Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A mentally retarded child with an extra small bisatellited acrocentric chromosome is described. The patient exhibited rather unspecific clinical signs such as strabismus, marked facial asymmetry, broad and prominent nasal bridge, hypertelorism, Brushfield's spots, malformed ears with atresia of the external auditory canal on the right side. Giemsa banding (R and G methods) did not allow a clear cytogenetic identification of the extra-chromosome. A tentative interpretation of the cytogenetic aberration as a trisomy of the proximal part of the long arm of chromosome 13 is discussed.
Humangenetik 1975 Sep 20
PMID:A case of extra small acrocentric bisatellited chromosome in a non mongoloid child. 118 8

The authors report on the possibilities for examination of the stereoscopic vision at 2 or 4 meters by the phase-difference-haploscope. Besides a gross-qualitative test, methods of estmating realdepth acuity are described. There is a great variability of test-conditions for special scientific problems. During the routine examintion of disturbed binocular vision it is possible to test the stereo acuity, even if there is squint or aniseiconia.
Klin Monbl Augenheilkd 1975 Sep
PMID:[Examination of stereoscopic vision with the phase-difference haloscope (author's transl)]. 121 20

The valuation of 541 cases of convergent squint occuring together with a hypermetropia of more than +5 dpt showed that, the stronger the hypermetropia was, the higher was the proportion of primary microstrabismus to full-accommodative strabismus convergens. In patients who had hypermetropia of more than +8 D, the proportion of primary microstrabismus was 46%. Here the squint was always one-sided, so a high proportion of amblyopia could be expected. In 10% of the cases there was a spontaneous change from convergent to divergent squint - the angle reduction was up to 23 degrees, and could occur at any age. Factors, which seem to favour the appearence of a consecutive divergence, are: high hypermetropia of more than +8 D, increased ACA-ratio, onesided exclusion and vertical divergence. The measuring of the ACA ratio should be done at all orthoptic examinations.
Klin Monbl Augenheilkd 1975 Sep
PMID:[Converging squint in severe hypermetropia (author's transl)]. 121 27

Report of 2 cases of Rubinstein-Taybi-syndrome. Description of the well known symptoms: Mental and somatic retardation, broad thumbs and toes, highly arched palate, retarded bone age, fine hair on limbs. Besides that there were eye abnormalities: Antimongoloid slant, strabismus, ametropia, monolateral ptosis, papillatrophia, latent nystagmus. Discussion of the differential diagnosis.
Klin Monbl Augenheilkd 1975 Sep
PMID:[Ocular symptoms in Rubinstein-Taybi-syndrome (author's transl)]. 121 29

Two hundred children who were of very low birth weight (VLBW) (1500 g or less) and 193 controls who were of normal birth weight (NBW) were examined at approximately 9 years of age. Binocular visual acuity of 6/6 or better was noted in 178 (89.5%) VLBW children and 189 (97.9%) NBW children. Visual morbidity was significantly higher among VLBW children. Strabismus was present in 38 (19%), cicatricial retinopathy of prematurity in 13 (6.5%), and optic atrophy in six (3%) children in this group. Children who were VLBW were also more myopic than the NBW controls. Optic atrophy was frequently associated with cerebral dysfunction. Regular assessments to identify ocular abnormalities in children who were VLBW are recommended.
Br J Ophthalmol 1992 Sep
PMID:Controlled study of ocular morbidity in school children born preterm. 142 53

ROP is a common disorder among extremely low-birth-weight premature infant survivors and may cause total vision loss in as many as 2% to 4% of those weighing less than 2 lb (1 kg) at birth. Regular examinations begun in the intensive care unit permit early detection and treatment of progressive ROP, reducing visual impairment. Ongoing research into antioxidants, angiogenesis, light exposure, and newer surgical techniques may offer new approaches for preventing and treating established ROP. Infants who have had ROP that regressed should continue regular ophthalmologic follow-up to detect and treat myopia, strabismus, and if they have cicatricial sequelae, late retinal detachments as teens or adults. Infants who develop retinal detachments should be referred for early intervention and special education programs and remain in regular ophthalmologic follow-up for the detection and treatment of further ophthalmic complications.
Curr Probl Pediatr 1992 Sep
PMID:Retinopathy of prematurity. 142 57

