Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038454 (
stroke
)
147,016
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We studied whether cardiac abnormalities contribute to the increased risk of
stroke
in patients with nonvalvular atrial fibrillation (NVAF). M-mode and 2D echocardiography were performed in four age- and gender-matched groups: 20
stroke
patients with NVAF, 20 patients with NVAF who had not suffered a previous
stroke
, 20
stroke
patients with sinus rhythm, and 40 healthy controls. Their mean age was 77 years. The two groups with atrial fibrillation differed from healthy controls in that they had more 2D-echocardiographic findings of severe left-ventricular-wall-motion abnormalities (p < 0.05) and tended more often to have enlarged left ventricles, and hypertrophic and congestive cardiomyopathy. Left atrial diameter was 47 mm compared to 41 and 39 mm in the two groups with sinus rhythm (p < 0.001). Intracardiac thrombi were only found in the two atrial-fibrillation groups (with
stroke
: 15% without
stroke
: 5%).
Aortic sclerosis
was common in all groups (30-60%), as was mitral annulus calcification (10-20%). The only significant difference between the two atrial-fibrillation groups was a higher frequency of earlier ischemic heart disease in the
stroke
group. Both atrial-fibrillation groups had cardiac abnormalities predisposing for embolic as well as thrombotic
stroke
.
...
PMID:Echocardiographic findings and the increased risk of stroke in nonvalvular atrial fibrillation. 130 Dec 43
Echocardiography assumes a major role in the diagnosis and evaluation of cardiovascular disease in the older population. Available diagnostic modalities are briefly reviewed and their role in identifying disease entities common in a geriatric population is discussed. The prognostic implications of echocardiographic findings of mitral annular calcification and
aortic sclerosis
are reviewed, as are the use of echo and Doppler techniques in the assessment of congestive heart failure. Particular emphasis is placed on the evaluation of ischemic heart disease using stress echocardiography, the diagnosis and assessment of degenerative aortic valve disease, and the role of transesophageal echo in the management of atrial fibrillation and
stroke
.
...
PMID:Echocardiography. The role of this noninvasive test in the geriatric population. 1287 62