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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Succinylcholine was injected intraoperatively in 41 strabismus patients with congenital esotropia or intermittent or constant exotropia. Regression analyses were performed to investigate the predictive relationships between the one-, six-, and 26-week postoperative alignment and the intraoperative, succinylcholine-induced ocular position. Ocular position, determined by the interlimbal distance in millimeters, was calculated using a semi-automated, video replay analysis system. Large, statistically significant correlation coefficients were obtained for patients undergoing bimedial recessions of 4.0 to 5.5 mm and bilateral lateral rectus recessions of 5.0 to 7.0 mm. Small correlations were obtained for esotropes undergoing the recession/resection procedure and those with bimedial recessions of 6.0 mm or greater. These data support the theory that the succinylcholine-sensitive subgroup of the extraocular muscle fibers are those whose tonic contracture provide the motor component to ocular alignment. Sample sizes at present are insufficient to suggest clinical use of these data. In future research, these relationships will be tested for their ability to predict postoperative alignment and thereby, improve success rates in strabismus surgery.
J Pediatr Ophthalmol Strabismus
PMID:A comparison of the succinylcholine induced ocular position and the postoperative alignment in strabismus. 395 73

This paper reports nine patients who developed accommodative esotropia following correction of intermittent exotropia. Eight cases originally were esotropic; one was esotropic secondary to previous surgery for nonaccommodative esotropia. All had the pattern of "divergence excess." In seven patients recession of both lateral recti had been performed in conventional amounts; one case had a recession/resection procedure, and one case recession of the lateral recti followed by resection of the medial recti. In all cases the consecutive accommodative esotropia included an abnormally high distance/near relationship. All were controlled by appropriate optical or drug treatment, and six cases deteriorated later. Surgical overcorrection was not a prominent contributing factor. Preoperative occlusion and/or the +3.00 D test would not have predicted the persistence of the high distance/near relationship. There were no other obvious indicators of this complication.
J Pediatr Ophthalmol Strabismus
PMID:Consecutive accommodative esotropia. 398 40

A 20-year old female was found to have an alternating pattern of right esotropia and right exotropia following surgery for a clivus chordoma three years previously. When esotropic, abduction was markedly limited while adduction was full in the right eye. When exotropic, mild limitation of both abduction and adduction was noted. Horizontal saccadic velocity studies were consistent with the diagnosis of sixth nerve palsy when esotropia was manifest and a Duane's syndrome, type II when exotropia was present. The etiology of these unusual findings is not well understood.
J Pediatr Ophthalmol Strabismus
PMID:Varying esotropia-exotropia. 399 77

Strabismus was present in 40% of patients with cataracts/dislocated lenses at the time of initial diagnosis and continued to present an obstacle to complete rehabilitation with 86% of the congenital patients and 61% of the acquired patients found to have strabismus at their latest post therapy visits. The type of horizontal deviation found at the initial examinations was distributed equally between esotropia and exotropia in the unilateral congenital cataracts patients. However, all of our patients with strabismus and bilateral congenital cataracts were esotropic. The acquired group was heavily weighted toward the exodeviations at the time of the initial examination and during treatment showed an even greater percentage of exotropia. Visual acuity results in the various groups followed perhaps the expected trends with the poorest results in the unilateral congenital cataract patients. Those patients in the acquired groups have better visual results with 56% of the traumatic and 83% of the non-traumatic eyes achieving vision of 20/70 or better. Despite the high incidence of strabismus present in these patients, we feel this should in no way be a deterent to the decision to initiate therapy as it does not seem to relate to visual acuity results. The overall good visual results in these patients justifies the approach of early surgery, adequate correction, and vigorous occlusion.
J Pediatr Ophthalmol Strabismus
PMID:The association of strabismus and aphakia in children. 633 54

In order to isolate some of the factors responsible for strabismic amblyopia as well as to ascertain the time course of its development, frequent measurements were made of the visual acuity of the two eyes of kittens following imposition of surgically induced strabismus. Following behavioural training on a jumping stand, strabismus was induced in all but one animal by simple section of either the lateral (esotropia) or medial (exotropia) rectus muscle of one eye. The one exception was a kitten on which esotropia was induced by another common but more radical surgical procedure that involved removal of the body of both the lateral rectus and superior oblique muscles of one eye. There was a surprising difference between the immediate consequences for vision of section of the lateral and medial rectus muscles that were reflected by equally large differences in the magnitude of the amblyopia that developed eventually in the two situations. Following section of the lateral rectus muscle, there was an immediate reduction in the visual acuity of the operated eye of as much as 2 octaves after which vision returned to normal levels over 4 to 8 days. The acuity of the two eyes remained comparable for a few days after which the vision of the operated eye began to decline once more, signalling the onset of amblyopia some 10 to 12 days following imposition of strabismus. In contrast to the severity of these effects, the effects observed following section of the medial rectus were both mild and transitory. Furthermore, whereas all kittens that were rendered esotropic early developed amblyopia, none of the kittens that were made exotropic at the same age did so. Together, these results suggest that factors associated with the immediate consequences of the surgical procedure employed to produce a misalignment of the visual axes may contribute to the severity of the effects of surgically induced strabismus.
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PMID:Immediate and long-term effects on visual acuity of surgically induced strabismus in kittens. 646 49

