Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An eight-month-old girl presented with congenital exotropia and latent nystagmus. Further evaluation revealed congenital ptosis of the left eye and restriction of the elevation, depression and adduction of the left eye. A diagnosis of congenital oculomotor palsy was made. At the age of three months she had been examined by the neurologist because of retarded psychomotor development. All laboratory investigations were normal. At the age of eight months, a CT scan of the brain and orbit was found to be normal. The patient was treated for amblyopia. At the age of five, strabismus surgery was performed, and a large fibrous tumor encapsulating the superior and lateral rectus muscle was found. A biopsy was taken and pathology showed fibrous tissue containing a hair. Based on the clinical history, the diagnosis of a perinatally ruptured orbital dermoid cyst was made. Review of the previous CT and an additional CT showed enlargement of the left lateral orbital wall with a notch in the lateral wall, indicative of a dermoid cyst.
Strabismus 2000 Mar
PMID:Perinatally ruptured dermoid cyst presenting as congenital oculomotor palsy. 1085 51

This report describes a case of orbital dermoid cyst presenting with a discharging sinus tract. The embryologic basis for orbital dermoids in general is discussed, as well as their typical presentation and management. In the current case, patient presentation and management were somewhat different because of signs of infection and a communicating sinus tract, both highly unusual for orbital dermoids. However, after complete excision of the dermoid and sinus tract, the patient showed complete recovery.
J Pediatr Ophthalmol Strabismus 2009 Jun 25
PMID:Orbital Dermoid Cyst Presenting with a Discharging Sinus Tract. 1964 75

A 24-year-old male presented with decreased vision associated with inward deviation of his left eye since childhood and gradually progressive prominence of left eye for 6 months. Left eye examination revealed visual acuity of 2/60, convergent squint with restricted abduction and medial dystopia. Computed tomography (CT) scan showed a well-circumscribed mass with fat fluid levels temporal to the optic nerve indistinguishable from the left lateral rectus. Intraoperatively, a well-encapsulated mass was identified within the lateral rectus muscle which was confirmed as dermoid cyst on histopathology. Patient subsequently underwent surgical correction of his esotropia and the final cosmetic outcome was satisfactory. Dermoid cysts are common orbital lesions usually found overlying suture lines. A dermoid cyst presenting within the ocular muscles is a rare entity. Deep dermoid cyst should be considered as one of the differentials for focal enlargement of extraocular muscles.
 ...
PMID:Lateral rectus dermoid cyst presenting as incomitant esotropia. 3069 58

The authors report the case of a 6-year-old boy who presented to their outpatient department with complaints of progressively increasing swelling on the left upper eyelid since birth. The swelling was excised and was found to be firmly attached to the tarsus. Histopatho-logical examination reported a cyst lined by stratified squamous epithelium with presence of adnexal structures in the subepithelium. Therefore, the diagnosis of tarsal dermoid cyst was made. [J Pediatr Ophthalmol Strabismus. 2020;57:e41-e42.].
J Pediatr Ophthalmol Strabismus 2020 Jun 23
PMID:An Unusual Presentation of a Dermoid Cyst Mimicking a Chalazion. 3257 86