Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038379 (strabismus)
9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A retinal varicosity in the Klippel-Trenaunay syndrome is observed and diagnosed in a 24-year-old female. Fluorescein angiography was used to illustrate and specify the nature of the retinal vascular anomaly.
J Pediatr Ophthalmol Strabismus
PMID:Retinal varicosity in Klippel-Trenaunay syndrome. 23 Mar 32

The clinical features and fluorescein angiographic findings of an 18-year-old man with PHPV are reported. The case is unusual in that the eye survived into adulthood. The lens resorbed spontaneously, thereby permitting study of the retrolental mass by fluorescein angiography. Fluorescein leakage from the persistent vessels was very slow but present, thus indicating a probable disruption of the endothelial tight junctions of the tunica vasculosa lentis.
J Pediatr Ophthalmol Strabismus
PMID:Persistent hyperplastic primary vitreous in an adult: case report with fluorescein angiographic findings. 73 54

Five patients who had had neonatal herpes simplex virus infection were re-examined at ages that varied from 6 to 9 years. In all of them the diagnosis had been supported by virus isolation and antibody titration, and herpes virus type 2, the genital strain, had been the causative agent. Only 1 of the patients was mentally retarded. Three of the patients had manifest squint, and only 1 patient had normal visual acuity in both eyes. The fundus changes varied from atrophy of the retinal pigment epithelium in 3 patients to atrophy of the optic disc in 2 eyes and extreme tortuosity of the retinal arterioles and veins in 1 patient. One patient developed bilateral retinitis with exudation into the vitreous at the age of 5 years. Fluorescein angiography of this patient showed peripheral vascular closure and preretinal neovascularisation, with leakage in both eyes. This may have been due to chronic retinal vasculitis; haemorrhagic infarction may have induced the damage to retinal tissues. Laser photocogulation resulted in slight improvement of the visual acuity, clearing of the vitreous, and decrease of the fluorescein leakage.
...
PMID:Late ocular manifestations in neonatal herpes simplex infection. 92 25

Strabismus surgery results in the permanent interruption of anterior ciliary blood flow, predisposing the eye to anterior segment ischemia (ASI). A primate model was used to assess the effectiveness of a new muscle-scleral tuck for preserving anterior ciliary artery circulation. The model consisted of removing 3 rectus muscles from both eyes of 2 rhesus monkeys, then performing a tuck on the inferior rectus (IR) right eye while leaving the left IR as a control. Four weeks later, a modified tuck was performed on the virgin left IR. Fluorescein iris angiograms of both eyes were obtained, and preoperative angiograms at 5-15 sec. showed normal 360 degrees perfusion. Postoperative follow-up angiograms showed segmental superior temporal filling defects and preservation of perfusion in the distribution of the IR. Comparison of fellow eyes tucked vs control IR showed no difference in the filling pattern in both monkeys. Comparison of the same eye before and after tuck also showed essentially the same filling pattern in all 4 eyes with preservation of inferior circulation. Our conclusion is that the modified tuck preserves the anterior ciliary blood flow and may be useful as a muscle-strengthening procedure in patients predisposed to developing ASI.
...
PMID:Effect of a modified rectus tuck on anterior ciliary artery perfusion. 194 98

Removal of a rectus muscle results in permanent interruption of blood flow in the corresponding anterior ciliary artery, predisposing to anterior segment ischemia (ASI). A subhuman primate model of ASI was developed in order to study a novel muscle tuck procedure designed to preserve anterior ciliary artery circulation. Fluorescein angiograms were obtained before and after surgery to determine the effect of the muscle surgery on iris circulation. A total of 12 eyes from 12 cynomolgus monkeys underwent strabismus surgery consisting of tenectomy of all 4 rectus muscles in 3 eyes, tenectomy of 3 rectus muscles in 3 eyes, and tenectomy of 3 rectus muscles and muscle to sclera tuck of the remaining recti in 6 eyes. Postoperative angiograms documented preservation of perfusion in the distribution of the tucked muscle in all cases except one, in which there was iatrogenic trauma and disruption of anterior ciliary arteries. The modified tuck procedure thus appears to preserve anterior ciliary artery blood flow, and may be useful as a muscle strengthening procedure in patients predisposed to developing ASI.
J Pediatr Ophthalmol Strabismus
PMID:Effect of a modified rectus tuck on anterior segment circulation in monkeys. 205 Dec 93

Seven children who had undergone removal of congenital cataracts were evaluated postoperatively for cystoid macular edema during outpatient visits. Fluorescein was administered orally in a fruit juice cocktail, and the eyes examined by angioscopy 10-20 minutes and 45-60 minutes after dye ingestion. No evidence of macular leakage was observed in any of the 11 eyes examined. It appears that this diagnostic procedure is feasible in young patients, and that the incidence of cystoid macular edema after congenital cataract extraction may be less than has been previously reported.
J Pediatr Ophthalmol Strabismus
PMID:Oral fluorescein angioscopy in aphakic children. 670 56

A patient with IgA nephropathy developed cotton-wool spots and serous retinal detachments. Fluorescein angiography demonstrated choroidal infarcts in both eyes from hypertensive retinopathy in acute on chronic renal failure. Plasmapheresis and hemodialysis led to visual recovery. Acute ocular hypertensive changes from IgA nephropathy may be reversed by plasmapheresis and hemodialysis.
J Pediatr Ophthalmol Strabismus
PMID:Ocular findings in IgA nephropathy with renal failure and hypertension. 1716 79

A 3-year-old boy was referred because of the presence of a non-pigmented, highly vascular mass with tapioca appearance involving the superior portion of the left iris. Iris fluorescein angiography revealed early hyperfluorescence of the iris tumor with diffuse, intense late leakage of dye throughout the entire iris, not just in the region of the tumor. Cytopathologic examination revealed Touton giant cells and the presence of histiocytes, confirming the diagnosis of iris juvenile xanthogranuloma. The patient was prescribed topical prednisolone acetate, and the lesion resolved during the next 3 months. Fluorescein angiography may be useful in differentiating iris juvenile xanthogranuloma from malignant or non-inflammatory benign iris lesions.
J Pediatr Ophthalmol Strabismus
PMID:Fluorescein angiography of iris juvenile xanthogranuloma. 1840 59

A 20-year-old man who had progressive hemifacial atrophy was examined using fluorescein and indocyanine green angiography. The fundus showed sectional chorioretinal atrophy. Fluorescein angiography showed window defects without leakage. Indocyanine green angiography revealed narrow choroidal vessels with hypofluorescence.
J Pediatr Ophthalmol Strabismus
PMID:Fluorescein and indocyanine green angiographic findings in progressive hemifacial atrophy. 1921 82

A 17-month-old girl referred for a suspected ciliary body medulloepithelioma was found to have persistent fetal vasculature. Fluorescein angiography showed perfused hyaloid artery posterior tunica vasculosa lentis with brittle star appearance and nonperfused anterior pupillary membrane. Ultrasound biomicroscopy confirmed absence of iris or ciliary body solid tumor.
J Pediatr Ophthalmol Strabismus 2014 Nov 19
PMID:Posterior tunica vasculosa lentis and "brittle star" of persistent fetal vasculature. 2540 59


1 2 Next >>