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Query: UMLS:C0038454 (stroke)
 147,016 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Effects of font design and electronic display parameters upon text legibility were determined using a threshold size method. Participants' visual acuity (inverse of the minimum detection size, representing the threshold legibility for each condition) was measured using upper- and lowercase letters and lowercase words in combinations of 6 fonts, 3 font-smoothing modes, 4 font sizes, 10 pixel heights, and 4 stroke widths. Individual lowercase letters were 10% to 20% more legible than lowercase words (i.e., lowercase words must be 10%-20% larger to have the same threshold legibility). This letter superiority effect suggests that individual letters play a large role and word shape plays a smaller role, if any, in word identification at threshold. Pixel height, font, stroke width, and font smoothing had significant main effects on threshold legibility. Optimal legibility was attained at 9 pixels (10 points). Verdana and Arial were the most legible fonts; Times New Roman and Franklin were least legible. Subpixel rendering (ClearType) improved threshold legibility for some fonts and, in combination with Verdana, was the most legible condition. Increased stroke width (bold) improved threshold legibility but only at the thinnest width tested. Potential applications of this research include optimization of font design for legibility and readability.
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PMID:Text legibility and the letter superiority effect. 1655 67

Arial fibrillation (AF) is the most commonly occurring sustained arrhythmia in the United States and is associated with increased mortality. AF is a risk factor for ischemic stroke, and risk factors for AF include comorbid conditions such as congestive heart failure, diabetes mellitus, older age, hypertension, diabetes, pulmonary disease, and history of stroke, transient ischemic attack, or heart failure. Risk stratification for ischemic stroke in AF patients is based on scoring a group of risk factors that allows for the appropriate tailoring of antithrombotic therapy. The vitamin K antagonists are effective at reducing ischemic stroke rates in medium-risk to high-risk patients and are therefore generally recommended for this group. However, a large proportion of these patients are not treated with vitamin K antagonists because of the potential for adverse outcomes, particularly in elderly patients. New direct thrombin inhibitors and direct Factor Xa inhibitors in development offer the possibility of simplifying treatment and management although offering similar or better efficacy and safety profiles to warfarin. In light of these potential new treatments, the importance and improvement of risk stratification methods and the resulting recommendations in thromboprophylaxis become even more paramount as they make it more likely that medium-risk to high-risk patients can be treated safely.
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PMID:The impact of comorbidities on stroke prophylaxis strategies in atrial fibrillation patients. 2207 96

Arial myxoma can present as stroke and should be considered as a differential diagnosis of stroke in young individuals. We present here a 42 years female who presented with sudden loss of conciousness. After extensive work up for young stroke, left atrial myxoma was detected and tumor was removed surgically and histopathological report was consistent with the atrial myxoma.
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PMID:Atrial myxoma: a rare cause of ischemic stroke. 2448 70