Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038379 (strabismus)
9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

During a 5-month period, four patients developed contracture of the inferior rectus muscle following local anesthesia for cataract surgery in the practice of one ophthalmologist. Two anesthesiologists administered retrobulbar anesthesia. All patients had persistent vertical diplopia caused by a large hypotropia of the operated eye. Forced duction testing revealed marked restriction to elevation of the eye. In two patients, MRI demonstrated segmental thickening of the inferior rectus muscle, just posterior to the globe. All patients had normal thyroid function tests. No patient had a previous history of strabismus. Three of the four have had strabismus surgery consisting of recession of the markedly restricted inferior rectus muscle on an adjustable suture. These three patients have regained fusion and are now asymptomatic.
J Pediatr Ophthalmol Strabismus
PMID:A cluster of patients with inferior rectus restriction following local anesthesia for cataract surgery. 825 42

We reviewed 67 cases of inferior rectus muscle recession. In 14 cases, the hypotropia was corrected to a satisfactory alignment in the immediate postoperative period followed by a progressive overcorrection (hypertropia). Patients with thyroid eye disease were at highest risk for progressive overcorrection, as 9 of 18 (50%) developed the problem. Patients undergoing adjustable suture were at a higher risk for development of the overcorrection, as 1 of 35 (3%) surgeries done with standard techniques had the overcorrection while 13 of 32 (41%) done on an adjustable suture had the problem. However, the actual act of adjustment was found not to be a predisposing factor. Also, operating upon multiple muscles was found not to be a risk factor for the complication. Once progressive overcorrection occurred, it was more difficult to correct when the patient had thyroid eye disease. We also reviewed 77 consecutive cases of superior, lateral, and medial rectus muscle recessions and found no cases of progressive overcorrection.
J Pediatr Ophthalmol Strabismus
PMID:Progressive overcorrection after inferior rectus recession. 835 Feb 21

We describe a case of disintegration of the inferior rectus muscle during routine strabismus surgery for restrictive hypotropia after cataract surgery. We used this surgical approach to repair the complete infraduction deficit incurred from the injury.
...
PMID:Disintegration of the inferior rectus muscle during strabismus surgery for restrictive hypotropia. 1092 71

Fixation linked hypotropia has rarely been reported. We hereby present two cases of fixation linked hypotropia associated with amblyopia and high myopia in the deviating eye.
Binocul Vis Strabismus Q 2003
PMID:Fixation linked hypotropia in high myopia. A report of two similar cases. 1259 67

We present yet another case of apparent inferior rectus paralysis following retrobulbar anesthesia for cataract surgery. He initially had a typical course but, unusually, after developing hypotropia and presumed contracture, went on to spontaneously recover. We are unaware of any other such case described in the literature. Methods to enhance this more desirable course are considered.
Binocul Vis Strabismus Q 2003
PMID:Spontaneous recovery from inferior rectus contracture (consecutive hypotropia) following local anesthetic injury. 1276 42

The effect of botulinum toxin A is investigated in the treatment of adherence syndrome related to strabismus surgery. An 18-year-old boy with decompensated right congenital fourth nerve palsy underwent ipsilateral superior rectus muscle recession and inferior oblique muscle disinsertion. During the early postoperative period, a right hypotropia with limitation of elevation developed and the result of the forced duction test was positive for passive elevation of the right eye. Botulinum toxin A was injected into the right inferior rectus muscle on the 15th postoperative day and orthophoria was achieved 1 week later. A repeat injection of botulinum toxin A was performed 6 months later. On follow-up 2 1/2 years later, his eyes remained orthophoric with limitation of elevation in the right eye and the patient was satisfied with the result. This case demonstrated that adherence syndrome can be treated successfully by botulinum toxin A injection if it is administered during the acute phase, before the development of fibrous scar tissue.
...
PMID:Botulinum toxin A in the treatment of adherence syndrome. 1450 63

In myopic strabismus fixus, there is acquired esotropia and hypotropia associated with restricted elevation and abduction. One possible etiology is an enlarged globe herniating superotemporally through the muscle cone. High-resolution magnetic resonance imaging (MRI) has demonstrated the inferolateral displacement of the lateral rectus (LR) muscle in this restrictive motility disorder. Surgical treatment is difficult. We report two cases of myopic strabismus fixus that were treated with a loop myopexy of the LR and superior rectus (SR) muscles.
...
PMID:Loop myopexy for treatment of myopic strabismus fixus. 1641 29

We report organoid nevus with left oculo-orbital choristoma fixing the globe in hypotropia, precanthal skin tag, and upper eyelid coloboma and right limbal dermoid. Computed tomography revealed a dilated lateral ventricle and cerebral atrophy. No neurologic deficit existed. The coloboma was repaired, choristoma debulked, and precanthal tag excised.
J Pediatr Ophthalmol Strabismus
PMID:Atypical oculo-orbital complex choristoma in organoid nevus syndrome. 1659 83

We evaluated the one-stage intraoperative adjustment strabismus surgery with adjustable suture under topical anesthesia. Medical records of the patients who had intraoperative adjustment surgery under topical anesthesia for horizontal or vertical strabismus in our hospital from March 1997 to March 2003 with follow-up of 6 months were analyzed retrospectively. Of the 71 patients, 48 patients had exotropia, 16 had esotropia, and 7 had hyper- or hypotropia. The overall success rates were 85.9% at 1 week, 83% at 1 month, 78.9% at 3 months, and 76.1% at 6 months after surgery. The procedure was not stopped in any patients, and no serious intra-operative or postoperative complications were noted. Intraoperative adjustment strabismus surgery under topical anesthesia is a simple, well-tolerated and effective procedure.
...
PMID:Intraoperative adjustment in strabismus surgery under topical anesthesia. 1706 10

Forced duction and generation testing of a patient with Parry-Romberg syndrome (progressive hemifacial atrophy) confirmed that his incomitant hypotropia and esotropia were restrictive and not due to nerve paresis. This suggests that an orbital inflammatory process (causing extraocular muscle fibrosis) is part of this rare and poorly understood syndrome.
J Pediatr Ophthalmol Strabismus
PMID:Restrictive strabismus in Parry-Romberg syndrome. 1727 38


<< Previous 1 2 3 4 5 Next >>