Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038454 (stroke)
 147,016 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We conducted a retrospective study of 29 diabetic patients (16 women and 13 men, all at least 60 years old) who underwent intraocular lens implantation (23 anterior chamber lenses, three iris-supported lenses, and three posterior chamber lenses) in conjunction with cataract extraction. The cataracts were either unilateral or, if bilateral, there was a four-line difference in visual acuity between fellow eyes. We included only patients with no diabetic retinopathy or only minimal background angiopathy. There were no surgical complications in any of the eyes. Transient postoperative increases in intraocular pressure were easily controlled with medication. Final corrected visual acuities ranged from 20/20 to 20/200; 20 of the 29 patients achieved final visual acuities of 20/40 or better. In two patients, background retinopathy became active, leading to significant macular edema four months and one year later. In both cases, the macular edema decreased visual acuity from 20/30 to 20/200, although the visual acuity in one eye returned to 20/40 after laser photocoagulation. One patient had a cerebral vascular accident resulting in cortical blindness five months postoperatively and another developed rubeosis iridis and neovascular glaucoma 15 months postoperatively.
 ...
PMID:Experience with intraocular lens implants in patients with diabetes. 686 84

A 63-year-old hypertensive woman with a prolapsing mitral valve developed sudden blindness of the left eye secondary to a central retinal artery embolus. The decision to perform carotid arteriography led to discovery of an ulcerated plaque in the left internal carotid artery, which was found at the time of endarterectomy to bear a large friable platelet thrombus. The frequent occurrence of mitral valve prolapse in normal populations suggests that this anomaly may be incidental rather than etiologic in patients with cerebral embolic phenomena. The finding of mitral valve prolapse should not routinely exclude evaluation for other sources of embolic stroke.
 ...
PMID:Carotid-retinal embolism with coexistent mitral valve prolapse. 719 47

A case of cortical blindness resulting from a dense ischemic lesion of both calcarine cortices (as seen on CAT Scan) was studied up till the seventh month after the initial stroke. By using mainly forced-choice procedures, similar to those previously used for testing hemianopic subjects, we were able to demonstrate the reappearance of some visual capacities, even though the patient still behaved as if completely blind in everyday life and the lesion remained as it was first seen. First, an ability to detect moving stimuli reappeared then bright flashes could be detected. At last, the patient could localize flickering spots approximately, by pointing with his hand, despite the fact that he did not really see them. As was hypothesized in cases of unilateral occipital lesions, such residual vision would likely to be subserved by extrageniculostriate pathways.
 ...
PMID:Residual visual capacities in a case of cortical blindness. 722 57

The results in 57 consecutive patients treated with carotid ligation for an intracranial aneurysm were analyzed to define the risks of late complications. The average age for the group was 46 years. Eighty percent of the aneurysms were located on the internal carotid artery (ICA). The acute morbidity and mortality of the treatment and the natural history of the disease was 29%. Twenty-four patients were discharged with a common carotid artery (CCA) ligation, and 21 patients with an ICA ligation. Three patients from each ligation group could not be located for review. The follow-up period for the 21 patients with CCA ligation ranged from 1 to 15 years, with an average of 8.4 years, and for the 18 patients with ICA ligation it ranged from 2 to 19.5 years, with an average of 12.5 years. Excluding deaths from unrelated causes, five of the 21 patients with CCA ligation developed a late complication. Two patients had a transient ischemic attack (TIA). Two patients had a subarachnoid hemorrhage (SAH), one of which was fatal and was preceded by a TIA. Two patients developed monocular blindness. None of the patients had a stroke. Excluding deaths from unrelated causes, five of the 18 patients with ICA ligation developed a late complication. One patient had a fatal SAH. Three patients had a TIA, two of which were followed by a stroke. One patient had a stroke in the cerebral hemisphere contralateral to the side of the carotid ligation.
 ...
PMID:Late complications of carotid ligation in the treatment of intracranial aneurysms. 722 97

