Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0038362 (stomatitis)
 8,852 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper describes an objective system of monitoring the performance of disease surveillance. The system was developed through dialogue with a number of countries in Africa and adopted as part of the Global Rinderpest Eradication Programme of the Food and Agriculture Organization of the United Nations. The performance monitoring system uses a clinical stomatitis-enteritis case definition, an outbreak investigation classification scheme, and a series of eight performance indicators to measure the sensitivity, specificity and timeliness of the surveillance system. Field-testing indicates that the approach is successful when good record-keeping is practiced and highlights the importance of dialogue in helping to ensure that the system is simple and acceptable. The system provides a quantitative measure of the efficacy of national disease surveillance programmes and of the quality of data derived from such programmes for use in international disease control, animal health information exchange and trade risk analysis.
 ...
PMID:Rinderpest surveillance performance monitoring using quantifiable indicators. 1500 41

The combination of 5-flourouracil (5-FU) and leukovorin is widely used as adjuvant chemotherapy for metastatic colorectal carcinoma. The most common clinical side effects of 5-FU are related to its gastrointestinal toxicity, chiefly stomatitis and diarrhea. The latter may be severe in up to 30% and occasionally is life-threatening. We describe a case of therapy-induced enteritis presenting as acute abdominal pain and present the computed tomographic (CT) findings. In light of the prevalence of this regimen, the potential morbidity of this complication, and a paucity of CT examples in the radiologic literature, this case illustrates an important adverse effect of this medication. Early recognition and treatment should avoid significant morbidity and mortality.
 ...
PMID:Enteritis as a complication of adjuvant combination chemotherapy using 5-fluorouracil and leukovorin: clinical and helical computed tomographic features. 1523 87

This report describes the pathological and immunohistochemical findings in naturally infected lambs from three outbreaks of peste des petits ruminants in Mugla and Aydin provinces of the Ege district of Turkey. At necropsy, ulcerative stomatitis, catarrhal or fibrinous bronchopneumonia, and acute catarrhal enteritis were observed. Histopathologically, syncytial cells containing inclusion bodies were seen in the tongue and in the buccal, labial and soft palate mucosae. In pneumonic lungs, syncytial cells were present in the alveolar lumina, and cytoplasmic inclusion bodies in epithelial cells of the bronchi and bronchioli. Immunohistochemically, viral antigen was strongly labelled in the lung, oral tissues and small intestine.
 ...
PMID:Characteristic and non-characteristic pathological findings in peste des petits ruminants (PPR) of sheep in the Ege district of Turkey. 1527 53

Digestive lesions were observed in 84 of 136 sea turtles (128 Caretta caretta, four Chelonia mydas and four Dermochelys coriacea) stranded in the Canary Islands between January 1993 and December 2001. In the oral cavity ulcerative and necropurulent stomatitis were the most frequently observed lesions, and in the oesophagus ulcerative and fibrinous oesophagitis, and traumatic oesophageal perforation were most frequently observed; all these lesions were mainly associated with the ingestion of fishing hooks. Different histological types of gastritis were observed in 35 of the turtles; necropurulent and fibrinous gastritis were associated with bacterial infections caused mainly by Proteus species, Vibrio alginolyticus, and Staphylococcus species, and larval nematodes of the genus Anisakis were responsible for a form of parasitic gastritis observed in 16 of the turtles. Different histological types of enteritis, including catarrhal, fibrinous, necropurulent and necrotising enteritis, affected 36 turtles; a wide range of gram-negative and gram-positive bacteria, including Bacillus species, Escherichia coli, Pasteurella species, Proteus species, Staphylococcus species, Streptococcus species and V. alginolyticus, were isolated from these lesions. All the cases of necrotising enteritis were associated with intestinal intussusception caused by the ingestion of monofilament fishing lines. Necrotising and/or multifocal granulomatous hepatitis were the lesions most commonly observed in the liver; they affected 29 of the turtles and were associated with Aeromonas hydrophila, Citrobacter species, E. coli, Proteus species, Staphylococcus species and V. alginolyticus infections. According to the stranding reports and the gross and histological lesions observed, 33 of the turtles had digestive lesions associated with the ingestion of hooks and monofilament lines, and two had lesions associated with the ingestion of crude oil.
 ...
PMID:Digestive pathology of sea turtles stranded in the Canary Islands between 1993 and 2001. 1535 77