Recordings were made from striate cortex in five groups of cats that had been raised with strabismus produced by sectioning the extraocular muscles. These groups included animals reared with exotropia, unilateral or bilateral esotropia, and esotropia combined with lid suture of the unoperated eye. In addition, a group of esotropes was studied in which the unoperated eye was removed a few hours prior to recording. For comparison, five normal adult cats were also studied. In each of the above groups, cells were sampled in the representations of the central and peripheral visual fields in area 17 ipsilateral and contralateral to the deviated eye. We mapped the receptive field of each responsive cell, determined its ocularity, and tested it for selectivity. Confirming previous work, we found a marked loss of cortical binocularity in cats raised with strabismus. On average only 7% of the neurons that we recorded could be driven by both eyes. This percentage was relatively constant at all cortical locations that were studied and was not influenced by whether cats had been reared with exotropia, unilateral esotropia, or bilateral esotropia. The percentage of selective cells driven by the deviated eye in exotropes or esotropes did not appear to be different from normal at most cortical locations (but see 5, below). In addition, we did not observe any bias in the axial preference of selective cells in strabismic cats when compared with normal adult cats. In both exotropes and esotropes the deviated eye drove fewer cells when compared with the proportion that are driven by one eye in normal cats. In exotropes this deficit did not vary at different cortical representations of the visual field. In esotropes, however, this deficit was graded, being least in the representation of the peripheral visual field in area 17 contralateral to the deviated eye, intermediate in the representations of the central visual field in the contralateral and ipsilateral hemispheres, and greatest in the representation of the peripheral visual field in ipsilateral area 17. Furthermore, only when recording from the peripheral field representation in the ipsilateral hemisphere did we encounter significant numbers of cells driven by the deviated eye that lacked normal selectivity. Since it is possible that deprivation of the converged eye during development might account for the deficits noted above, we attempted to evaluate this factor using several independent lines of evidence. First, we could find no correlation between the angle of esotropia and the ability of the deviated eye to drive ipsilateral cortical cells representing the peripheral visual field.(ABSTRACT TRUNCATED AT 400 WORDS)
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PMID:Response properties of striate cortex neurons in cats raised with divergent or convergent strabismus. 648 42

A 34-year-old Caucasian woman underwent craniofacial surgery for fronto-orbital fibrous dysplasia. She developed vertical diplopia for 10 months after surgery, which then disappeared for 1 month. The deviation returned with a circadian pattern, 24 hours of hypertropia and exotropia with diplopia alternating with 24 hours of straight eyes and fusion. Three months after the onset of this pattern, surgery was performed, resulting in straight eye position and fusion daily. The similarities to cyclic esotropia are discussed. The etiology of circadian strabismus remains unknown.
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PMID:Cyclic vertical deviation. 653 21

Twenty-nine patients have undergone major subtotal orbital translocation surgery between 1976 and 1980. Extra-ocular muscle function has been studied before and after orbital surgery. Medial orbital translocation, like sagittal orbital translocation, produces a decrease of exotropia; sometimes there is no change which proves the importance of well-established binocular vision. Orbital osteotomy in the three planes can produce a modification of the primary position of a vertical imbalance but it has no action on the vertical movements. The ophthalmologist can predict the post-operative result when he knows what type of ocular abnormality exists and what type of orbital surgery will be performed. He can also discuss the timing of strabismus surgery.
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PMID:Change in eye position after cranio-facial surgery. 658 54

We examined cortical responses evoked by 8-Hz, phase-shifted sine wave gratings at a range of contrasts and spatial frequencies in normal cats and in cats raised with artificial esotropia or exotropia. There were no significant differences between the amplitudes of the responses evoked through the two eyes of the normal cats, but for some esotropes and exotropes the responses evoked through the unoperated eye were larger than those evoked through the operated eye. Interocular response differences were comparable in all affected cats and were most pronounced at high contrasts. These results indicate that rearing with artificial strabismus can produce amblyopia in both esotropes and exotropes, and that the amblyopia is similar in the two cases.
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PMID:Visual-evoked responses from strabismic cats. A comparison of esotropes with exotropes. 661 98

Campos (1982a) reported on his psychophysical studies on the binocularity of patients with comitant strabismus. With binocular visual field techniques, it was possible to show that patients with small-angle eso- and exotropia exhibit a binocular vision, without suppression of the deviated eye. In the present paper visual electrophysiology is used objectively these findings and to provide more insight in the problem. First, the studies on binocularity in normals and strabismics, done by using visual evoked responses (VER) are reviewed. This type of investigation is relatively new and the results of the literature are still conflicting. Then personal results of the authors are reported. It is shown that with VER it is possible to objectively assess the presence of anomalous binocular vision (ABV) sustained by anomalous retinal correspondence (ARC) in small-angle strabismus. In patients with large angle deviations this type of binocularity is absent. A correlation between psychophysical and electrophysiological data is provided. Lastly a simple method is described for differentiating the binocularity of normals from that of Strabismics with ARC. This method is based on the recording of binocular VER with the anteposition in front of the fixing eye of neutral filters of increasing density.
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PMID:Binocularity in comitant strabismus: II. Objective evaluation with visual evoked responses. 664 76


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