Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An oil painting of a blind old English soldier done by James Ramsay in 1830 allows for some interesting thoughts about the use of symbolism in art and about the nature of blindness.
J Pediatr Ophthalmol Strabismus
PMID:The blind soldier: a study dealing with the symbolism of blindness in art. 8 7

Three documented cases of subperiosteal hematomas in the region of the orbital roof of young males are used to demonstrate the unpredictable appearance, the obscure nature, the complications and the treatment of this process. One case occurred in a 14-year-old boy following blunt head trauma and was cured by aspiration. The second case, in a 16-year-old boy, also resulted from blunt head trauma; it was associated with a large subgaleal hematoma and caused permanent blindness of the involved eye. The third case developed in an 18-year-old male as a complication of acute purulent endophthalmitis following an intraocular foreign body. The aim of this study is to separate subperiosteal hematomas and to show that it is a concise clinical entity with its own typical history, appearance and treatment.
J Pediatr Ophthalmol Strabismus
PMID:Subperiosteal hematomas of the orbit in young males: a serious complication of trauma or surgery in the eye region. 51 84

Careful evaluation of all parameters of ocular function are required to delineate the cause of lack of visual responses in children. Any visual fixation, no matter how fleeting, is a sign of intact visual pathways. If no sign of ocular pathology can be found on the routine exam of the visually inattentive child, electrophysiologic testing may be necessary to confirm the presence of abnormality of the visual pathways. In the child with a generalized CNS disorder, the lack of visual response may be due to his inability to respond to visual information (perceptual blindness) rather than to organic pathology in the occipital cortex (cortical blindness).
J Pediatr Ophthalmol Strabismus
PMID:Can my child see? The evaluation of visual function in children. 51 90

The eyes of 1 466 children (88.3% of the total) who were admitted to the Centre for premature babies and the neonatal intensive care unit at Rennes between 1973-1975 were re-examined at the age of 2 years. There were 839 premature and 226 term babies whose weight was appropriate for gestational age, and 74 premature and 327 term babies who were small for dates. 95 (6.5%) had eye disorders at the age of 2. Abnormalities were more common in infants with a Birth weight of less than 1 500 g and in those with a gestional age of less than 28-30 weeks. Boys were more commonly affected than girls. 38% of the children with eye disorders had other problems of which the commonest was mental retardation (75%). There was no relation between perinatal complication and the incidence of eye disorders. The most common abnormality was squint (94%) but other problems were major (blindness, cataracts, retrolental fibroplasia). 37% of the abnormalities had not been diagnosed until found in the survey at the age of 2 years.
 ...
PMID:[Ophthalmologic evaluation at the age of 2 years of newborn infants hospitalized in the neonatology center at Rennes]. 53 46

The familial occurrence of retinal dysplasia in five affected male children suggested X-chromosome-linked recessive inheritance. The clinical features were childhood onset, severe visual impairment, head posture, nystagmus, and strabismus. The ophthalmoscopic findings varied in shape and extension; they ranged from retinal folds to dysplastic tissue covering the posterior pole or gliosis with tumor-like protrusion in the vitreous. The marked variability of the retinal findings was paralleled by the visual acuity, which ranged from some vision to blindness. Electroretinograms coordinated well with ophthalmoscopic observations. Of the five mothers, who are the presumed heterozygous carriers, two showed retinal changes.
 ...
PMID:Primary retinal dysplasia transmitted as X-chromosome-linked recessive disorder. 56 35

A delayed subgaleal hematoma developing after blunt head trauma extended into the right orbit to form a subperiosteal hematoma on the orbital roof. Permanent blindness was found in the involved eye six days after the injury.
J Pediatr Ophthalmol Strabismus
PMID:Posttraumatic subgaleal hematoma extending into the orbit as a cause of permanent blindness. 73 44

Physiological experiments, involving recording from the visual cortex in young kittens and monkeys, have given new insight into human developmental disorders. In the visual cortex of normal cats and monkeys most neurones are selectively sensitive to the orientation of moving edges and they receive very similar signals from both eyes. Even in very young kittens without visual experience, most neurones are binocularly driven and a small proportion of them are genuinely orientation selective. There is no passive maturation of the system in the absence of visual experience, but even very brief exposure to patterned images produces rapid emergence of the adult organization. These results are compared to observations on humans who have "recovered" from early blindness. Covering one eye in a kitten or a monkey, during a sensitive period early in life, produces a virtually complete loss of input from that eye in the cortex. These results can be correlated with the production of "stimulus deprivation amblyopia" in infants who have had one eye patched. Induction of a strabismus causes a loss of binocularity in the visual cortex, and in humans it leads to a loss of stereoscopic vision and binocular fusion. Exposing kittens to lines of one orientation modifies the preferred orientations of cortical cells and there is an analogous "meridional amblyopia" in astigmatic humans. The existence of a sensitive period in human vision is discussed, as well as the possibility of designing remedial and preventive treatments for human developmental disorders.
 ...
PMID:Modification of visual function by early visual experience. 82 72

A study of ophthalmic patients at Harari Hospital indicates that Rhodesian Blacks in Mashonaland constitute a population with interesting ophthalmic features. There is a low incidence of refractive error, with a total incidence of 8,5% of myopia in adults. Functional concomitant squint is uncommon, with an incidence of 0,8% in children under 15 years of age. Non-traumatic, idiopathic primary retinal detachments occur rarely, while secondary retinal detachments occur with low frequency (about 0,55 per 100 000 population per year). Acute and painful congestive angle closure glaucoma is not seen, although chronic angle closure glaucoma is sometimes encountered. Hypertensive retinopathy is not infrequently seen, while diabetic retinopathy is uncommon. Visual loss and blindness from corneal disease are wide-spread. The population has a remarkably low incidence of senile macular degeneration (1,13% of adults over 65 years of age).
 ...
PMID:Impressions of eye diseases among Rhodesian Blacks in Mashonaland. 89 35

The authors investigated 7 children with developmental anomalies of the optic disc. In all cases a typical pattern of hypoplasia was observed. In all patients was found a very marked impairment of visual acuity or even blindness of the affected eye with most frequently squint and nystagmus. Besides ophthalmological investigation, neurological examination were carried out in these children and the Wassermann reaction was determined, together with tests for toxoplasmosis and radiograms of the optic foramina.
 ...
PMID:[Congenital hypoplasia of the optic nerve (author's transl)]. 119 50

An isolated case and an outbreak of parelaphostrongylosis in goats are described. Signs included tetraparesis, hemiparesis, tetraplegia, spastic gait, scoliosis, vestibular strabismus, blindness, and death. Five cases were necropsied and nematodes were seen in the brain and spinal cord of four of these. Intact adult nematodes from two cases were identified as Parelaphostrongylus tenuis, the meningeal worm of white-tailed deer. Cerebrospinal fluid analysis from affected goats showed a moderately elevated protein content, evidence of hemorrhage, and mononuclear cell and eosinophil pleocytosis. Recoveries are recorded.
 ...
PMID:Naturally occurring cerebrospinal parelaphostronglylosis. 125 9


1 2 3 4 5 6 7 8 9 10 Next >>