Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The case of a one-year-old Nigerian with tuberculous panophthalmitis is reported. He presented initially with a localised episceleral mass which was thought to be retinoblastoma due to rapid spread over the fundus induced by subconjunctival depromedrol. Histological examination of the enucleated eye showed that the lesion was due to tuberculosis. The subsequent favorable response of the ocular and radiological chest lesions to antituberculous therapy was quite remarkable. In contrast, there was an adverse response to radiotherapy which had followed enucleation on the strong suspicion of retinoblastoma. Not unnaturally, ocular tuberculosis was not thought of because of the rarity of ocular involvement with this disease. To our knowledge, this is the first case of its type reported from the African Continent.
J Pediatr Ophthalmol Strabismus
PMID:Tuberculous panophthalmitis. 73 70

This report describes ocular injuries caused by syringes in children. The records of 12 children injured with syringes were reviewed. There were seven cases of endophthalmitis, two cases of panophthalmitis, one case of retinal detachment, one case of endophthalmitis with retinal detachment, and one case of traumatic cataract. All patients received treatment within 24 hours of presentation. Patients presented an average of 8.4 days after injury. Final visual acuity ranged from no light perception to counting fingers at 90 cm in eight patients and could not be assessed in four patients. Improperly disposed syringes may pose a significant risk for ocular injury and visual loss in children, especially when presentation is delayed.
J Pediatr Ophthalmol Strabismus
PMID:Severe ocular injuries from improperly disposed medical syringes in children. 2034 5