Agreement between maternal interview- and medical record-based gestational age was assessed by using data from a case-control study of childhood strabismus. The sample consisted of 383 cases of strabismus and their age-matched controls, diagnosed between 1985 and 1986 in Baltimore, Maryland, who were under age 7 years when diagnosed. Medical record-based gestational age was derived, in order of priority, from early ultrasound examination, time from the last menstrual period, pediatric examination, and obstetric examination. The intraclass correlation coefficient, kappa, and mean difference were used to compare agreement between maternal interview- and medical record-based gestational age by maternal and pregnancy characteristics and characteristics related to study design. Overall, 86 percent of mothers were within 2 weeks of the gestational age reported in the medical record. The intraclass correlation coefficient comparing maternal and medical record-based gestational age was 0.83 (95% confidence interval 0.80-0.86). Agreement was positively associated with shorter length of recall, low birth order, and having a neonatal illness related to prematurity. Agreement was poor among mothers of healthy preterm infants. There was a weak positive association between recall and some sociodemographic covariates. There was greater misclassification of prematurity in the controls than in the cases. The results suggest that, in general, women recall gestational age well, which supports the use of gestational age derived from maternal interviews.
Am J Epidemiol 1992 Sep 01
PMID:Agreement between maternal interview- and medical record-based gestational age. 144 20

A prospective, randomized controlled study (n = 95) was conducted to compare the morbidity and length of hospital stay associated with retrobulbar neuromuscular blockade (LA) with that associated with general anesthesia (GA) for monocular strabismus surgery in adult patients. A scoring system was developed to assess postoperative nausea and vomiting, pain, level of consciousness, oral intake, and activity while in the hospital and for the first 3 postoperative days. There was no significant difference in the postoperative nausea and vomiting associated with the two anesthetic techniques. Although patients receiving LA experienced less immediate postoperative discomfort (P < .01) and had greater levels of activity (P < .0001) while in the hospital, the discomfort and activity levels of the two groups were similar at home. The LA group was discharged from the hospital sooner (mean, 135 minutes vs 250 minutes; P < .001), allowing more efficient use of hospital resources. Both techniques provided excellent anesthesia for monocular strabismus surgery.
Ophthalmic Surg 1992 Sep
PMID:A prospective, randomized, controlled comparison of retrobulbar and general anesthesia for strabismus surgery. 148 Mar 64

Significant advances regarding understanding the etiology and treatment of retinopathy of prematurity have occurred in the 50 years since its discovery. Nevertheless, there is still a great deal to be learned. In spite of major technological advances in neonatal care, retinopathy of prematurity is a multi-factorial disease and probably cannot be completely prevented. Early intervention in the diagnosis and management of these infants has greatly improved their visual prognosis. Further studies may help pediatricians and neonatologists to understand and control associated risk factors. Ophthalmologists must continue to examine these patients early and follow them closely to control the associated treatable aspects of the disease, such as strabismus and amblyopia.
Early Hum Dev 1992 Sep
PMID:Current concepts in retinopathy of prematurity. 149 65

Six patients were operated on for large subconjunctival cysts that developed up to 35 years after strabismus surgery. In four of these patients the cyst was found to arise between the anterior edge of the muscle and the site to which the muscle had been sutured during previous surgery. The muscle was attached to the posterior wall of the cyst and not to the sclera. A pseudotendon was found running between the point on the sclera to which the muscle had been sutured and the undersurface of the muscle far posteriorly. In the other two patients a sudoriferous cyst was found that the referring ophthalmologist had mistakenly thought to represent an abscess when excision was attempted.
Arch Ophthalmol 1992 Sep
PMID:Subconjunctival cysts as a complication of strabismus surgery. 152 Jan 10


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>