Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038362 (stomatitis)
 8,852 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Denture stomatitis (chronic atrophic candidosis) is a very common complication to the wearing of complete dentures. The infection is due to a contamination of the denture by yeasts. In a number of studies the clinical effect of Hibitane when used as a denture disinfectant has been studied. It was found that Hibitane (0.2--2%) caused a significant amelioration of inflamed palatal tissues and a reduction in the number of yeast cells harbored on the palatal mucosa and the fitting surface of the dentures. However, relapse of the infection was frequent after treatment was sustained. It was concluded that Hibitane could not be recommended for routine denture disinfection, first, because it caused staining of the dentures, second, because of the relative resistance of the yeast to the action of the drug. However, it seems justified to use Hibitane prophylactically as a denture disinfectant in patients who are highly susceptible to developing disseminating or systemic candidosis. Hibitane is a valuable drug in the treatment of denture stomatitis when used as a denture disinfectant.
 ...
PMID:Hibitane in the treatment of oral candidiasis. 35 Sep 5

Denture stomatitis is an erythematous disorder of the denture-bearing tissues, especially the maxillary hard palate. Frequently it mimics many oral lesions. Early diagnosis of the lesion is essential to assure rational therapy. A diagnostic procedure based upon the enumeration of Candida albicans appeared to be feasible. A control group of twenty fully dentate subjects with no clinical evidence of stomatitis was sampled to establish normal concentrations of C. albicans in the oral flora. Samples were taken from a triangular area of the hard palate, serially diluted in broth, and all dilutions were incubated aerobically. In the control population, C. albicans never exceeded 100 organisms per square centimeter per subject sample. A population of edentulous patients with denture stomatitis, prior to any therapy, was similarly sampled. In many of these patients the concentration of C. albicans always exceeded 10,000 organisms per square centimeter per patient. The patients received denture replacements and antimycotic antibiotic therapy. Follow-up cultures were taken 4 to 6 weeks after completion of therapy. All patients were found to be free of denture stomatitis.
 ...
PMID:The role of C. albicans in denture stomatitis. 37 72

The prevalence and microbiology of macrophotographically documented denture stomatitis were studied in denture wearers participating in an interdisciplinary health-monitoring project (Koster Health Project) on the Koster islands, Sweden. Upper dentures were used by 26.6% of the adult population, and 59.2% of the denture wearers had stomatitis. Denture stomatitis type I was identified as sialadenitis. The more severe forms of denture stomatitis (types II and III) demonstrated increased recovery of microorganisms in the palatal mucosa in addition to sialadenitis. Only one proband showed increased growth of fungi. Hemophilus spp. and Bacteroides spp. were the predominating microorganisms in stomatitis types II and III. Shifts in the normal oral flora are suggested to be an important factor for the development of denture stomatitis. It is concluded that bacterial colonization on the palatal mucosa may play an important role in denture stomatitis in this relatively healthy population.
 ...
PMID:The predominant microflora of the palatal mucosa in an elderly island population. 163 7

Denture stomatitis is a clinical inflammatory picture that is seen at oral mucosa of the upper chin of patients who use removable dentures. There are various reasons of denture stomatitis. In order to detect the presence rate of C. albicans on lesions as the most important factor and the factors which effect this situation, 41 patients (31 with denture stomatitis and 10 as controls) were chosen. The smears obtained from the hard palate of the patients were microbiologically investigated. C. albicans was found to be the causative agent in 35.4% of the cultures which have shown growth. The relationship of sex, age and the period of denture usage was investigated in these cases.
 ...
PMID:[The role of Candida albicans in denture stomatitis]. 188 62

A previous study suggested that denture plaque played an etiologic role in denture stomatitis. In daily practice, it is important to instruct denture wearers about denture plaque control. In this study, the major areas of investigation were the degree of denture stomatitis and denture plaque, denture hygiene habits, wearing habits and age of present denture. 643 patients wearing dentures (1981-1988) were selected, from 47 to 91 years old. The following results were obtained. 1. About 50 percent of the 643 patients used brush for cleaning their dentures. The number of people wearing dentures during sleep was fewer than those who preferred removal of dentures during sleep. 2. Soaking dentures in denture cleanser reduced the degree of denture stomatitis and denture plaque. 3. The patients wearing dentures during sleep showed much more occurrence of denture stomatitis than those who had not that habit. 4. Denture stomatitis occurred frequently with increasing the age of the present denture. The present results indicate that the occurrence of denture stomatitis is closely related to the quality of the maintenance of denture.
 ...
PMID:[Clinical survey on denture stomatitis. 2. The relation between the maintenance of denture and denture stomatitis]. 213 23

