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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Anterior segment ischemia changes can occur without detachment of any muscles. The most common cause of such ischemic changes of the anterior segment is the removal of too many rectus muscles in one operation. Twenty dog eyes and eight monkey eyes were subjected to the disinsertion and detachment of various combinations of extraocular muscles. They were sacrificed at intervals from 30 to 90 days. During the observation period, they were observed for gross and slit lamp changes. The enucleated eyes were studied microscopically for signs of ischemic and necrotic changes. Two patients who were studied, observed, and treated for anterior segment ischemia following muscle surgery are described. The changes which occur after muscle surgery are extensive and include corneal edema, cataract, chemosis, corneal changes, decreases in intraocular pressure, decreases in outflow or glaucoma and frank necrosis. The variables which lead to this reaction is described in detail. Also, some unanswered queries, such as the duration of the reaction and the time interval of the reaction after multiple muscle surgeries, are discussed.
J Pediatr Ophthalmol Strabismus
PMID:Production of anterior segment ischemia. 10 21

Fornix conjunctival incisions in strabismus surgery may provide partial protection against anterior segment ischemia by preserving the perilimbal conjunctival-Tenon's circulation, which is disrupted with limbal conjunctival incisions. Six adult cynomolgus monkeys underwent tenotomies of three or four rectus muscles by making limbal conjunctival incisions in one eye and fornix incisions in the other. Iris fluorescein angiography and slit-lamp biomicroscopy were used to monitor changes. The eyes that had limbal incisions exhibited more severe anterior segment ischemic changes than the eyes that had fornix incisions in every instance of four rectus muscle surgery.
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PMID:A primate model of anterior segment ischemia after strabismus surgery. The role of the conjunctival circulation. 232 23

Classical galactosemia due to a deficiency of galactose-1-phosphate-uridyl transferase, is an autosomal recessive disorder of galactose metabolism with an incidence in Ireland of one in 30,000 births. It can result in cataract formation through the accumulation of galactitol within the lens. Seventeen children with transferase deficient galactosemia were studied. Early diagnosis followed by a galactose-free diet and tight biochemical control prevented cataract formation in 13 cases after a mean follow-up of 6.3 years. Cataracts did not regress in all patients commenced on diet by 6 weeks but early treatment prevented progression. The ophthalmologist may play an important role in the monitoring of patients with this disease as the recognition of new lens opacities by slit-lamp biomicroscopy may be the most sensitive initial index of inadequate biochemical control.
J Pediatr Ophthalmol Strabismus
PMID:Ophthalmic findings in classical galactosemia--a screened population. 276 Jul 88

To better characterize the appearance of the iris at birth, we studied certain iris features of 100 normal newborns with slit lamp biomicroscopy. We noted the iris color, crypt-structure, and vascularity of the collarette and periphery of the iris. These features were considered in light of the child's birthweight, postnatal days of age, sex, and race. Iris vascularity correlated significantly with postnatal age at examination, and stage of crypt development was more advanced in males, and more evident in the blue and gray irides. Males also had a more advanced stage of iris development. In addition to our previous finding that iris vessels of cocaine intoxicated neonates were more tortuous and dilated than a control group, this study suggests that such vessels may also be more commonly found in sickly infants.
J Pediatr Ophthalmol Strabismus
PMID:Characteristics of the iris in 100 neonates. 291 8

Multiple modalities of treatment for traumatic hyphema have been advocated in the past. Therapy should be directed at reducing the risk of secondary hemorrhage and the potentially devastating complications of corneal blood staining and optic atrophy. Therapeutic regimens proven successful include: a patch and shield to the traumatized eye; daily visual acuity and slit-lamp biomicroscopy, including intraocular pressure, evaluation of corneal clarity, and size of hyphema; topical atropine; the systemic administration of aminocaproic acid; and topical and systemic antiglaucomatous medications with elevated intraocular pressure. Surgical intervention should generally be avoided in hyphemas of less than 50%. In larger hyphemas, there are definite indications for surgical intervention. Preferred surgical methods include: irrigation and aspiration, and hyphema evacuation by vitrectomy instrumentation.
J Pediatr Ophthalmol Strabismus
PMID:Traumatic hyphema. 395 78

