Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038454 (
stroke
)
147,016
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Lorcainide hydrochloride
given at the doses of 150 mg i.v. proved to be well tolerated at the acute stage of a myocardial infarction; the subjective signs were benign and never prevented us from completing the injection. The haemodynamic changes reflect some depressive effects on the myocardial function. Most of the observed changes are transient, and when significant from the statistical point of view, they remain very mild: the cardiac output decreased from 3.4 to 3.2 l/min per m2, the
stroke
index from 46 to 41 ml/m2, the pulmonary wedge pressure increases from 6.6 to 8.4 mm Hg (mean values).
Lorcainide hydrochloride
may thus be used as an antiarrhythmic drug in acute myocardial infarction.
...
PMID:Haemodynamic reactions after intravenous injection of lorcainide hydrochloride in acute myocardial infarction. 725 Jan 67