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Query: UMLS:C0038379 (strabismus)
 9,317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Shigella keratitis with ulceration is a rare occurrence with only four previous reports in the literature. Corneal ulceration appears to be characteristically superficial with a predilection for the inferior cornea. In the case reported here, resolution of ulceration occurred with the use of gentamicin and chloramphenicol, following a poor response to sulfacetamide. Experimental evidence strongly suggests that the course of infection is usually self-limited but that corneal scarring is a common sequelae. In the majority of the clinical cases reported to date, corneal ulceration has responded to appropriate antimicrobials with resolution, but has left residual opacification. To the extent that all of the cases were in young children, assessment of the degree of visual loss has been difficult to ascertain.
J Pediatr Ophthalmol Strabismus
PMID:Corneal ulceration due to Shigella flexneri. 698 65

Eye growth is regulated by a precise, sharp image of a distant object on the photoreceptor layer. A variety of laboratory investigations report that translucent occluders may induce axial eye elongation in animals. This axial growth is also called form deprivation myopia (FDM). In our pediatric ophthalmology clinic we observed the clinical correlate of FDM in a male infant with unilateral corneal ulcer due to a congenital tarsal malformation. Examination in the postnatal period under anesthesia revealed identical axial length in both eyes. Refraction of the affected eye could not be measured due to severe corneal ulcer. During an observation period of two years, the deep corneal opacification of the affected eye induced unilateral disproportionate axial elongation with formation of myopia. Formation of FDM may complicate treatment of amblyopia following unilateral media opacification. Periodic measurements of refraction should be performed to allow appropriate correction.
Strabismus 2002 Jun
PMID:Formation of a unilateral form deprivation myopia (FDM) due to a congenital eyelid entropium with a consecutive corneal ulcer: an illustrated case report. 1222 88

The recognition of ocular manifestations in juvenile idiopathic arthritis is critical. The authors report an unusual manifestation of corneal involvement in a 10-year-old girl with systemic-onset juvenile idiopathic arthritis who presented with unilateral peripheral ulcerative keratitis during arthritis exacerbation. Corneal inflammation was successfully managed with topical steroids, oral methylprednisolone, and methotrexate.
J Pediatr Ophthalmol Strabismus 2010 Oct 21
PMID:Peripheral ulcerative keratitis in a patient with systemic-onset juvenile idiopathic arthritis. 2116 64