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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The survival rate of children with localized orbital rhabdomyosarcoma is now greater than 90% 3 years after diagnosis as a result of advances in radiation and chemotherapy. Ninety percent of these children develop cataracts within 1 to 4 years after the completion of radiotherapy. The correction of aphakia in these children is complicated by the concurrent keratoconjunctivitis and dryness associated with radiotherapy. Three patients with a diagnosis of orbital rhabdomyosarcoma underwent treatment for uniocular cataract. Two of the patients were unable to use extended wear contact lenses. Both underwent epikeratophakia with poor results. One patient who had clinically significant ocular drying prior to cataract extraction underwent successful implantation of an intraocular lens as a primary procedure, with excellent visual results. Clinicians should be aware of the difficulties associated with contact lens wear and epikeratophakia tissue lenses in children who have had high doses of radiation for orbital rhabdomyosarcoma. Such patients are probably best served by primary intraocular lens implantation or by preservation of the posterior capsule at the time of cataract extraction to allow secondary lens implantation if contact lens wear is unsuccessful.
J Pediatr Ophthalmol Strabismus
PMID:The correction of unilateral aphakia in children treated for orbital rhabdomyosarcoma. 234 12

A rapidly enlarging periocular mass in a child obligates the treating physician to rule out a malignancy, especially a rhabdomyosarcoma. A 3-year-old girl presented with a 5-day history of a rapidly growing episcleral mass superonasal to the globe, adjacent to the superior rectus muscle insertion. The lesion was locally excised. A sarcoma could not be excluded on frozen sections. Permanent sections and electron microscopy revealed nodular fasciitis, a benign lesion with a pseudosarcomatous histologic appearance. No recurrence has been noted at 9 months follow-up. Nodular fasciitis is a benign proliferation which should be considered in the differential diagnosis of a rapidly enlarging subconjunctival or orbital mass in a child.
J Pediatr Ophthalmol Strabismus
PMID:Nodular fasciitis presenting as a rapidly enlarging episcleral mass in a 3-year-old. 236 27

A 7-week-old infant with sudden onset adduction deficit and proptosis is reported. The main differential diagnoses included orbital myositis, orbital cellulitis, capillary haemangioma and rhabdomyosarcoma. A CT scan revealed a postseptal cellulitis-like picture with thickening of the medial rectus muscle. He was given a course of antibiotics, withholding steroids and biopsy. His condition resolved completely on high-dose antibiotics alone. To our knowledge this is the youngest patient with infectious orbital myositis and postseptal cellulitis described in the literature. The clinical course emphasizes the importance of administering sufficiently high doses of antibiotics.
Strabismus 2002 Dec
PMID:Acute adduction deficit in a 7-week-old infant. 1266 Aug 49

The authors describe a case of orbital rhabdomyosarcoma masquerading as a lacrimal mucocele in a newborn infant. Rhabdomyosarcoma is one of the few life-threatening diseases that an ophthalmologist may be the first to diagnose. This case highlights the importance of close monitoring of such presentations in the newborn.
J Pediatr Ophthalmol Strabismus
PMID:Orbital rhabdomyosarcoma masquerading as a mucocele. 1882 4

An advanced case of rhabdomyosarcoma of the upper eyelid is used to demonstrate and discuss the principles of diagnosis and proper management of this most malignant extra-ocular neoplasm in the orbital region.
J Pediatr Ophthalmol Strabismus
PMID:The management of advanced rhabdomyosarcoma of the upper eyelid. 2487 54