Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038362 (stomatitis)
 8,852 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Twenty-eight out of 30 patients suffering from denture-wearer's stomatitis, yielded yeast-like fungi from the areas of inflammation. The fungi included Candida albicans (20), Torulopsis glabrata (7), C. tropicalis (3), C. pseudotropicalis (1), and C. krusei (1). In 15 cases, a heavy fungal growth was found. Of the 20 C. albicans strains, 18 exhibited an extra-cellular proteolytic activity on Serum-Albumin agar with the initial pH value of 5.0. In the sera from 20 patients, precipitating antibodies against C. albicans antigens were detected with the help of the immunodiffusion test. The haemagglutination test revealed titers greater than or equal to 1:160 in 18 cases. The questionable pathogenic significance of the yeast-like fungi in the denture wearer's stomatitis is discussed.
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PMID:[Mycological findings in denture stomatitis and their evaluation]. 675 24

Albumin concentrations were measured in whole and parotid saliva samples collected from patients who were undergoing various cancer treatment protocols and had a high incidence of stomatitis. Oral examinations were made at the time of saliva collection and the degree of stomatitis evaluated. Elevations of whole saliva albumin concentrations were observed in 11 stomatitis incidents. No increases were observed in parotid saliva. The salivary albumin increases always preceded and often occurred in the absence of stomatitis, suggesting that the whole saliva albumin level may be a useful measure and predictor of this condition. If so, monitoring of this parameter could be useful in establishing treatment schedules for chemotherapy protocols that have stomatitis as the limiting factor in treatment.
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PMID:Whole saliva albumin as an indicator of stomatitis in cancer therapy patients. 702 57

Denture stomatitis is an inflammatory condition affecting palatal mucosa covered by a denture. Aetiology is multifactorial involving poor hygiene, constant denture wearing, trauma and colonisation by Candida species. In inflamed tissues raised levels of albumin, IgG isotypes and secretory IgA (sIgA) would be expected. SIgA is a major component of the protective immunological response to mucosal injection. Palatal secretions of 21 patients with denture stomatitis and 22 denture wearing patients with clinically healthy palates were analysed for albumin, IgG isotypes and sIgA levels. Albumin and IgG isotype levels were found to be higher in denture stomatitis patients compared with healthy palate patients. Unexpectedly, SIgA levels were found to be significantly (p<0.05) lower in denture stomatitis patients compared with healthy palate patients.
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PMID:Comparison of secretory IgA and IgG isotype levels in palatal secretions of denture stomatitis patients with denture wearers having clinically healthy palates. 1764 64