Denture stomatitis is a very frequent complication of the denture wearers. In this study, the relation between denture plaque and denture stomatitis was evaluated by a simplified culture (STOMASTAT). 583 patients wearing dentures (1981-1987) were selected, from 47 to 91 years old. The following results were obtained. 1. Degree of denture plaque in 583 patients was severe, moderate, and no detection: 30, 35 and 35%, respectively. 2. Grade of denture stomatitis in 583 patients was severe, moderate, and no symptom: 24, 36 and 40%, respectively. In this survey, the occurrence of denture stomatitis was about 60%. 3. The good correlation between degree of denture plaque and grade of denture stomatitis was recognized in this study. The present results suggest that denture plaque plays an etiologic role in denture stomatitis and, in daily practice, it is important to instruct denture plaque control for denture wearers.
 ...
PMID:[Clinical survey on denture stomatitis. 1. Relation between denture plaque and denture stomatitis]. 248 96

Three hundred patients with complete dentures were examined, to find out if there exists a relationship between denture cleansing and denture stomatitis prevalence. The study revealed that: 1. Denture stomatitis prevalence was 46%. 2. Mechanical means for denture cleansing were used by 84.67% of all patients, chemical means for denture cleansing were used by 5.33% and a combination of mechanical and chemical means by 10%. 3. Dentures with satisfactory cleanliness were used by 50.33% of the whole sample of patients and dentures with unsatisfactory cleanliness by 49.67% of all patients. 4. There exists a strong significant relationship (p less than 0.001) between dentures with unsatisfactory cleanliness and denture stomatitis prevalence. 5. There exists no significant relationship (p less than 0.05) between methods for denture cleansing and denture stomatitis prevalence.
 ...
PMID:[Denture cleansing and denture stomatitis. Clinical investigation]. 264 May 28

Denture stomatitis has been reported in 11-67% of complete denture wearers. It is more common on the palatal mucosa and in female patients. In Newton's type I denture stomatitis, where the inflammation remains focal, trauma seems to be responsible. In Newton's types II and III denture stomatitis, where the denture-bearing mucosa is diffusely involved, most workers assert that the aetiology is multi-factorial. Evidence is presented incriminating Candida albicans colonization of the fitting surface of the prosthesis in many cases of denture stomatitis promoted by continuous denture wearing. Allergic and primary irritant reactions to the denture base material, systemic predisposing factors including dietary deficiency and haematological disorders, also play a part. In most cases of denture stomatitis, elimination of denture faults, control of denture plaque and discontinuous denture wearing are sufficient treatment. The routine use of antiseptic or antimycotic drugs seems unnecessary.
 ...
PMID:Denture stomatitis: a review. 329 86

Denture sore mouth is most often caused by improperly fitting dentures. Ulcers, stomatitis, hyperplasia, bone resorption, and chronic candidiasis may develop under improperly fitting dentures. If extensive bone resorption occurs, dental implants may be necessary. Malignant changes can develop.
 ...
PMID:Denture sore mouth. 331 46

The clinical and pathological study was performed in order to determine the histopathological and cytoimmunological characteristics of denture stomatitis. All specimens were biopsy materials from seventeen patients with denture stomatitis. Normal palatal mucosae from ten patients served as the control. In addition to the usual staining methods, naphtol AS-D chloroacetate esterase stain and peroxidase-antiperoxidase method were used to detect mast cells and plasma cells. Denture stomatitis could be divided into atrophic and hyperplastic types. The former showed a smooth and atrophic mucosa. The latter showed a large number of exophytic projections which were composed of marked acanthosis and submucosal fibrosis, and was further subdivided into granular and papillary subtype according to the size of projections. In the present study, there were six cases of the atrophic type, and eleven cases of the hyperplastic type (consisting of seven granular and four papillary subtypes). The hyperplastic type was more frequently observed in patients with partial dentures compared with complete dentures and was associated frequently with ill fitting of the denture base as well as agglutination of denture plaque. Cytoimmunological study revealed that there was a pronounced increase of plasma cells, especially IgG- and IgA-producing cells, and a moderate increase of lymphocytes as well as mast cells in both types of denture stomatitis. Mast cells were always noted in the area with marked plasma cell infiltration, suggesting an intimate relation between both cells. These findings suggest that the immunological reactions play some role in the pathogenesis of denture stomatitis.
 ...
PMID:Clinico-pathological study on denture stomatitis. 348 90


1 2 3 4 Next >>