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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An unfavorable outcome occurs in 31% of cases of treated severe threshold retinopathy of prematurity (ROP) and includes a retinal detachment of the posterior pole. Early treatment with laser of high risk prethreshold or type 1 ROP has significantly reduced this complication. However, despite prompt laser treatment, retinal detachments continue to be seen. Treatment of tractional partial retinal detachments involving the posterior pole (stage 4B ROP) is surgical. Successful reattachment of stage 4B ROP with a lens-sparing vitrectomy is high. The authors describe an infant who had spontaneous reattachment after stage 4B ROP.
J Pediatr Ophthalmol Strabismus
PMID:Spontaneous resolution of stage 4B retinopathy of prematurity. 1949 2

The authors present the first reported case of retinopathy of prematurity in twin-twin transfusion syndrome. A 31-year-old woman gave birth to twins at 31 weeks' gestation. The pregnancy had been complicated by twin-twin transfusion syndrome and had been managed with two amnioreductions and laser ablation of the interplacental blood vessels. The donor twin, born at 1,310 g, had threshold retinopathy of prematurity and underwent argon laser retinal photocoagulation treatment. The recipient twin (1,775 g) did not show any evidence of retinopathy of prematurity.
J Pediatr Ophthalmol Strabismus
PMID:Retinopathy of prematurity in twin-twin transfusion syndrome. 1964 2

Leukocoria in infants is always a danger signal as retinoblastoma, a malignant retinal tumor, is responsible for half of the cases in this age group. More common signs should also be considered suspicious until proved otherwise, such as strabismus, the second most frequent sign of retinoblastoma. Less frequent manifestations are inflammatory conditions resistant to treatment, hypopyon, orbital cellulitis, hyphema or heterochromia. Other causal pathologies, including persistent hyperplastic primary vitreous (PHPV), Coats' disease, ocular toxocariasis or retinopathy of prematurity, may also manifest the same warning signs and require specialized differential diagnosis. Members of the immediate family circle are most likely to notice the first signs, the general practitioner, pediatrician or general ophthalmologist the first to be consulted. On their attitude will depend the final outcome of this vision and life-threatening disease. Early diagnosis is vital.
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PMID:Differential diagnosis of leukocoria and strabismus, first presenting signs of retinoblastoma. 1966 20

Retinopathy of prematurity is a vasoproliferative disease that occurs mostly in premature and low birth weight neonates. It is a potentially blinding disease that should be screened vigorously. On the other hand, shaken baby syndrome is a non-accidental trauma that is both common and avoidable. Ophthalmologists play a crucial role in diagnosing and treating the shaken infant. The authors describe a child with the combination of retinopathy of prematurity and shaken baby syndrome.
J Pediatr Ophthalmol Strabismus 2009 Nov 02
PMID:Retinopathy of Prematurity and Shaken Baby Syndrome. 1987 54

Low birth weight infants are at greater risk of ophthalmic morbidity compared to children born at term. There are numerous studies detailing the outcome of low birth weight infants and the purpose of this paper is to discuss and summarize these studies, focusing on the long term effects on visual function and the prevalence of strabismus. The variation in study design will be discussed with regard to the subsequent effect on results. Despite the significant variation between studies, they all report an increase in the prevalence of strabismus and reduced visual acuity. This increase in ophthalmic morbidity is due in part to retinopathy of prematurity (ROP), but not all ophthalmic morbidity can be attributed to ROP.
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PMID:The long term ophthalmic morbidity of low birth weight children: a review. 2114 46

Trial of intravitreal bevacizumab injection in 7 eyes of 4 infants with continued retinopathy of prematurity progression despite previous laser therapy was reported. Six of the eyes benefited from the therapy. Intravitreal bevacizumab injection may be an alternative therapy in progressive stage 3 retinopathy of prematurity despite laser photocoagulation.
J Pediatr Ophthalmol Strabismus 2010 Aug 23
PMID:Intravitreal bevacizumab following laser therapy for severe retinopathy of prematurity. 2115 71

Posterior retinopathy of prematurity (ROP) is unusual in its atypical features and its aggressive, rapidly progressive course. It is more difficult to recognize and to treat, with many of these eyes progressing to retinal detachment despite multiple treatments with laser or cryotherapy. The authors present a case of aggressive posterior ROP refractory to multiple laser treatment. This patient was successfully treated with intravitreal bevacizumab, but required repeat treatment 4 months later. The second injection with bevacizumab was followed by progression to retinal detachment requiring surgery. The patient remains stable after surgery.
J Pediatr Ophthalmol Strabismus 2010 Dec 22
PMID:Retinal detachment despite aggressive management of aggressive posterior retinopathy of prematurity. 2117 13

In addition to refractive errors such as myopia and astigmatism, ocular disorders that occur in infants, toddlers, and children may present lifelong problems for the child. Conditions such as strabismus, amblyopia, and retinopathy of prematurity may require adaptations in adulthood. In addition, vision disorders that occur in childhood may manifest as problems well into adulthood. When visual impairment is present, there may be further effects on overall health, self-perception, educational attainment, job choices, and a number of other social factors.
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PMID:The impact of pediatric vision disorders in adulthood. 2119 55

The authors report zone III stage 3 retinopathy of prematurity requiring treatment in a former 1,692-g 30 6/7-week twin cared for in a modern intensive care nursery. This case highlights the need for identifying biomarkers that increase the risk of severe retinopathy of prematurity so that screening guidelines can be optimized.
J Pediatr Ophthalmol Strabismus 2010 May 21
PMID:Severe zone III retinopathy of prematurity in an infant with a birth weight of more than 1,500 grams. 2121 44

Retinopathy of prematurity is an emerging cause of blindness in Latin America. In 2007, the authors examined 88 consecutive infants in Guatemala City, Guatemala, who met the screening criteria for retinopathy of prematurity; 14 (16%) had either "plus" or stage V disease. The incidence of retinopathy of prematurity in Guatemala City is likely high, and a formal screening program is warranted.
J Pediatr Ophthalmol Strabismus 2010 May 21
PMID:The emergence of retinopathy of prematurity in Guatemala. 2121 59


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