Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Three hundred sixty hearing-impaired students were screened for visual problems, including Usher's syndrome, with a complete ophthalmologic exam and electroretinography (ERG). Over 25% were found to have a significant refractive error, and approximately 32% had one or more pathologic findings. Overall, 43% either had a significant refractive error or pathologic finding. The incidence of Usher's syndrome was estimated to be between 1.1% and 1.9% in the hearing impaired student population. The results emphasize the need for a complete ophthalmologic examination, and possible ERG testing, in the hearing impaired student population.
J Pediatr Ophthalmol Strabismus
PMID:Screening of school-aged hearing impaired children. 317 28

To determine the nature and prevalence of ophthalmologic abnormalities in children with congenital or prelinguistic sensorineural deafness, we performed complete ophthalmologic examinations on 54 children aged 2 to 14 years from the University of Miami Ear Institute's Cochlear Implant Program. Of 54 children, 33 (61.1%) had some form of ophthalmologic abnormality, with the majority (24 patients; 44.4%) being refractive errors. Of 54 patients, two (3.7%) had strabismus and two (3.7%) had external adnexal anomalies. One child (1.8%) had cataracts. The cause of the deafness, which had previously been unknown, was determined in three of 54 cases (5.6%) as a result of ocular examinations documenting rubella retinopathy, tapetoretinal degeneration (Usher's syndrome), and iris heterochromia (Waardenburg's syndrome). Routine ophthalmologic examination must be mandated for this population, and the ophthalmologist should be encouraged to play a broader role in the care of children with deficiencies of both vision and audition.
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PMID:Ophthalmologic abnormalities in the pediatric cochlear implant population. 802 78

Three cases of Usher syndrome associated with a variant of Dandy-Walker malformation in three siblings from consanguineous Turkish parents are described. The siblings had retinitis pigmentosa and hearing loss. Two of the siblings also had mental retardation, which is not a constant finding in Usher syndrome. Dandy-Walker malformation might have contributed to the mental retardation in two of these patients and might be a coincidental finding with Usher syndrome.
J Pediatr Ophthalmol Strabismus 2010 May 21
PMID:Usher syndrome associated with a variant of Dandy-Walker malformation. 2121 64

Duane retraction syndrome is characterized by globe retraction and palpebral fissure narrowing on adduction, with restriction of abduction, adduction, or both. Usher syndrome type 2 consists of congenital bilateral sensorineural hearing loss and retinitis pigmentosa. The authors present a case with a yet unreported association between Duane retraction syndrome type 1 and Usher syndrome type 2.
J Pediatr Ophthalmol Strabismus 2015 May 07
PMID:Duane retraction syndrome type 1 with Usher syndrome type 2: an unreported association. 2595 20