Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038362 (stomatitis)
 8,852 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

It was the purpose of the study to test the efficacy of dissolvent tablets containing mutanase and protease in preventing formation of plaque on the fitting surface of complete dentures. The study group consisted of 60 denture wearers with denture stomatitis who were assigned randomly into an enzyme group, a placebo group, or a Steradent group. After denture treatment was completed the patients were instructed to immerse the new dentures for 15 min once daily for one month in the denture cleanser. The amount of denture plaque, the clinical condition of the palatal mucosa, and the concentration of yeasts in mucosal and denture smears were recorded while the patients used their original dentures and after the experimental period. The study was designed and carried out as a double-blind study. New denture plaque had formed in all patients; however in the enzyme group significantly reduced plaque scores were recorded as compared with the plaque scores recorded on the original dentures. The Steradent tablets or the placebo tablets had no apparent effect.
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PMID:Prevention of denture plaque formation by an enzyme denture cleanser. 12 96

It was the purpose of the study to test the efficiency of dextranase, mutanase, and protease in removing denture plaque. The study group comprised 100 denture-wearers with denture stomatitis. The enzymes were dispensed as dissolvent tablets either in pure or in mixed preparations. Placebo tablets and Steradent, a commercial denture cleanser, were used as control tablets. The following parameters were studied: the amount of denture plaque, the degree of palatal erythema, and the concentration of yeast cells and inflammatory cells in mucosal and denture smears. The study was designed and carried out as a double-blind study. The dissolvent tablets containing the enzymes in mixed preparations were more effective than the tablets containing the pure enzymes, the placebo tablets, or the Steradent tablets. The beneficial effect of the mixed enzyme preparations included a significant reduction of the amount of denture plaque and an improvement of the clinical condition of the palatal mucosa.
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PMID:Enzymes as denture cleansers. 32 51