Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038362 (stomatitis)
 8,852 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Poor feedlot performance in native Hawaiian feedlot cattle was investigated. Cattle were first noticed to be affected 40 to 60 days after arrival at the feedlot, as judged by their retarded growth, when compared with penmates. Marked hypocupremia was detected in all 10 cattle examined, irrespective of time in the feedlot. Clinical signs and upper digestive tract lesions in 8 of the 10 cattle suggested secondary involvement of bovine papular stomatitis. The poor performance was attributed primarily to the hypocupremia, as a result of molybdenum-accentuated copper deficiency in forage on the ranch of origin.
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PMID:Poor growth performance associated with hypocupremia in Hawaiian feedlot cattle. 42 61

In view of the fact that bis cyclopentadienyl metal dihalides are known to be anti-tumour drugs, we have investigated the antiviral activity of this type of coordination compounds. Bis cyclopentadienyl titanium dichloride (a) has shown significant antiviral efficiency in vitro against representatives of a nuber of enveloped DNA and RNA viruses. Inhibition of orthopoxvirus (vaccinia), herpes virus (pseudorabies), orthomyxoviruses (influenza A/fowl plague [FPV], influenza A/Victoria 3/75, influenza A/jena 48/78 and influenza B/Johannesburg), paramyxovirus (Newcastle disease [NDV]) and rhabdovirus (vesicular stomatitis [VSV]) was observed after direct contact with the compound under loss of infectivity up to 100%. Regarding the group of unenveloped viruses only adenovirus type 4 became influenced but not type 5. No antiviral activity could be found against the cardiovirus Mengo. The compound bis cyclopentadienyl molybdenum dichloride failed to show an antiviral action versus vaccinia, influenza A/FPV and influenza viruses B/Johannesburg. Application of the inhibitor (a) during the replication of vaccinia and influenza viruses A/FPV in cell cultures produced an additional effect of inhibition of virus multiplication. On the other hand, adenovirus type 4 and VSV replication was not affected by titanocene dichloride.
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PMID:[On the biological action of transition metal complexes. 4. The antiviral activity of metallocene dichlorides of titanium and molybdenum (author's transl)]. 627 97