Kawasaki disease or mucocutaneous lymph node syndrome is an acute febrile illness primarily affecting children. The principal signs and symptoms recognizable during the acute phase of the illness are described. Kawasaki disease is fatal in up to 3% of cases due to cardiac complications secondary to a systemic vasculitis. In a prospective series, ophthalmologic examinations on 10 children with Kawasaki disease showed that eight had anterior uveitis during the acute phase of the illness. All cases resolved within two to eight weeks. Because of these findings, 15 patients who had had Kawasaki disease with documented bilateral conjunctival injection, but who had never undergone slit-lamp examinations, were recalled for ophthalmologic evaluation. Results of these follow-up examinations were normal in all 15 children.
J Pediatr Ophthalmol Strabismus
PMID:Eye involvement in Kawasaki disease. 729 13

One hundred forty Chinese children with Down syndrome (DS) treated in the Child Assessment Centre of the Duchess of Kent Children's Hospital in Hong Kong between 1985 and 1996 underwent a detailed ophthalmologic evaluation, including test of visual acuity by behavioral testing or retinoscopy, determination of ocular motility, visual field examination, binocular examination for strabismus, determination of near point convergence and pupillary reflex, and/or slit lamp bimicroscopy and ophthalmoscopy to assess ocular health. Only 43 children (31%) had no ocular abnormalities. The overall incidence of ocular abnormalities was 69%, and included refractive error (58%), strabismus (20%), nystagmus (11%), blepharitis/conjunctivitis (7%), lens opacities (4%), and glaucoma (0.7%). No child had Brushfield spots or keratoconus. The incidence of refractive errors increased with increasing age and nearly doubled at school age. As compared with white children with DS, the Chinese children with DS exhibited a higher incidence of refractive error and a similar incidence of lens opacities but a lower incidence of strabismus, nystagmus, blepharitis, Brushfield spots, and keratoconus. Regular visual surveillance, especially of visual acuity, in children with DS as they mature is important in preventing amblyopia.
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PMID:Ocular abnormalities in Down syndrome: an analysis of 140 Chinese children. 925 64

Conjunctival cysts may be congenital or acquired. A common cause of acquired conjunctival inclusion cysts is the implantation of conjunctival epithelium after surgery or trauma. These cysts often form at the site of muscle reattachment after strabismus surgery. They may disappear spontaneously, but persistent cases often require surgical excision. We report a new technique using cauterization under slit-lamp visualization to treat conjunctival inclusion cysts that can form after strabismus surgery. This procedure is fast, effective, and well tolerated by patients.
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PMID:Thermal cautery as a treatment for conjunctival inclusion cyst after strabismus surgery. 1118 73

Suppression in strabismus is more likely to occur when the images for the left- and right-eye are similar. In this study the relationship between the depth of strabismic suppression and the amount of dissimilarity between the images was quantified. Six subjects with microstrabismus looked at two identical colorful, cartoon images via mirrors. In the middle of each screen was a circular aperture with an opal glass, which was illuminated from the back by a halogen lamp during 300 ms with a gradual on- and offset in intensity. In the circular aperture images that slightly differed in shape were presented to both eyes. The dominant eye was presented a circle, the squinting eye a circle that, in four steps, changed its shape into a square. Under each of these four conditions, the image for the dominant eye was attenuated progressively by neutral density filters. When the image for the squinting eye was perceived, the depth of the suppression was thereby measured. It was found that suppression decreased with dissimilarity of the images.
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PMID:Strabismic suppression depends on the amount of dissimilarity between left- and right-eye images. 1216 May 72

Slit-lamp and dilated fundus examination of a 6-year-old boy revealed bilateral anterior uveitis associated with optic disk edema with mild leakage on fluorescein angiography in both eyes. Anterior uveitis resolved with topical therapy in 3 months and optic disk edema and fluorescein leakage 1 month later. Optic nerve function was intact. Resolution of optic disk edema followed that of anterior uveitis with no sequelae.
J Pediatr Ophthalmol Strabismus
PMID:Bilateral papillitis associated with bilateral anterior uveitis in a child. 1806 96


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