Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In early summer, 1990, 3590 schoolboys from the Al-Baha region of Saudi Arabia were assessed for their ocular status. Children from 15 schools were randomly selected to assess eye problems and visual defects. Of the boys examined 3521 (89.7%) had visual acuity of 20/30 or better and 3443 (95.9%) achieved 20/30 or better after correction. The main causes of visual impairment were refractive error in 260 (7.2%) and amblyopia in 58 (1.6%). Seventeen (0.5%) boys had strabismus. Vernal keratoconjunctivitis was found in 204 (5.7%). Four hundred and forty-nine (26.4%) had nonspecific conjunctivitis, 173 (4.8%) had bacterial conjunctivitis, and 28 (0.8%) had blepharitis. Of the five geographical areas surveyed, trachoma was only found in the Aqeek area among 49 (1.4%) schoolboys. Earlier detection and treatment of visual impairment is of paramount importance in decreasing the rate of visual loss among schoolchildren.
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PMID:Prevalence of ocular disorders among schoolboys in five villages in Al-Baha region. 1758 23

Vernal keratoconjunctivitis (VKC) is a severe chronic bilateral inflammation of the ocular surface characterized by seasonal exacerbations. Long-term prognosis is generally good; however, 6% develop sequelae responsible for permanent visual impairment. Corneal involvement is almost always present, consisting of punctate keratitis, shield ulcers (3-11%) and late corneal neovascularization. In recent years, topical cyclosporine A preparations at 2% in oil or at 1% in polyvinyl alcohol, have been successfully proposed for long term VKC treatments. It has been previously proven that medical treatment is not always sufficient, especially when it is employed to treat shield ulcer plaques. In such conditions, surgery may be effective for avoiding long term complications such as amblyopia, strabismus, infections and corneal perforation. In this paper, we show the efficacy of surgical debridement by means of simple scraping associated with topical cyclosporine treatment for the management of vernal shield ulcers complicated with plaques.
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PMID:Surgical debridement plus topical cyclosporine A in the treatment of vernal shield ulcers. 2305 30