Peste des petits ruminants (PPR) is an acute febrile viral disease of goats and sheep characterised by mucopurulent nasal and ocular discharges, necrotising and erosive stomatitis, enteritis and pneumonia. The disease is endemic in India and causes large economic losses each year due to the high rates of mortality and morbidity in infected sheep and goats. The present study reports observations from 58 laboratory confirmed outbreaks of PPR and provides details of the prevalence of antibodies to PPR virus (PPRV) in 4,407 serum samples of small ruminants. Most of the clinical specimens used for the study originated from the northern and central parts of India. Serum samples used for the detection of antibodies to PPRV were derived from a greater number of regions within the country, however, these samples may not be a true representation of the target population (unvaccinated sheep and goats over 3 months old). Indigenously developed monoclonal antibody-based diagnostic kits were used for the detection of PPRV antigen (sandwich enzyme-linked immunosorbent assay [ELISA]) and antibody (competitive ELISA). Findings suggested that the disease outbreaks were more severe in goats than sheep and that the frequency of disease outbreaks was greater between the months of March and June (51.7%) as compared to other periods of the year. Based on the screening of the 4,407 sera samples, the antibody prevalence of PPRV in small ruminants in India was 33% (95% confidence interval: 32.3% to 33.7%). The prevalence of antibodies to PPRV was noted to differ between species (i.e. sheep versus goats), age groups and geographical regions. A greater proportion of the sheep (36.3%) versus the goat (32.4%) population was infected with PPRV. The distribution and prevalence of antibodies to PPRV among various age groups of animals indicated that goats were exposed at an earlier age than the sheep, suggesting that goats may be more susceptible to infection with PPRV. A greater number of positive cases were observed in the southern and southwestern part of the country (30%-60%) as compared to northern India (10%-30%). These findings may be correlated with variations in the sheep and goat husbandry practices within different geographic regions, the topography of different states and the socio-economic status of individual Indian farmers.
 ...
PMID:Prevalence and distribution of peste des petits ruminants virus infection in small ruminants in India. 1586 76

An outbreak of peste des petits ruminants (PPR) was recorded in Kalubia province, Egypt in 2006, affecting a large population of migratory goats and sheep over a huge geographical area. Epidemiological, clinical and laboratory investigations were performed. Diseased animals showed pyrexia, erosive stomatitis, enteritis and bronchopneumonia. Clinical manifestations were more severe in goats. The overall morbidity, cumulative mortality and case fatality rates were 26.1%, 10.5% and 40.2%, respectively, and were significantly higher in young animals. Post-mortem examination showed emaciation, congested mucous membranes, lymphadenopathy, hepatosplenomegaly, haemorrhagic necrosis of the abomasal and intestinal mucosa, pleurisy and lung consolidation. Forty oculonasal swabs and 243 serum samples from diseased animals were tested for PPR antigen and antibodies using immunocapture and competitive enzyme-linked immunosorbent assays (ELISA), respectively. PPR antigen was detected in 30/40 (75%) of the swabs. PPR virus was identified in inoculated Vero cells using immunocapture ELISA and fluorescent antibody technique (FAT); 33/40 (82.5%) and 36/40 (90%) samples were positive, respectively. Of 243 sera, 154 (63.4%) contained PPR antibodies. Circulation of PPR among the migratory sheep and goat flocks was demonstrated. Strict serosurveillance and monitoring of PPR with vaccination of migratory flocks at borders is required for effective control of the disease.
 ...
PMID:An outbreak of peste des petits ruminants in migratory flocks of sheep and goats in Egypt in 2006. 2130 63

The experiment describes for the first time the clinicopathological features of the co-infection of Peste des petit Ruminants (PPR) virus and Mannheimia haemolytica,in goats. Twenty clinically healthy goats, six months of age were used. 15 goats were infected by intratracheal inoculation of 1ml of pure cultured 106.5 TCID50 PPR virus grown in Baby hamster kidney cell lines, and a week later,1 ml of pure culture (109 CFU) of Mannheimia haemolytica (MH)A2 to study its clinico-pathological features and five goats served as controls. The clinical signs were observed and two goats were euthanized at predetermined intervals for gross examinations, bacteriological, virological and histopathological investigations on tissues collected using standard techniques. The clinical signs were severe and the order of manifestation was anorexia, pyrexia, dyspnea, oculo-nasal discharge, recumbency and death. The lesions observed were severe fibrinous bronchointerstitial pneumonia and pleurisy with thickened alveolar septa, edema and neutrophilic infiltrations of the interstitium with giant cells. There was also marked erosive stomatitis and acute enteritis. The average percentage lung consolidation for the infection was 7.01% and the right lung was more affected (p<0.05) while the overall mortality was 33.3%. MHA:2 and PPR virus were re-isolated from the lungs. The clinicopathological features observed showed that goats were susceptible to co- infection of PPR and Mannheimiosis which was severe and fatal. The data should help veterinarians and other medical experts to recognize cases of bacterial complicated viral infection and be informed of the approach to the treatment of such conditions.
 ...
PMID:Clinicopathological observations in experimental peste des petit ruminants virus and Mannheimia haemolytica A:2 co-infection in goats. 2365 26

