Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0038362 (stomatitis)
 8,852 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Drug-induced agranulocytosis may be type I (involving the drug, antibodies and neutrophils), type II (associated with accumulated drug toxicity in hypersensitive persons), or type III (representing different etiologies induced by immune and toxic mechanisms). The pyrazolones (amidopyrine, dipyrone and butazones), phenothiazine derivatives, antithyroid drugs, and antibiotics are thought to be causative agents in agranulocytosis. The symptoms may involve sudden onset of high fever, sore throat with ulcerative angina, or stomatitis. Diagnosis of agranulocytosis is confirmed by severe granulocytopenia (0-0.5 X 10(9)/l), but bone marrow examination is required to rule out aplastic anemia and cancer. Treatment of drug-induced agranulocytosis involves immediate withdrawal of the incriminated drug. In most patients, granulocyte, reticulocyte, and thrombocyte cell counts overshoot in the regenerative phase of drug-induced agranulocytosis.
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PMID:Hematologic effects of antipyretic analgesics. Drug-induced agranulocytosis. 635 69

Benzydamine HCL--Tantum Verde is a non-steroid drug of anti-inflammatory, pain-killing and antibacterial activity. The preparation is very easy to use in the form of mouth and throat wash, nebuliser or 3 mg lozenges. It is non-toxic and does not have side-effects. It allows the patients to improve their ability to eat foods and reduces throat discomfort and pain. On the basis of literature and own observation it is to be stated that Tantum Verde has substantial usefulness in the treatment of various, inflammatory conditions, radiotherapy induced mucositis in anti-neoplastic induced stomatitis, in angina, in neoplasms with necrosis, after surgical operation of the mouth and pharynx, after intubation and endoscopic surgery in the larynx.
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PMID:[The use of benzydamine Hcl -- Tantum Verde -- in otolaryngology]. 1149 44

Nicorandil is a vasodilator used to control angina. It has been associated with oral ulceration and stomatitis that resolves upon withdrawal of the drug. We report a series of five patients with non-specific anal ulceration, all of whom received nicorandil for symptomatic control of ischaemic heart disease. Histological appearances were similar and the ulcers healed on withdrawal of the drug. Our results suggest that nicorandil might be a cause of anal ulceration.
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PMID:Nicorandil associated anal ulceration. 1249 98

The clinical appearance of fuso-spirillar infection in patients with a serious impairment of the immunitary system was the starting-point for a historical study. At the end of nineteenth century two european researchers clarified the cause of many infections. Association of a spindle-shaped bacillus with a spirillar one was shown to cause several pathologies: necrotic ulcerous stomatitis, pseudomembranous angina, hepatic abscess, otitis, pneumonia, etc. The identification of such bacteria contributed to improving further differential diagnosis with diphteria
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PMID:[Plaut-Vincent's angina] 1274 49

Uremic stomatitis is a rare mucosal disorder associated with renal disorders. Here, we report a case of a 42-year-old male patient suffering from diabetes, angina pectoris, with white curdly pseudomembrane over the dorsal surface of the tongue, which was diffuse. The etiology, clinical features, and treatment are discussed.
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PMID:Uremic stomatitis. 2255 11