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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We examined the eyes of all infants in our Neonatal Intensive Care Unit from 1979 to 1981 who were premature and/or had exposure to increased ambient oxygen. From these 1,012 neonates, 19 were found to have Grade III or worse acute retinopathy of prematurity (ROP) in at least one eye. We studied the graphic relationship of the mean daily values for blood Pc02, Pa02, PC02, and pH and the production of retinopathy of prematurity in these infants and compared the results with a similar group of infants who had similar birthweight, gestational age and Vitamin E administration. The comparison group patients were in the hospital during this same period of time and did not have Grade III ROP. There was no characteristic level, peak or pattern of these values that could identify or predict which infants would develop ROP.
J Pediatr Ophthalmol Strabismus
PMID:Blood oxygen, carbon dioxide and pH levels prior to diagnosis of retinopathy of prematurity. 392 87

Vitamin E is one of the most important lipid-soluble antioxidant nutrients. Severe vitamin E deficiency can have a profound effect on the central nervous system. Cystic fibrosis, chronic cholestatic liver disease, abetalipoproteinemia, short bowel syndrome, isolated vitamin E deficiency syndrome and other malabsorption syndromes all may cause varying degrees of neurologic deficits due to related vitamin deficiencies. The classic abnormalities in vitamin E deficiency progress from hyporeflexia, ataxia, limitations in upward gaze and strabismus to long-tract defects, profound muscle weakness and visual field constriction. Patients with severe, prolonged deficiency may develop complete blindness, dementia and cardiac arrhythmias. Treatment must be tailored to the underlying cause of vitamin E deficiency and may include oral or parenteral vitamin supplementation. The more advanced the deficits, the more limited the response to therapy. Therefore, a good neurologic examination and periodic serum vitamin E levels are essential in patients at risk of vitamin E deficiency.
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PMID:Neurologic findings in vitamin E deficiency. 901 78