Twenty-five patients with biopsy-proven giant cell arteritis (GCA) were treated at the Royal Adelaide Hospital from 1973 to 1978. Three patients had a normal ESR on presentation. Four patients developed monocular blindness, one had gangrene of the tongue, and one had a brain-stem stroke. Six patients had concurrent autoimmune thyroid disease, one suffered from myasthenia gravis and one had ulcerative colitis--a significant observation in view of the suggestion that GCA has an immunological basis.
 ...
PMID:Giant cell arteritis. A five-year review of biopsy-proven cases in a teaching hospital. 739 75

The epidemiological transition has brought an increasing burden of chronic non-communicable disorders to middle- and even low-income countries. This paper reviews the problem with particular reference to non-insulin-dependent diabetes mellitus (NIDDM) in the English-speaking Caribbean region. Surveys conducted over the last three decades have documented a high prevalence of NIDDM in a number of communities and evidence has accumulated to support the control of obesity and physical inactivity in the primary prevention of non-insulin-dependent diabetes. The problem of introducing and monitoring suitable interventions on a long-term basis in high-risk populations in different cultures has yet to be addressed. The impact of diabetes on health status in developing countries has not been well documented but it is clear that there are high levels of acute illness from disorders of glycaemic control, long-term disability from blindness and limb amputation and premature mortality from stroke, coronary heart disease and renal disease. Present evidence suggests that improving the quality of preventive clinical management can be the most immediately productive approach to controlling health problems from diabetes. Achieving this objective within the social, organizational and resource constraints of the Caribbean presents a range of problems. Identifying the most cost-effective means of improving existing services is therefore the most immediate research priority for NIDDM in the English-speaking countries of the Caribbean.
 ...
PMID:Controlling non-insulin-dependent diabetes mellitus in developing countries. 755 52

Giant cell arteritis (GCA) is an autoimmune condition with a predilection for the arteries of the head and neck. Because GCA may lead to permanent blindness, stroke, or death, it is critically important for all health care personnel, in particular ophthalmic nurses, to know about the presentation, diagnostic methods, and treatment modalities related to this disease. Prompt intervention may save a life.
 ...
PMID:Giant cell arteritis. 758 45

Pituitary adenoma apoplexy was considered an acute life-threatening condition until more benign and even asymptomatic courses were found by advanced neuroimaging procedures. Necrosis and hemorrhage in the pituitary adenoma can cause acute enlargement of the tumor. sometimes with rupture of the tumor capsule and bleeding into the subarachnoid space and surrounding parts of the brain. Clinical symptoms include acute or subacute headache in combination with signs of meningeal irritation and neuroophthalmological and cerebral dysfunction. Severe panhypopituitarism may be an additional complication. Acute blindness due to compression of the optic chiasm and symptomatic compression of basal cerebral arteries require immediate transsphenoid tumor resection. If panhypopituitarism is suspected, immediate hormone substitution is necessary.
 ...
PMID:[Adenomatous hypophyseal apoplexy. Clinical, diagnostic and therapeutic aspects of a frequently misdiagnosed emergency state]. 778 16

We present a rare case of cerebrovascular accident involving non-cardiac, non-neurological, non-carotid surgery in a 44-year-old man with no cardiovascular risk factors who underwent retroperitoneal resection of a teratocarcinoma, immediately after which he showed signs of confusion accompanied by cortical blindness. Neurological signs and symptoms remitted completely 5 days after surgery. Complementary tests and the patient's evolution confirmed a diagnosis of reversible ischemic neurological deficit.
 ...
PMID:[Postoperative cortical blindness after resection of a retroperitoneal teratoma]. 779 17

In the Commonwealth of Dominica, the health and disability status of 108 people who, for various reasons, are confined to their homes--the so-called "shut-ins"--were studied. Eighty per cent of them were over 65 years of age and 10% were children. Most shut-ins were independent in self-care but dependent in general activities. Their overall health was poor. Twenty-one suffered from diseases of the musculo-skeletal system c.q. osteoarthritis, 13 from blindness of various origins, 13 from neurological diseases, 13 from CVA, psychosis or dementia and 13 from different other diseases. One-third suffered from more than one disease. A special programme would be required to optimize the home-care for the shut-ins and to encourage them to become more active.
 ...
PMID:Health status of shut-ins in the Marigot Health District, Commonwealth of Dominica. 781 46


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>