Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038362 (stomatitis)
8,852 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Patients who are hypersensitive to mercury may develop stomatitis on mucosa adjacent to amalgam dental restorations. This reaction, an allergic contact dermatitis, often resembles lichen planus but is distinguished by its location adjacent to restorations. Widespread dermatitis and urticaria are also possible.
Dermatol Clin 1990 Jan
PMID:Stomatitis and systemic dermatitis from mercury in amalgam dental restorations. 230 56

The diagnosis of chronic granulomatous disease of childhood was made in a 10-year-old boy following episodes of recurrent cervical abscesses and ulcerative stomatitis since the age of 4 years. Nineteen years on, on antibiotic prophylaxis, he is now married and remains active although he has been hospitalized with serious complications on many occasions.
Clin Exp Dermatol 1989 Nov
PMID:Chronic granulomatous disease--a case showing long-term survival. 260 12

Denture sore mouth is most often caused by improperly fitting dentures. Ulcers, stomatitis, hyperplasia, bone resorption, and chronic candidiasis may develop under improperly fitting dentures. If extensive bone resorption occurs, dental implants may be necessary. Malignant changes can develop.
Dermatol Clin 1987 Oct
PMID:Denture sore mouth. 331 46

Allergic contact stomatitis may be difficult to distinguish from irritant stomatitis and may mimic the oral changes of a vitamin deficiency, certain anemias, uremic stomatitis, stomatitis nicotina, and even candidiasis. When these conditions have been ruled out, skin patch testing may be indicated. There is no need to test the oral mucosa directly because the oral mucosa and skin are sensitized at the same time.
Dermatol Clin 1987 Oct
PMID:Contact stomatitis. 331 49

Thirty-three patients with alcoholic cirrhosis (AC), selected on widely recognized criteria (16, 57), were investigated prospectively for cutaneous manifestations of zinc deficiency. The patients were divided into 3 groups: group A (n = 12): AC without skin lesions; group B (n = 12): AC with skin lesions responsive to a zinc-free topical treatment or resistant to enteral zinc sulfate intake; group C (n = 9): AC with skin lesions cured by oral zinc replacement therapy alone. The lesions observed in group C were studied microscopically. Data concerning zinc metabolism (Zn concentrations in plasma, red cells, urine and hair; alkaline phosphatase values), biochemical criteria of AC (plasma serum-albumin concentration, IgA/transferrin ratio) and a malabsorption test (xylosemia 120 min after oral absorption of D-xylose 25 g) were compared by the variance analysis method. A control group (D, n = 12) was used as reference. Few cases of cutaneous manifestations of zinc deficiency in AC patients have been published. In more than one half of the 15 or so we found in the literature, an aggravating factor (total parenteral nutrition, digestive tract surgery) had to be taken into account. In this prospective study 9 new cases in which AC was the only cause of zinc deficiency are reported. A clinical picture similar to acrodermatitis enteropathica with peribuccal bullous lesions was observed in only one patient. In all other cases the patients presented with a cracked and reticulated eczema on the extensor aspect of the limbs and (often erosive) in the perianal and genital regions. The eczema was associated with cheilitis, glossitis, stomatitis, alopecia and, seldom, ungual Beau's lines. Disorders of behaviour, diarrhoea and bouts of lever regressing under zinc replacement therapy were frequent. Histology was not very specific, except for the presence of necrotic areas in the stratum germinativum, sometimes associated with small subcorneal pustules containing altered polymorphonuclears. In every case, it was the rapid regression of symptoms under zinc sulfate treatment that confirmed the diagnosis. Plasma zinc concentrations were most significantly decreased in all AC groups as compared to controls (61.2 +/- 19.4 vs 97.8 +/- 10.4 micrograms/100 ml) and also in AC patients with skin manifestations of zinc deficiency as compared to the other AC patients (44.4 +/- 9.2 vs 66.5 +/- 18.8 micrograms/100 ml) table V). Changes in serum-albumin levels and in hepatocellular function were parallel to changes in plasma zinc concentrations.(ABSTRACT TRUNCATED AT 400 WORDS)
Ann Dermatol Venereol 1987
PMID:[Cutaneous manifestations of zinc deficiency in ethylic cirrhosis]. 357 31

