Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038454 (stroke)
 147,016 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors analysed the effectiveness of Lipanthyl treatment in 38 patients after stroke undergoing rehabilitation treatment. The effects of the drug were evaluated on the general condition, neurological and psychic status, progression of motor rehabilitation, and on lipid metabolism parameters. A statistically significant improvement was obtained in the subjective and psychic condition, and the results of motor rehabilitation were slightly better than in the compared groups of patients. Lipid metabolism was normalized only in part (cholesterol, chylomicrons). In the conclusions the authors state that it is useful to give this drug to patients with cerebral atherosclerosis only if disturbances of lipid metabolism coexist with this disease and are refractory to dietetic treatment.
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PMID:[Changes in blood lipids after stroke in patients treated with lipanthyl]. 687

Atherosclerosis is the major cause of heart attack and stroke in the western world. In this paper we present a computerized method for segmenting the athrerosclerotic carotid plaque from ultrasound images. The method uses the blood flow image first to detect the initial contour of the plaque, and then despeckle filtering and snakes to deform the initial contour for best fit of plaque boundaries. The accuracy and reproducibility of this method was tested using 35 longitudinal ultrasound images of carotid arteries and the results were compared with the manual delineations of an expert. The comparison showed that the computerized method gives satisfactory results with no manual correction needed in most of the cases. The true positive fraction, TPF, true negative fraction, TNF, false negative fraction, FNF and false positive fraction, FPF, were 86.44%, 84.03%, 8.5%, and 7% respectively.
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PMID:Atherosclerotic carotid plaque segmentation. 1727 56