Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In this study, the authors present a homogeneous series of seven children suffering from persistent hyperplastic primary vitreous, in its complete anterior and posterior form. These children were operated by pars plana lensectomy and vitrectomy. The surgical operation was beneficial in every case: not only were there no complications, but the operation also prevented progression towards neovascular glaucoma, vitreous hemorrhages and phtisis bulbi. In addition, one of the benefits of this technique was esthetic, with the disappearance of leucocoria, the occasional correction of strabismus and the reduction in microphthalmos. Visual recovery can be surprisingly good, in the absence of any associated retinal malformation.
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PMID:[Persistent hyperplastic primary vitreous. Middle-term results of vitrectomy]. 143 Aug 2

Retinal vasoproliferative tumor is an uncommon benign vascular tumor that most often occurs sporadically. Vision loss can occur secondary to retinal fibrosis, subretinal exudation, and neovascular glaucoma. This report describes a functionally monocular patient with neurofibromatosis type 1 who had a vasoproliferative tumor with neovascularization of the iris that was successfully treated with intravitreal bevacizumab and cryotherapy.
J Pediatr Ophthalmol Strabismus 2009 Jun 25
PMID:Retinal Vasoproliferative Tumor in Association with Neurofibromatosis Type 1. 1964 88

This report describes an extremely rare case of Coats' disease and neovascular glaucoma in a child with neurofibromatosis 1. Intraocular pressure control and vision restoration were achieved with intravitreal injection with bevacizumab, hemiretinal laser photocoagulation, peripheral retinal cryotherapy, and trabeculectomy with mitomycin C.
J Pediatr Ophthalmol Strabismus 2011
PMID:Coats' disease and neovascular glaucoma in a child with neurofibromatosis. 2021 Feb 81

A 6-year-old boy presented with neovascular glaucoma secondary to total retinal detachment. Magnetic resonance imaging findings suggested diffuse infiltrating retinoblastoma. Enucleation was subsequently performed and led to a final histopathological diagnosis of advanced Coats' disease. Diffuse infiltrating retinoblastoma and advanced Coats' disease can be indistinguishable from each other on magnetic resonance imaging.
J Pediatr Ophthalmol Strabismus 2010 Aug 23
PMID:A magnetic resonance imaging diagnostic dilemma: diffuse infiltrating retinoblastoma versus Coats' disease. 2115 70

A 12-year-old girl with neurofibromatosis type 1 was referred for pain and blurred vision in her right eye for the past 2 weeks. Neovascular glaucoma associated with peripheral retinal ischemia was diagnosed and she was treated with retinal photocoagulation after intravitreal bevacizumab injection and trabeculectomy.
J Pediatr Ophthalmol Strabismus 2010 May 21
PMID:Unusual association of peripheral retinal ischemia-induced neovascular glaucoma and neurofibromatosis type 1. 2121 63

Five case histories are presented. Waldenstrom's macroglobulinaemia caused bilateral central retinal vein occlusion, proptosis was the presenting feature of retro-orbital plasmacytoma in relapsed multiple myeloma, a red painful eye was due to neovascular glaucoma in primary polycythaemia, bilateral VIth nerve palsy caused convergent squint and diplopia in meningeal relapse of acute lymphoblastic leukaemia and lymphoma of the eyelid caused complete ptosis. Interdisciplinary management is described. Ophthalmological lesions in haematological disease should be promptly recognized and managed. Collaboration between ophthalmology and haematology departments may be effective for palliative management.
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PMID:Ophthalmic manifestations of haematological disorders. 2417 39

We present a case of a 9 years old boy, followed up for 4 years, with bilateral combined pigmented epithelial and retinal hamartoma, complicated with recurrent vitreous hemorrhages in one eye and neovascular glaucoma and cataract in the other eye, treated with repeated intravitreal injections of Bevacizumab. A review of the literature suggested that such lesions may be symptomatic because of decreased vision, macular pucker, strabismus and vitreous hemorrhages. This particular compressive, bilateral form of hamartoma of the optic nerve has not previously been reported as a cause for such an ischemic syndrome, complicated with neovascular glaucoma and cataract.
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PMID:Complications of combined retinal and retinal pigment epithelium hamartoma involving the optic disc in a child, treated with Avastin - a review of the literature and case presentation. 2945 Mar 17