The authors report a case of oral submucous fibrosis and present a review of the literature available on this subject. Oral submucous fibrosis is rare outside South-East Asia where it affects from 0.2 to 1 p. 100 of the population. A few cases have been described among Europeans. The disease seems to be specific to the oral and upper respiratory mucosae. It is characterized by the progressive development of subepithelial fibrosis and the subsequent occurrence of leukoplakia which may undergo transformation into epidermoid carcinoma. It initially presents as a non-specific stomatitis, sometimes with vesicles and ulcerations. Very gradually thereafter the buccal mucosa becomes pale in parts, as well as thicker and fibrous, while leukoplakia develops. These lesions progress slowly and may eventually result in complete and irreducible trismus. Histologically, oral submucous fibrosis is characterized by chronic subepithelial inflammatory reaction followed by hyalinization. Subsequently, the fibrosis extends to the underlying muscles. The epithelium is diversely affected: atrophy is thought to be the first lesion to appear; secondarily, and under the influence of various irritant factors, epithelial hyperplasia, ortho- or parakeratosis of the stratum corneum, or even cellular abnormalities may develop.(ABSTRACT TRUNCATED AT 250 WORDS)
Ann Dermatol Venereol 1986
PMID:[Oral submucous fibrosis. Review of the literature apropos of a case]. 371 61

Lichenoid stomatitis has been reported in the use of a number of drugs. This is a case report of lichenoid stomatitis associated with lithium carbonate. The association between lichenoid stomatitis and lithium carbonate was confirmed by rechallenge in this patient. A number of cutaneous reactions have been reported as adverse effects of lithium therapy. Lichenoid reactions are characterized by an infiltrate of T cells. Lithium has been reported to alter T cell function in vitro.
J Am Acad Dermatol 1985 Aug
PMID:Lichenoid stomatitis associated with lithium carbonate. 393 May 81

Inasmuch as orf, milker's nodules and bovine papular stomatitis pox are clinically identical in man and are induced by currently indistinguishable parapox viruses, we propose a new generic term 'farmyard pox' for these diseases. This affords the clinician a diagnosis based on a common set of clinical and electron microscopic findings rather than one based on an uncertain or even misleading history. A case in point is reported in which the history failed to reveal a specific animal source of the virus, but electron microscopy confirmed the presence of parapox infection.
Br J Dermatol 1983 Jun
PMID:Farmyard pox: parapox virus infection in man. 630 84

Increasing numbers of chemotherapeutic agents are being used to treat patients with cancer and various immunologically mediated and inflammatory disorders. Many of the drugs used have distinctive cutaneous side effects that range from relatively common ones, such as alopecia, stomatitis, and hyperpigmentation, to more unusual ones, such as radiation enhancement and recall phenomena, photosensitivity and hypersensitivity reactions, and phlebitis or chemical cellulitis. In addition, there are some rare complications such as diffuse sclerosis of the hands and feet, Raynaud's phenomenon, sterile folliculitis, and flushing reactions. By being aware of which drug may have caused a particular cutaneous reaction, dermatologists will be able to contribute to the care of patients with complex problems in a meaningful way.
J Am Acad Dermatol 1983 Nov
PMID:Cutaneous complications of chemotherapeutic agents. 664 64

Desquamative gingivitis is characterized by a diffuse erythema of the marginal and attached gingivae associated with areas of vesiculation, erosion, and desquamation. Desquamative gingivitis is not a disease sui generis but represents a reaction pattern of the gingivae to various stimuli. Cicatricial pemphigoid, lichen planus, and pemphigus vulgaris may present as desquamative gingivitis. We observed forty-one patients whose disease was limited to the gingiva; studied them by light and direct immunofluorescence microscopy; classified them according to clinical, histologic, and immunopathologic observations; and followed them for an average of 3 years. Two patients had pemphigus vulgaris, and one each had lichen planus and contact stomatitis. Thirty-seven were classified as cicatricial pemphigoid suspects. In eighteen patients, the gingivitis developed into cicatricial pemphigoid, and in nineteen, it remained limited to the masticatory mucosa. Disease evolution is slow. The response to anti-inflammatory therapy, including topical corticosteroids and systemic dapsone or sulfapyridine, has been gratifying.
J Am Acad Dermatol 1982 Dec
PMID:Desquamative gingivitis: clinical, histopathologic, immunopathologic, and therapeutic observations. 675 83


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