Peste des petits ruminants (PPR) is an acute, highly contagious fatal disease of small ruminants characterized by high fever, ocular and nasal discharge, pneumonia, erosive stomatitis and severe enteritis that ultimately results in high mortalities. Peste des petits ruminants virus (PPRV) is widely distributed and endemic in several African, middle eastern and south Asian countries and it poses a threat to European countries. Egyptian veterinary medical authorities stated that Egypt is free from PPRV and the only measures for disease control are test and slaughter of infected population to maintain the free status. The aim of our investigation was to detect PPRV in Ismailia province as an indicator of the infection status in Egypt and perform molecular characterization of the emerging virus to gain insight into the origin of circulating virus. A total of 40 representative clinical samples, from a single goat case and goat flock in 2010 and sheep flock in 2012, were tested for PPRV by RT-PCR. About 21 (52.5%) samples were positive. The phylogenetic analysis of the detected viruses revealed circulation of PPRV lineage IV. The circulating viruses are closely related to Sudanese and Saudia Arabian strains with nucleotide identity ranged from 99.2% to 99.6%, respectively. Also, it is closely related to Moroccan 2008 viruses with identities ranged from 97.6% to 98%. Epidemiological investigation at the national level is recommended for monitoring PPRV spread and implementing an appropriate control program.
...
PMID:Emergence of peste des petits ruminants virus lineage IV in Ismailia Province, Egypt. 2520 Jul 22

The Eastern Ghats of India is well known for its wealth of natural vegetation and Shervaroy is a major hill range of the Eastern Ghats of Tamil Nadu. Ethnomedicinal studies in the Eastern Ghats of Tamil Nadu or the Shervaroy Hills have been carried out by various researchers. However, there is not much information available on ethnoveterinary medicine in the Eastern Ghats of India. The aim of this study was to examine the potential use of folk plants as alternative medicine for cattle to cure various diseases in the Shervaroy Hills of the Eastern Ghats. Based on interactions with traditional medicine practitioners, it has been observed that a total of 21 medicinal plants belonging to 16 families are used to cure various diseases such as mastitis, enteritis, arthritis, stomatitis, salivation from the mouth, wounding, and conjunctivitis in animals. It has been observed that the traditional knowledge of ethnoveterinary medicine is now confined only among the surviving older people and a few practitioners in the tribal communities of the Shervaroy Hills. Unfortunately, no serious attempts have been made to document and preserve this immense treasure of traditional knowledge.
...
PMID:Ethnoveterinary medicine of the Shervaroy Hills of Eastern Ghats, India as alternative medicine for animals. 2687 Jun 89

We present a case of a patient with drug-induced hypersensitivity syndrome (DIHS) caused by salazosulfapyridine combined with syndrome of inappropriate secretion of antidiuretic hormone (SIADH) caused by interstitial pneumonia (IP). A 67-year-old man with a past history of rheumatism (RA) presented with right hemiparalysis and aphasia as the chief complaints. A diagnosis of left embolic cerebral infarction following trial therapy for RA based on computed tomography findings was made, and external decompression was performed. Salazosulfapyridine was newly started on day 7. Dabigatran was started on day 37. On day 41, the patient developed fever. On day 42, edema and erythema appeared on his face, and erythema and rash appeared on his trunk and extremities, with gradual transition to erythroderma. The drug eruption was initially attributed to the dabigatran. Various symptoms of organ dysfunction (enteritis, myocarditis, interstitial pneumonia, hepatic disorder, stomatitis, and others) then appeared and persisted; hence, a diagnosis of DIHS associated with human herpes virus 6 and cytomegalovirus infection induced by salazosulfapyridine was suggested, and the oral administration of salazosulfapyridine was discontinued on day 53. Hyponatremia was observed in association with exacerbation of IP. Due to low serum osmotic pressure and prompt improvement of the serum sodium level by fluid restriction, the SIADH was attributed to IP. In this case, steroid pulse therapy followed by gradual decrease therapy prevented worsening of the condition.
 ...
PMID:A case of drug-induced hypersensitivity syndrome induced by salazosulfapyridine combined with SIADH caused by interstitial pneumonia. 3153 76


<< Previous 1 2 3 Next >>