Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The records of 48 patients with congenital nystagmus who required surgery for a significant head turn were reviewed to compare the effectiveness of the surgical techniques. Patients were omitted from the study if the last postoperative visit was less than five months following surgery, or if the surgery was for a vertical head posture. The average preoperative head turn of the 38 patients with horizontal nystagmus was 41.3 degrees with an average postoperative head turn of 11.5 degrees. The net change in head turn was 33.4 degrees. The average duration of time from surgery to final examination was four years and six months. The study was divided into six groups of patients. The first group received the Parks modification of the standard Kestenbaum procedure, the 5-6-7-8 millimeter procedure. The second group received the above procedure plus 1 mm additional surgery. The third group received another modification by Parks of 6.5-8-9-10 millimeters. The fourth group received the Calhoun and Harley modification of 40% augmentation of the original Parks recommendation, and the fifth group received 60% modification. The sixth group required more than one procedure on the horizontal recti for the abnormal head posture. The pre- and postoperative measurements are compared for each of these six groups. In some patients followed for many years, there is a tendency for a gradual return toward the preoperative head posture. In four patients in the study, the gaze preference was shifted to the opposite direction postoperatively.
J Pediatr Ophthalmol Strabismus
PMID:Kestenbaum surgical procedure for torticollis secondary to congenital nystagmus. 358 58

In a series of 24 patients with Turner's syndrome, amblyopia was found to be present in ten (41.6 per cent), strabismus in nine (37.5 per cent), hypermetropia in ten (41.6 per cent), ptosis in seven (29.1 per cent), and bilateral epicanthus in eleven (45.8 per cent) cases. Turner (1938) described a syndrome of infantilism, congenital webbed neck, and cubitus valgus, which has come to be known as Turner's syndrome. Since then many cases have been reported and multiple other associated features have also been recognized. Isolated ocular features have been mentioned in some sporadic case reports (Cunningham and Harley, 1951; Laurent, Royer, and Noel, 1961; Lessell and Forbes, 1966; Khodadoust and Paton, 1967; Szymanska and Szymanski, 1976; Troupe and Troupe, 1981). So far no significant series of cases has been studied to assess the ocular defects. This report of a series of 24 patients presents classified ophthalmic features.
 ...
PMID:Ocular manifestations of Turner's syndrome. 696 61

Fibrosis of the extraocular muscles can be congenital or acquired. Acquired causes include trauma, myositis, thyroid eye disease, infection, and metastases. Congenital fibrosis of the extraocular muscles (CFEOM) runs in families and is known to have a genetic basis. It has been classified by Brown, Hansen, and Harley et al into the five following types: general fibrosis syndrome; fibrosis of the inferior rectus (IR) with blepharoptosis; strabismus fixus; vertical retraction syndrome; and unilateral fibrosis, blepharoptosis, and enophthalmos syndrome. In this report, a case of unilateral fibrosis with enophthalmos and blepharoptosis due to a fibrous band is described.
 ...
PMID:Unilateral restrictive ophthalmoplegia and enophthalmos associated with an intraorbital tissue band. 1772 May 74