced Embodiable Neurofeedback for Post-stroke Motor Rehabilitation. 3203 98

Atrial fibrillation is the most common arrhythmia and is associated with high morbidity and mortality from stroke, heart failure, myocardial infarction, and cerebral thrombosis. Effective and rapid detection of atrial fibrillation is critical to reducing morbidity and mortality in patients. Screening atrial fibrillation quickly and efficiently remains a challenging task. In this paper, we propose SS-SWT and SI-CNN: an atrial fibrillation detection framework for the time-frequency ECG signal. First, specific-scale stationary wavelet transform (SS-SWT) is used to decompose a 5-s ECG signal into 8 scales. We select specific scales of coefficients as valid time-frequency features and abandon the other coefficients. The selected coefficients are fed to the scale-independent convolutional neural network (SI-CNN) as a two-dimensional (2D) matrix. In SI-CNN, a convolution kernel specifically for the time-frequency characteristics of ECG signals is designed. During the convolution process, the independence between each scale of coefficient is preserved, and the time domain and the frequency domain characteristics of the ECG signal are effectively extracted, and finally the atrial fibrillation signal is quickly and accurately identified. In this study, experiments are performed using the MIT-BIH AFDB data in 5-s data segments. We achieve 99.03% sensitivity, 99.35% specificity, and 99.23% overall accuracy. The SS-SWT and SI-CNN we propose simplify the feature extraction step, effectively extracts the features of ECG, and reduces the feature redundancy that may be caused by wavelet transform. The results shows that the method can effectively detect atrial fibrillation signals and has potential in clinical application.
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PMID:SS-SWT and SI-CNN: An Atrial Fibrillation Detection Framework for Time-Frequency ECG Signal. 3250 59


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