Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038454 (
stroke
)
147,016
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Although chorion
carcinoma of the uterus
is the seventh commonest in the comparative frequency of malignant tumours seen at the Cancer Registry of the University College Hospital, Ibadan, Nigeria (being exceeded in order of commoness by the reticuloendothelial tumours, carcinoma of the cervix, liver, breast, stomach and ovary), it is the most frequent source of tumour deposit of the brain in this hospital. Between 1960 and 1969, 197 Nigerians with chorion cancer of the uterus were admitted to UCH; in twenty-five of them the nervous system was involved during the course of their disease. The neurological involvement presented as acute
cerebrovascular accident
in fourteen, encephalitis in five; as primary intracranial space-occupying lesion in three cases and in one patient, as cord compression. There were no obvious neurological features in two cases in which necropsy revealed brain metastases. Involvement of the nervous system carries a poor prognosis in chorion cancer of the uterus.
...
PMID:The neurology of metastatic chorion carcinoma. 82 2
Not infrequently, great difficulty is encountered in the operation for advanced cervical
carcinoma of the uterus
in dissecting cancerous tissues and controlling incidental bleeding. The CUSA is a major achievement of modern ultrasonic technology, and has been used by us to overcome such difficulties in 6 cases of total pelvic exenteration, 4 of anterior pelvic exenteration, 1 of posterior pelvic exenteration, 2 of cardinal ligament extirpation and 21 of radical hysterectomy. The handpiece of the CUSA contains a hollow titanium tip which vibrates longitudinally along its axis, driven by a magnetostrictive transducer. The vibration occurs with a frequency of 23 kHz and with an adjustable
stroke
of 0-300 microns. The tip of the device, placed in contact with the target tissues, destroys and emulsifies the cell membranes, which are irrigated and removed through a built-in suction tube. Since vessels larger than 0.5mm in diameter, nerves and fibrous tissue capsules contain much collagen, they rebound with the ultrasonic vibration waves emitted by the CUSA, and consequently they are left unimpaired by the procedure. It was noted in our operations that the larger the degree of tip excursion of the CUSA, the greater was the power added to fragment the target tissues. The effectiveness also depended upon the amount of water contained in the tissues. A very accurate sensation of the consistency of tissues was obtainable through the tip of the device in contact with them. This tactile feedback was quite helpful in enabling us to differentiate between target tissues. A clear visualization of detailed structures of vasculature and nerves in the pelvic cavity was attained as a result of sweeping dissection using the CUSA, and thereby extensive elimination of the cancerous tissues and lymph nodes was facilitated.
...
PMID:[Usage of the CUSA (cavitron ultrasonic surgical aspirator) in radical surgery of cervical carcinoma of the uterus]. 359 94