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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We describe a young patient with combined hamartoma of the retina and retinal pigment epithelium who developed bilateral acoustic neuromas and meningiomas of the cervical-medullary junction and fifth cranial nerve. This case illustrates the association between combined hamartoma of the retina and retinal pigment epithelium and neurofibromatosis type 2. The authors recommend that children with a combined hamartoma of the retina and retinal pigment epithelium be screened for neurofibromatosis type 2.
J Pediatr Ophthalmol Strabismus
PMID:Combined hamartoma of the retina and retinal pigment epithelium in a patient with neurofibromatosis type 2. 175 56

A 2-year-old healthy white boy had a vitreous hemorrhage in the left eye but no history or external signs of trauma. Computed tomographic and ultrasonographic examinations were not diagnostic. A pars plana vitrectomy performed when the patient was 2 1/2 years old revealed a posterior pole lesion diagnosed clinically as a combined retinal-retina pigment epithelial hamartoma. Such lesions may be symptomatic because of decreased vision, macular puckering, and strabismus; vitreous hemorrhage has not previously been reported as the presenting clinical sign or the predominant cause for reduced vision.
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PMID:Combined retinal-retina pigment epithelial hamartoma presenting as a vitreous hemorrhage. 672 62

A pale, elevated peripapillary lesion discovered in a young child with no family history of phakomatoses, grew larger, caused vitreous hemorrhage and underwent necrosis. Secondary inflammation developed in the eye, finally producing rubeosis irides with elevated intraocular pressure and a blind, painful eye which required enucleation. Clinically, the lesion was variably diagnosed and treated as toxoplasmosis and toxocara canis. These diagnoses were made despite low titres, a negative ELISA test and a normal eosinophil count. On histopathologic examination, a diagnosis of toxocara canis was entertained, although no remnants of the organism could be found in serial sections. Years later, when a family history of tuberous sclerosis became apparent, a diagnosis of astrocytic hamartoma of the retina with secondary hemorrhage and inflammation was made on the basis of re-examination of the pathologic specimen and special stains.
J Pediatr Ophthalmol Strabismus
PMID:Astrocytic hamartoma in tuberous sclerosis mimicking necrotizing retinochoroiditis. 715 23

Multiple hamartoma and neoplasia syndrome, or Cowden's disease, is a genodermatosis inherited as an autosomal dominant trait with variable expressivity. We describe a woman with classic mucocutaneous features of the syndrome: facial papules, acral keratoses, oral mucosal papillomatosis, oral polyps and scrotal tongue. As a child she had strabismus. Her family history is positive for the disease, and a sister died of malignant melanoma. The check-up revealed chronic lymphocytic thyroiditis. A checklist for use in screening patients with Cowden's disease is proposed.
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PMID:[Cowden's syndrome]. 767 86

Combined hamartoma of the retina and retinal pigment epithelium is a rare, congenital fundus lesion which typically presents with a history of reduced acuity and/or the onset of strabismus. Clinically, the lesion is elevated, with a variably pigmented outer portion and a lighter central core of dilated tortuous vessels and gliosis. This benign lesion may be confused with more threatening conditions such as malignant melanoma or retinoblastoma. An appropriate diagnosis through clinical appearance and fluorescein angiography is imperative to prevent unnecessary enucleation. The authors report one case of combined hamartoma of the retina and retinal pigment epithelium in a patient presenting with a complaint of decreased vision.
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PMID:Combined hamartoma of the retina and retinal pigment epithelium. 824 91

We report a 13-year-old male who complained of strabismus and low visual acuity in the right eye. Saccular aneurysms filled with dark-colored blood were noted in the upper nasal quadrant of the right fundus. Ishihara color plates and Lanthony's new color test revealed a red-green color defect. Cone response and 30-Hz flicker responses were nearly absent. Cavernous hemangioma of the retina is a rare vascular hamartoma; the associated findings show cone dysfunction concomitant with this peripheral lesion.
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PMID:Cavernous hemangioma with cone dysfunction. 888 97

The retinal pigment epithelium and retinal hamartoma is a rare benign tumor. We describe a case of combined hamartoma of the pigment epithelium and retina in an eight year-old-girl with strabismus and amblyopia. The fluoresceinic angiography and the echography allowed to exclude a malignant tumor of the retina or the choroid. The clinical follow-up confirmed that the lesion was stationary. History, pathogeny, differential diagnostics and treatment are discussed.
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PMID:[Hamartoma of the pigment epithelium and retina. Apropos of a case]. 918 Nov 42

We describe a 15-year-old girl with congenital simple hamartoma of the retinal pigment epithelium associated with congenital retinal arterial macrovessel crossing the macular region. To our knowledge, there are no reports of this association.
J Pediatr Ophthalmol Strabismus
PMID:Congenital retinal arterial macrovessel and congenital hamartoma of the retinal pigment epithelium. 1676 43

A 7-month-old infant was examined for severe right ptosis, strabismus, and noisy breathing. CT revealed a right intranasal mass with areas of calcification, erosion, and extension to the cribriform plate. Surgical resection was performed. Pathologic examination confirmed the diagnosis of nasal chondromesenchymal hamartoma. Ophthalmologists may be among the first medical practitioners to encounter nasal chondromesenchymal hamartoma, a rare, benign neoplasm of the nasal and paranasal sinuses.
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PMID:Ophthalmologic presentation of nasal chondromesenchymal hamartoma in an infant. 1751 72

A 31-year-old pregnant woman presented with subacute painful proptosis due to an orbital apex mass arising from the right medial rectus muscle. The patient developed compressive optic neuropathy refractory to systemic prednisone and underwent orbitotomy with posterior orbital decompression through a transcaruncular approach. Pathologic examination showed intramuscular hemangioma, a benign vascular hamartoma of skeletal muscle, which rarely occurs in the orbit. The optic neuropathy and proptosis resolved without consecutive strabismus or enophthalmos.
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PMID:Orbital intramuscular hemangioma enlarging during pregnancy. 1993 59


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