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Query: UMLS:C0038362 (stomatitis)
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The main purpose of the present study was to determine the qualitative and quantiative effect of various infectious epsiodes on the blood serum levels of retinol and retinol-binding protein (RBP). Twenty-four children and 30 adult subjects were studied. The infections studied included chickenpox (n = 7); bronchitis (n = 9) upper respiratory infection (n = 30); tonsillitis (n = 2); diarrhea (n = 2) and one case each of: febrile stomatitis, nonspecific gastrointestinal alteration, urinary infection and shigellosis. In addition to retinol and RBP, the study determined changes in serum carotene, proteins, albumin and globulins. The results clearly demonstrate the marked depressing effect of infections on serum retinol, with a magnitude which in many cases reached more than 20 micrograms/dl, and in others more than 30 micrograms/dl. The RBP levels were significantly correlated with retinol, decreasing proportionally with infection. Serum albumin also decreased in most instances; and the globulin levels of the children, but not of the adults, were significantly higher during the infections. Carotene did not show important variations. The effects were more intense when fever accompanied the infectious episodes. These results are considered of great public health significance, in view of the large majorities, mainly children, who ordinarily subsist with very low serum retinol levels in the underdeveloped regions of the world. As infections attack these underpriviledged children, their serum retinol and RBP levels will likely drop a magnitude similar to that observed in the subjects of this study. They may then reach even more critically deficient retinol levels and be in serious danger of developing a severe acute state of clinical vitamin A deficiency.
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PMID:[Decrease in serum levels of retinol and its binding protein (RBP) in infection]. 57 85

The effects of environmental factors in the morbidity pattern of 893 children under 5 years of age living in the urban, urban slum, and rural areas of Varanasi are investigated. 273 children belonged to an urban area, 284 to urban slum area, and 336 to a rural area. All 3 areas have general outpatient services as well as underfive clinics. Data on childrearing practices, anthropometric measurements, and morbidity are recorded in the health cards of the children. Various illnesses observed included gastroenteritis, upper respiratory tract infection, stomatitis, constipation, fever, pica, anemia, Vitamin A deficiency, measles, chicken pox, whooping cough, and others. Total illnesses per child were higher in urban slum and rural children compared to the urban group (chi-square=132.7, p0.001). Children who lived in pucca and mixed houses in urban slum and rural areas had significantly higher morbidity compared to the urban group (pucca houses, chi-square=77.01, p0.01; mixed houses, chi-square=16.98, p0.001). The incidence of morbidity was higher in children who lived in inadequately ventilated kachcha houses, had poor source of water supply through open wells and practiced open field defecation compared to those who lived in pucca houses with adequate ventilation, utilized tap water, and were using service latrines. The findings suggest the need to educate mothers and to improve sanitation in order to maintain hygienic conditions for improving the health status of the children. A safe drinking water scheme should be immediately instituted in the crowded urban slums or rural areas. The few wells in villages should be improved and water chlorinated by bleaching powder or chlorine tablets.
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PMID:Influence of environmental factors on underfive morbidity. 730 16

The objective of this study was to assess the nutritional status of adolescent boys and girls in a rural community in Bangladesh. Between December 1996 and January 1997, a cross-sectional survey was carried out in 803 households, each containing at least one adolescent, sampled consecutively from four purposely-selected villages in Rupganj Thana, Narayanganj district. Initially, the guardians of 1483 healthy and unmarried 10-17 year old adolescents (51% boys and 49% girls) were interviewed about family structure and socio-economic status. Out of these children, 906 (47% boys and 53% girls) from 597 households were weighed, had their height and MUAC measured and were clinically examined. Blood was then collected from 861 adolescents for haemoglobin estimation. The median monthly income per person in these 597 families was approximately Taka 554 (US $12). Twenty seven per cent of the household heads were labourers, 21% were solvent farmers, 14% ran small scale businesses and 6% were unemployed. Sixty seven per cent of adolescents were thin (defined as BMI < 5th centile of WHO recommended reference) with 75% boys and 59% girls being affected. The percentage of thin adolescents fell from 95% at age 10 years to 12% at age 17 years. The prevalence of stunting (height for age < 3rd centile NCHS/WHO) was 48% for both boys and girls and rose from 34% at age 10 to 65% at age 17. On clinical examination angular stomatitis was present in 46%, 27% had glossitis, 38% had pallor, 11% had dental caries, 3.2% had an conspicuously enlarged thyroid and 2.1% had eye changes of vitamin A deficiency. According to INACG (International Nutritional Anaemia Consultative Group, 1985) cut-off values, 94% of the boys and 98% of the girls were anaemic. We conclude that rural Bangladesh adolescents suffer from high rates of malnutrition and almost universal anaemia. Nutritional interventions to target this population are urgently required.
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PMID:Adolescent nutrition in a rural community in Bangladesh. 1083 32