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Query: UMLS:C0038454 (stroke)
 147,016 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Progressive aphasia (PA) caused by neurodegenerative diseases is much less prevalent than aphasia following vascular brain lesions. Clinically, the progressive aphasias can be divided in progressive non-fluent aphasia, semantic dementia and logopenic aphasia. Differential diagnosis is based on a detailed language assessment and neuroimaging. Compared with the therapy of aphasia following stroke the treatment of patients with PA has been neglected. However, recently potential therapeutic options have been evaluated regarding feasibility and efficacy.
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PMID:[Chronic progressive aphasia]. 1970 92

Spelling - a core language skill - is commonly affected in neurological diseases such as stroke and Primary Progressive Aphasia (PPA). We present two case studies of the same spelling therapy (learning of phoneme-to-grapheme correspondences with help from key words) in two participants: one who had a stroke and one with PPA (logopenic variant). Our study highlights similarities and differences in the time course of each indivdual's therapy. The study evaluates the effectiveness and generalization of treatment in each case, i.e. whether the treatment affected the trained items and/or untrained items, and whether or not the treatment gains were maintained after the end of therapy. Both participants were able to learn associations between phonemes and graphemes as well as between phonemes and words. Reliable generalization to untrained words was shown only for the participant with post-stroke aphasia, but we were not able to test generalization to untrained words in the individual with PPA. The same spelling therapy followed a different time course in each case. The participant with post-stroke aphasia showed a lasting effect of improved spelling, but we were unable to assess maintenance of improvement in the participant with PPA. We discuss these differences in light of the underlying nature of each disease.
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PMID:Spelling intervention in post-stroke aphasia and primary progressive aphasia. 2271 3

In this article, we explore the symptoms, cause, treatment potential, and supportive services for individuals diagnosed with Primary Progressive Aphasia (PPA). Although it is possible to regain certain cognitive abilities with stroke or brain injury, in PPA, language abilities worsen and other symptoms emerge with time, shortening the lifespan. The goal of speech therapy for PPA is not to regain lost language, but rather to maximize communication for as long as possible. In this article, we offer information and tools for speech-language pathologists to help people living with PPA achieve these goals and improve overall quality of life.
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PMID:Thinking Outside the Stroke: Treating Primary Progressive Aphasia (PPA). 2650 Jul 14