Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Eighty-one unilateral aphakies under 45 years of age, 63 of which had suffered an injury, were analyzed by echometry and intraocular optics. With the aid of a computer, the majority of cases were treated for restoration of nearly equal images in both eyes by combined correction, i.e., an appropriate spectacle -- contact lens combination with both distant and near vision in the aphakie eye taken into consideration. Results with unilateral post-traumatic aphakia (63 cases) : 31 patients with uncorrected vision and 42 with a conventional contact lens suffered from symptoms of binocular confusion as opposed to only one patient with combined correction. Of the 63 patients with uncorrected vision or with a conventional contact lens, 44 had strabismus. After optimal treatment with combined correction, with or without subsegment strabismus surgery, 19 out of 23 patients were cured of their strabismus and regained a useful and comfortable, distant and near binocular vision. Thus, for juvenile unilateral aphakics, a rather good prognosis was achieved by combined correction.
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PMID:[Unilateral aphakia in juveniles. Results of combined correction (author's transl)]. 30 84

The clinical and pathologic findings of a case of congenital bilateral, peripheral corneal leukoma associated with iris coloboma and anterior subluxation of the lens are reported. The changes in the region of keratolenticular apposition include partial absence of Bowman's membrane, stromal vascularization and thinning with large-diameter collagen fibrils, and absence of Descemet's membrane and endothelium. The authors postulate that dysembryogenesis of the tertiary vitreous, with iris coloboma, resulted in apposition of the lens to cornea during the second and third month of gestation and that this apposition resulted in the observed peripheral corneal abnormalities.
J Pediatr Ophthalmol Strabismus
PMID:Peripheral Peters' anomaly: a histopathologic case report. 31 Aug 74

Anterior staphylomas developed in two young patients as a postoperative complication of hyphema extractions through corneoscleral sections. The patients, aged five and nine years, underwent evacuation of the hyphemas after rebleeding caused medically unmanageable intraocular pressure elevations. Postoperatively, both patients received corticosteroids and had elevation of intraocular pressure. To repair the staphyloma, a scleral overlay patch graft was performed in one patient, but the intraocular pressure remained elevated and the staphyloma gradually recurred. Enucleation of the eye was eventually required. Resection of the staphylomatous area with lensectomy and complete vitrectomy was performed in the second patient. After four years of follow-up this patient continues to do well.
J Pediatr Ophthalmol Strabismus
PMID:Staphyloma: a complication of surgery for hyphema. 31 Aug 75

Colour vision in squint amblyopia depends on the fixation modus. In eyes with foveolar or unsteady foveolar from fixation the 3 primary colour vision mechanisms (CVMs) gave normal foveolar CVM patterns. The absolute spectral retinal sensitivity was somewhat, but not significantly lowered. The spectral sensitivity for hue discrimination was either normal, or slightly reduced in the short wavelength side, or slightly reduced over the whole visible spectrum. The spectral sensitivity for saturation discrimination showed normal curves. -- In amblyopic eyes with parafoveal to perifoveal fixation mode the absolute spectral retinal sensitivity is lowered for about 0.45--0.60 log units in comparison to an approximately corresponding excentric retinal area in a normal eye. In eyes with parafoveolar to perifoveal fixation mode measurements of CVMs and of hue discrimination gave better results than could be expected with regard to the position of the fixating area as determined by visuscope. The values correspond to those obtained in retinal areas at least as close to the foveola as the amblyopic fixation point, but usually of an even more central position. The sensitivity for saturation discrimination showed no significant disturbance.
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PMID:[Colour vision in squint amblyopia (author's transl)]. 31 35

The clinical findings in a 16-year-old boy with unilateral isolated pupillary paralysis in a case of herpes zoster ophthalmicus is described because of the extreme rarity of the condition. The condition appeared to be due to a partial third nerve lesion affecting only the fibers subserving the light and near reflexes.
J Pediatr Ophthalmol Strabismus
PMID:Isolated pupillary paralysis in a case of herpes zoster. 31 15

A case of lens dislocation complicating strabismus surgery is described. This complication following scleral perforation is extremely rare. The lens dislocation occurred in the direction of the connective tissue overlying the perforation site to which multiple cryoapplications had been made. Irrigation and aspiration of the clear lens followed by discission of the lens capsule was necessary because of progressive lens dislocation resulting in profound amblyopia. Accurate aphakic optical correction of the involved eye combined with vigorous occlusion of the fellow eye resulted in excellent visual acuity for both eyes. Cosmetic strabismus surgery was then performed. Continued intermittent occlusion of the fellow eye, combined with continued constant aphakic optical correction of the affected eye will be required. The affected eye will be carefully followed for the long-term complication of retinal detachment associated with connective tissue traction.
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PMID:Lens dislocation after strabismus surgery. 31 67

The principal occular complications of chromosomal aberrations are : strabismus, cataract, ptosis, nystagmus. Each of these can benefit from surgical treatment but one has to take into account the unfavorable prognosis due to mental deficiency.
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PMID:[Therapeutic possibilities in occular complications of chromosomal aberrations (author's tansl)]. 31 3

A sibship originally reported by Friedman and Roy as showing severe mental retardation, strabismus, hyperactive tendon reflexes, lalling speech, and foot deformities was restudied. Three major additional findings were noted. The cerebrospinal fluid protein concentration was increased two to three times above normal in four siblings who were available for study. Radiographs of cranial structures in three siblings showed identical pathologic intracranial calcifications which correspond in distribution to the choroid plexus. The choroid plexus was not demonstrable in one patient when radiolabeled 99m-Tc-pertechnetate was injected without perchlorate. Neuropathologic findings in one sibling included small subcortical heterotopias and atrophy of the choroid plexus with encasement by glial fibrils. These findings denote a new heredofamilial neurologic syndrome associated with mental retardation and a disorder of choroid plexus.
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PMID:Familial amentia, unusual ventricular calcifications, and increased cerebrospinal fluid protein. 31 25

A case of retinal disinsertion syndrome in a 31-year-old mentally retarded patient was reported. Associated anomalies included subluxation of the lens, microphthalmos and bilateral keratoconus. Total retinal detachment and subluxation of the lens in a blind microphthalmic eye of a young infant should raise the possibility of retinal disinsertion syndrome.
J Pediatr Ophthalmol Strabismus
PMID:Retinal disinsertion syndrome: report of a case. 31 5

A family is described in which four of six siblings have congenital hereditary corneal dystrophy associated with esotropia. All cases had been erroneously diagnosed as and operated on for congenital glaucoma. The hereditary aspect of this association is discussed.
J Pediatr Ophthalmol Strabismus
PMID:Congenital hereditary corneal dystrophy associated with esotropia. 31 6


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