Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0038362 (
stomatitis
)
8,852
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Ammonium 5-tungsto-2-antimoniate (
HPA
23) protected micr partially or completely against two strains of encephalomyocarditis (EMC) virus and one strain of vesicular
stomatitis
(VSV) virus. The best protective effect was obtained with EMC strain VR 129 and VSV when a single i.p. injection of
HPA
23 was administered shortly before virus inoculation. Mice protected by
HPA
23 against EMC strain VR129 had virus titres in the blood and brain similar to those in untreated mice. A synergism between interferon and
HPA
23 was observed in mice infected with EMC VR129. Our results demonstrate the in vivo activity of
HPA
23 against two lethal viral infections and suggest that, at least in mice infected with EMC, death may not be related solely to virus multiplication.
...
PMID:Effect of ammonium 5-tungsto-2-antimoniate on encephalomyocarditis and vesicular stomatitis virus infections in mice. 17 29
